Abstract: A method for operating a machine plant having a shaft train, including: a) determining the harmonic frequency of a torsional vibration mode of the shaft train and determining mechanical stresses arising during a vibration period of the torsional vibration mode; b) determining a correlation for each torsional vibration mode between a first stress amplitude, at a position of the shaft train that carries risk of stress damage, and a second stress amplitude, at a measurement location of the shaft train, using stresses determined for the respective torsional vibration mode; c) establishing a maximum first stress amplitude for the position; d) establishing a maximum second stress amplitude, corresponding to the maximum first stress amplitude, for the measurement location; e) measuring the stress of the shaft train while rotating; f) determining a stress amplitude at each harmonic frequency; g) emitting a signal when the stress amplitude reaches the maximum second stress amplitude.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: The invention relates to a compressor arrangement for compressing a gas. The compressor arrangement comprises a drive unit with a driveshaft that can be driven in rotation and at least one compressor which comprises a compressor casing, at least one gas inlet opening formed in the compressor casing and at least one gas outlet opening formed in the compressor casing and fluidically connected to the at least one gas inlet opening. The compressor also has at least one impeller, which is arranged in the compressor casing, is connected in fixed rotation with the driveshaft and can be driven in rotation, for delivering the gas from the at least one gas inlet opening to the at least one gas outlet opening, and has at least one bearing device for bearing the at least one impeller, wherein the at least one bearing device is arranged on the compressor casing and on the at least one impeller.

Abstract: A method for operating a machine plant having a shaft train, including: a) determining the harmonic frequency of a torsional vibration mode of the shaft train and determining mechanical stresses arising during a vibration period of the torsional vibration mode; b) determining a correlation for each torsional vibration mode between a first stress amplitude, at a position of the shaft train that carries risk of stress damage, and a second stress amplitude, at a measurement location of the shaft train, using stresses determined for the respective torsional vibration mode; c) establishing a maximum first stress amplitude for the position; d) establishing a maximum second stress amplitude, corresponding to the maximum first stress amplitude, for the measurement location; e) measuring the stress of the shaft train while rotating; f) determining a stress amplitude at each harmonic frequency; g) emitting a signal when the stress amplitude reaches the maximum second stress amplitude.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: Methods and compositions are provided for detection and diagnosis of a lymphoid malignancy using high throughput sequencing of rearranged T cell receptor DNA sequences.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: In order to provide a thermostable and highly effective barrier coating on a substrate, and to protect the substrate against the effect of harmful gas components even at high temperatures, the invention provides a coated substrate comprising a barrier coating having a multiplicity of consecutive individual layers respectively of a kind differing from or similar to a neighboring individual layer, the individual layers exhibiting a layer thickness of respectively at most 50 nanometers.

Abstract: The present invention comprises a humanized monoclonal antibody that binds to the chemokine receptor CCR4. This antibody is derived from Mab 1567 and recognizes the same epitope. Binding of the invented antibody to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.

Abstract: The invention relates to a discharge vessel of a quartz glass for discharge lamps with a diffusion barrier inner layer of silicon oxide, which as a single layer is applied and/or is generated on the inner surface as well as to a method for generating and/or applying such a diffusion barrier inner layer and to the use of such a discharge vessel.

Abstract: A reactor for simultaneous coating of eyeglasses on both sides thereof. Two partial devices are provided, each with a microwave energy waveguide, a gas supply and an apparatus for evacuating the coating chamber where the first and second devices can be moved relative to each other to open and close the coating chamber. The coating chamber itself is removable from the device and includes two gas supply connections and two connections for evacuating the coating chamber as well as microwave windows for coupling in microwave energy.

Abstract: An apparatus for coating objects having a single microwave source, two or more coating chambers, and an impedance structure or a waveguide structure. The coating chambers are connected to the single microwave source. The impedance structure or waveguide structure divides the microwave energy in order to generate plasmas in the coating chambers.

Abstract: A method for producing optical functional coatings comprising niobium, tantalum, titanium or aluminum by supplying a precursor gas of low vapor pressure in a CVD coating system. A precursor selected from the group consisting of Nb, Ta, Ti, and Al compounds having a vapor pressure is maintained within a first supply container at a first temperature T1 and a first pressure p1. Precursor vapor of the precursor is supplied from the first supply container to an intermediate storage device through a first gas line which fluidly communicates the first supply container and the intermediate storage device. A carrier gas or reaction gas is supplied to the first gas line such that a mixture of the precursor with the carrier gas or the reaction gas is provided.

Abstract: The present invention is directed to an in vitro method for producing T lymphocytes. The method involves culturing bone marrow cells on a matrix seeded with keratinocytes and fibroblasts.

Abstract: The invention relates to a coated object in which coatings remain of a constant and unchanged high quality despite operating temperatures of more than 350° C. This is achieved with interlayers which deliberately interrupt and thereby stabilize the morphology of the coating.

Abstract: A scratchproof, temperature-stable protective layer, in particular a scratch-resistant protective layer for cooking hobs is provided. In addition, processes and an apparatus for producing these protective layers are provided. The protective layer includes at least one hard-material layer having a functional layer interrupted by very thin interlayers so that the functional layer has a morphologically dense columnar structure that grows substantially perpendicular to the body surface. The production of layers of this type is achieved by a magnetron sputtering process and a corresponding arrangement, with the tendency of the columnar structures to widen out being reduced by targeted interruption of the growth of the functional layers.

Abstract: The present invention is directed to an in vitro method for producing T lymphocytes. The method involves culturing bone marrow cells on a matrix seeded with keratinocytes and fibroblasts.

Abstract: The invention relates to a process for producing an object which has optical layers. According to the invention such a process comprises the following process steps: To a substrate of plastic material several optical layers are applied; the optical layers are applied by means of a chemical plasma-impulse vaporization (PICVC).