Patents by Inventor Thomas K. Hughes, Jr.

Thomas K. Hughes, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of colostrinin, constituent peptides thereof, and analogs thereof as modulators of intracellular signaling molecules
    Patent number: 7119064
    Abstract: The present invention provides methods that utilize compositions containing colostrinin, a constituent peptide thereof, an active analog thereof, and combinations thereof, as modulators of intracellular signaling molecules, for example.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: October 10, 2006
    Assignee: Board of Regents, The University of Texas System
    Inventors: Istvan Boldogh, G. John Stanton, Jerzy A. Georgiades, Thomas K. Hughes, Jr., Marian Kruzel
  • Use of colostrinin, constituent peptides thereof, and analogs thereof, as oxidative stress regulators
    Patent number: 6939847
    Abstract: The present invention provides methods that utilize compositions containing colostrinin, an constituent peptide thereof, an active analog thereof, and combinations thereof, as an oxidative stress regulator.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: September 6, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: G. John Stanton, Thomas K. Hughes, Jr., Istvan Boldogh
  • Use of colostrinin, constituent peptides thereof, and analogs thereof for inducing cytokines
    Patent number: 6903068
    Abstract: The present invention discloses a use of colostrinin, a constituent peptide thereof, and/or an analog thereof as an immunological regulator and as a blood cell regulator in animals including humans.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: June 7, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: G. John Stanton, Thomas K. Hughes, Jr., Istvan Boldogh, Jerzy A. Georgiades
  • Use of colostrinin, constituent peptides thereof, and analogs thereof to promote neuronal cell differentiation
    Patent number: 6852685
    Abstract: The present invention discloses a use of colostrinin, a constituent peptide thereof, and/or an analog thereof as a neural cell regulator in animals including humans.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: February 8, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Istvan Boldogh, G. John Stanton, Thomas K. Hughes, Jr.
  • Use of colostrinin, constituent peptides thereof, and analogs thereof, as oxidative stress regulators
    Patent number: 6500798
    Abstract: The present invention provides methods that utilize compositions containing colostrinin, an constituent peptide thereof, an active analog thereof, and combinations thereof, as an oxidative stress regulator.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: December 31, 2002
    Assignee: Board of Regents, The University of Texas System
    Inventors: G. John Stanton, Thomas K. Hughes, Jr., Istvan Boldogh
  • Compositions for conferring immunogenicity to a substance and uses thereof
    Patent number: 5807552
    Abstract: A multimer of monomers non-covalently held together by interactive peptide linkers is provided for the enhancement of the immunogenicity of a substance. These multimers are useful for stimulating or suppressing the immune system, detecting the presence of antibodies, bypassing MHC restriction in an animal, the effective presentation of antigen, suppressing autoimmune disease, inducing cytokine production, adsorption, treating a defective immune system and for use as an adjuvant.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: September 15, 1998
    Assignee: Board of Regents, The University of Texas System
    Inventors: G. John Stanton, Thomas K. Hughes, Jr., Eric M. Smith
  • Potentiation of tumor necrosis factor (TNF) of interferon B1 (IFN-B1) antiviral activities by an anti-cachexia agent
    Patent number: 5264208
    Abstract: The present invention discloses the use of a anti-cachexia agent with an antiviral agent, preferably used as a therapeutic agent in the treatment of viral infections. The anti-cachexia agent acts to potentiate the antiviral activity of the antiviral agent as much as several hundred fold. The anti-cachexia agent also acts to decrease, or halt the anti-proliferative or host destroying activities of the antiviral agent. The most preferred anti-cachexia agent of the present invention is hydrazine sulfate. The most preferred antiviral agent of the present invention is interferon, tumor necrosis factor or any combination thereof.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: November 23, 1993
    Assignee: Board of Regents, The University of Texas System
    Inventors: Thomas K. Hughes, Jr., Charlotte S. Larned