Abstract: The present disclosure describes a uterine contraction device which may be utilized to treat and/or prevent postpartum hemorrhaging. The uterine contraction device includes a catheter and a pressure seal adjustably coupled to the catheter. A distal section of the catheter is configured for insertion into the uterus, and a proximal end of the catheter is configured for attachment to a vacuum device. Negative pressure generated by the vacuum device is transmitted to the distal section, while the pressure seal forms a seal at the vaginal introitus to maintain the negative pressure within the uterus to assist in contracting the uterus.