Abstract: Provided herein are DLL3 binding agents and chimeric antigen receptors (CARs) comprising a DLL3 binding molecule that specifically binds to DLL3; and immune cells comprising these DLL3-specific CARs, e.g., CAR-T cells. Also provided are methods of making and using DLL3-specific CARs, and immune cells comprising DLL3-specific CARs.

Abstract: The present disclosure generally relates to a monocoque body for an unmanned underwater vehicle (“UUV”) comprising a nose portion, a tail portion, a body interior surface, a body exterior surface. The monocoque body can be a one-piece structural shell made of fiber reinforced polymer. The UUV may further include transverse structural members.

Abstract: A computer system and method generates one or more commenting features on a canvas, wherein each commenting feature carries at least one comment from a given source. Each commenting feature can include a pin component and a comment body element. The pin component is associated with a corresponding location on the canvas. The computer system and method enable the user to move the comment body element about at least a region of the canvas to view the at least one comment from the given source, while rendering the pin component to coincide with the corresponding associated location of the canvas.

Abstract: A plasma confinement system includes an enclosure, one or more internal magnetic coils suspended within the enclosure in a plasma region, and one or more supports configured to support the one or more internal magnetic coils suspended within the enclosure. Each support of the one or more supports includes a first end and a second end opposite the first end. The first end is coupled to an interior portion of the enclosure and the second end is coupled to a component disposed within the plasma region. Each support further includes electrical conducting material disposed between the first end and the second end. The electrical conducting material is configured to, when supplied with one or more electrical currents, generate a magnetic field having a magnetic field gradient that varies along the support from the first end to the second end.

Abstract: Systems and methods are provided for pumps that deliver optimized torque characteristics and volumetric efficiency. A system includes a housing defining a surface and a rotor defining a face. A face clearance is defined between the face and the surface. The face clearance is variable in magnitude and determinative of target performance characteristics of the pump system. The housing is made of a material selected to have a thermal expansion characteristic and the rotor is made of a second material selected to have another thermal expansion characteristic. The thermal expansion characteristics deliver the target performance characteristics of the pump system.

Abstract: The present disclosure generally relates to digital identification credential user interfaces.

Abstract: A polymer composition that includes a blended resin having a viscosity below 10 pascal-seconds before exposure to actinic radiation is provided. The blended resin includes a first base component that is photocurable, and the first base component includes (i) a first siloxane polymer including a plurality of thiol groups and (ii) a second siloxane polymer including a plurality of functional groups with unsaturated carbon-carbon bond. The blended resin also includes a photoinitiator, a second base component that is condensation curable, and a catalyst. The first base component is configured to polymerize into a primary polymer network and the second base component is configured to polymerize into a secondary polymer network. Furthermore, the primary and secondary polymer networks together form an interpenetrating polymer network.

Abstract: The disclosure relates to a hearing aid for placement in an ear canal, the hearing aid having a proximal end and a distal end, the proximal end is inserted into the ear canal to face the tympanic membrane, the distal end is opposite. The hearing aid comprises a shell customized for the ear canal. The shell comprises an inner space configured for at least partly receiving a rechargeable battery, a charging arrangement, at least one microphone arrangement, and an integrated circuit. The hearing aid comprises a faceplate comprising an upper face and a lower face, the upper face being exposed at the distal end when the shell is placed in the user's ear canal. The faceplate is configured for closing the inner space, wherein the IC is arranged between the faceplate and the proximal end.

Abstract: The present invention provides a compound of Formula (I) wherein R is (II) or (III), or a pharmaceutically acceptable salt thereof, useful for treating psoriasis, systemic lupus erythematosus, or type 1 diabetes.

Abstract: A system, method, and apparatus is provided for integrating multiple payment options on a merchant webpage. The method includes receiving, from a merchant system associated with a merchant webpage, a payment data capture request, generating, with at least one processor, web payment capture data based on the payment data capture request, the web payment capture data configured to adapt the merchant webpage to receive payment information input by a user, communicating, to the merchant system, the web payment capture data, receiving, directly from a client computer via at least one client-side script executed by the client computer based on the web payment capture data, the payment information input by the user, generating, with at least one processor, a transient payment token based on the payment information, and directly communicating the transient payment token to the client computer.

Abstract: A system for detecting whether a file including content is associated with a cyber-attack is described. The content may include an executable file for example. The system includes an intelligence-driven analysis subsystem and a computation analysis subsystem. The intelligence-driven analysis subsystem is configured to (i) receive the file, (ii) inspect and compute features of the file for indicators associated with a cyber-attack, and (iii) produce a first output representing the detected indicators. The computational analysis subsystem includes an artificial neural network to (i) receive a network input being a first representation of at least one section of binary code from the file as input, and (ii) process the first representation of the section to produce a second output. The first output and the second output are used in determination a classification assigned to the file.

Abstract: The present invention provides a compound of Formula I: wherein R is or a pharmaceutically acceptable salt thereof, useful for treating psoriasis, systemic lupus erythematosus, or type 1 diabetes.

Abstract: A hearing aid for placement in an ear canal of a user, includes: a shell; a faceplate comprising an upper face, and a lower face, and a circumference, the upper face being exposed when the shell is placed in an ear of the user; a coil arranged at the faceplate; and a button arrangement comprising a plunger configured to control an integrated circuit arranged below the coil, the coil comprising one or more windings, the one or more windings being circumferential of an inner cavity of the coil with respect to a center or longitudinal axis of the coil, the button arrangement being configured such that the plunger in at least one position extends through the inner cavity of the coil for engaging the integrated circuit.

Abstract: Embodiments of the present disclosure relate to a photomask. The photomask may include: a substrate; and one or more pixel units formed over the substrate. Each pixel unit may include: at least one polymer crystal element configured to interact with extreme ultraviolet (EUV) light based on an orientation of the polymer crystal element; and a plurality of electrodes configured to control the orientation of the polymer crystal element by applying voltage across the polymer crystal element. Each pixel unit is controlled by the respective plurality of electrodes independently, and the one or more pixel units generate a pattern for lithography upon exposure to the EUV light.

Abstract: The disclosure provides methods of generating a modulus gradient in a polymeric material, resin mixtures for such methods, and polymeric materials thereof having at least a modulus gradient.

Abstract: At least one of a method, apparatus, and system, as discussed herein and depicted in the figures that includes a first dock section, the first dock section including a first proximal end and a first distal end; a second dock section, the second dock section including a second proximal end and a second distal end; and a moveable guide system that connects the first dock section and the second dock section in a deployed position, such that the first proximal end of the first dock section abuts the second distal end of the second dock section, wherein the moveable guide system is configured to allow for the first dock section to be guided into a stowed position, on top of the second dock section.

Abstract: The present invention relates a modular cabinet system for attaching to truck or truck trailer combinations involved in the loading and unloading of comestible liquid products transferred in bulk from one or more production site(s) to one or more processing center(s) or end users. The cabinet system is installed onto the rear of the transport vehicle and over the outlet valve of the transport vehicle such that the valve of the transport vehicle is enclosed within the cabinet system. The cabinet system transforms the transport vehicle such that the transport vehicle can load and unload comestible liquid products from any site regardless of the facilities and equipment provided at the site without the need to modify and reconfigure pumping and or other aspects of the cabinet system based on the site. The cabinet system includes at least a pump compartment with a dock mating surface that is enclosed by a moveable door and a separate motor compartment also enclosed by a moveable door.

Abstract: A method for forming a transparent ceramic, in accordance with one embodiment, includes forming a green body by material jetting an ink, and processing the green body to form the ceramic to transparency. A product, in accordance with one embodiment, includes an ink for forming a transparent ceramic. The ink is physically characterized as having a density, surface tension, and viscosity configured to enable material jetting of the ink in contained, sequential droplets having a volume in the range of about 1 picoliter to about 1 nanoliter when jetted from a nozzle having an inner diameter in the range of about 10 microns to about 300 microns. A product, in accordance with another embodiment, includes a transparent ceramic, at least a portion of the transparent ceramic having layers of less than 50 microns per layer with physical characteristics of formation by material jetting.

Abstract: In one embodiment, a method includes accessing a digital image captured by a camera that is connected to a machine-detectable object, detecting a reflection of the machine-detectable object in the digital image, computing, in response to the detection, a plane that is coincident with a reflective surface associated with the reflection, determining a boundary of the reflective surface in the plane based on at least one of a plurality of cues, and storing information associated with the reflective surface, where the information includes a pose of the reflective surface and the boundary of the reflective surface in a 3D model of a physical environment, and where the information associated with the reflective surface and the 3D model are configured to be used to render a reconstruction of the physical environment.

Abstract: An exercise weight support device includes: a spool connected to a belt to suspend the device, the spool being rotatable to enable more or less of the belt to be wound therearound to change the vertical position of the device; a ratchet wheel drivingly coupled to the spool to control rotation thereof; an outer frame having a cradle and/or pair of hooks to support a bar of a free weight; a ratchet pawl connected to the outer frame at a fixed location relative thereto; and a trigger handle coupled to the spool to move the spool relative to the ratchet pawl between a non-operating position of the trigger handle causing the ratchet pawl and teeth of the ratchet wheel to engage, and an operating position of the trigger handle causing the ratchet pawl and teeth to disengage to control rotation of the spool.