Patents by Inventor Thomas K. Hayes

Thomas K. Hayes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense formulation
    Patent number: 8383336
    Abstract: A room temperature stable and minimal aggregate liquid formulation comprises an oligonucleotide comprising Seq ID No. 1: or comprising a variant oligonucleotide in which no more than 3 non-sequential bases are different from Seq. ID NO. 1 and an aqueous carrier comprising a aggregation-preventing compound selected from the group consisting of mono and disaccharides and/or sugar alcohols.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: February 26, 2013
    Assignee: Oncogenex Technologies Inc.
    Inventors: Thomas K. Hayes, Nicole D. Krilla, Lori Nixon
  • Antisense Formulation
    Publication number: 20110098343
    Abstract: A room temperature stable and minimal aggregate liquid formulation comprises an oligonucleotide comprising Seq ID No. 1: or comprising a variant oligonucleotide in which no more than 3 non-sequential bases are different from Seq. ID NO. 1 and an aqueous carrier comprising a aggregation-preventing compound selected from the group consisting of mono and disaccharides and/or sugar alcohols.
    Type: Application
    Filed: July 13, 2009
    Publication date: April 28, 2011
    Applicant: ONCOGENEX TECHNOLOGIES INC.
    Inventors: Thomas K. Hayes, Nicole D. Krilla, Lori Nixon
  • 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries
    Patent number: 6388081
    Abstract: The present invention relates to novel 4-substituted quinoline compounds of the following formula, libraries containing such compounds, and to the generation of such combinatorial libraries composed of such compounds: wherein R1, R2, R3, R4, R5, R6, R7, R9, and Y, have the meanings provided.
    Type: Grant
    Filed: August 16, 1999
    Date of Patent: May 14, 2002
    Assignee: Lion bioscience AG
    Inventors: Thomas K. Hayes, Behrouz Forood, John S. Kiely
  • 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries
    Patent number: 6262269
    Abstract: The present invention relates to novel 4-substituted quinoline compounds of the following formula, libraries containing such compounds, and to the generation of such combinatorial libraries composed of such compounds: wherein R1, R2, R3, R4, R5, R6, R7, R9, and Y, have the meanings provided.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: July 17, 2001
    Assignee: Trega Biosciences, Inc.
    Inventors: Thomas K. Hayes, Behrouz Forood, John S. Kiely
  • Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries
    Patent number: 5925527
    Abstract: The present invention relates to novel tricyclic tetrahydroquinoline compounds of the following formula, libraries containing such compounds, and to the generation of such combinatorial libraries composed of such compounds: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, n, and Y have the meanings provided.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: July 20, 1999
    Assignee: Trega Biosciences, Inc.
    Inventors: Thomas K. Hayes, John S. Kiely