Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: The present invention relates to a method for identifying a pharmaceutically active compound that modulates the rpL35 (rpL35/rpL29)-dependent translation of at least one mRNA in a mammalian cell. The mRNA may comprise a premature termination codon (PTC), undergoes premature translation termination, causes programmed ?1 ribosomal frame shifting (?1PRF), or is a polycistronic mRNA. Furthermore a respective screening system, methods of treating or preventing a disease or condition, and compounds that modulate the rpL35 (rpL35/rpL29)-dependent translation, in particular atazanavir or derivatives thereof and artemisinin or artesunate or derivatives thereof are provided.

Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: Described herein are systems and methods for assessing a biological sample. The methods include: characterizing a speckled pattern to be applied by a diffuser; positioning a biological sample relative to at least one coherent light source such that at least one coherent light source illuminates the biological sample; diffusing light produced by the at least one coherent light source; capturing a plurality of illuminated images with the embedded speckle pattern of the biological sample based on the diffused light; iteratively reconstructing the plurality of speckled illuminated images of the biological sample to recover an image stack of reconstructed images; stitching together each image in the image stack to create a whole slide image, wherein each image of the image stack at least partially overlaps with a neighboring image; and identifying one or more features of the biological sample. The methods may be performed by a near-field Fourier Ptychographic system.

Abstract: The present disclosure relates to a gear cutting machine having a machine control as well as having at least one display for displaying machine-relevant parameters, wherein the display is multitouch-operable and allows an operator input for controlling the gear cutting machine by multifinger gestures over the display.

Abstract: The present disclosure relates to a method of setting up a gear cutting machine, wherein the gear cutting machine is equipped with at least one machine part which can be set up and the parameters relating to the set-up machine part are input into the machine control for the subsequent gear cutting process, wherein a graphical model of the machine part is virtually composed on a display element of the gear cutting machine in a user-controlled manner from one or more graphical part components and the required parameters for the following gear cutting process are derived from the graphical modeling.

Abstract: The present disclosure relates to a method of setting up a gear cutting machine, wherein the gear cutting machine is equipped with at least one machine part which can be set up and the parameters relating to the set-up machine part are input into the machine control for the subsequent gear cutting process, wherein a graphical model of the machine part is virtually composed on a display element of the gear cutting machine in a user-controlled manner from one or more graphical part components and the required parameters for the following gear cutting process are derived from the graphical modeling.

Abstract: The present disclosure relates to a gear cutting machine having a machine control as well as having at least one display for displaying machine-relevant parameters, wherein the display is multitouch-operable and allows an operator input for controlling the gear cutting machine by multifinger gestures over the display.

Abstract: A component having a laser track as a fracture initiation line, said laser track being composed of laser holes formed by a laser beam for preparing for a later separation of the component into individual components. In order to ensure that, upon separation, the fracture always extends along the laser track, fractures deviating from the laser track are avoided, and the fracture edges after fracture are formed evenly and do not have jagged edges, it is proposed that the distance between two adjacent laser holes be less than or equal to the diameter of said laser holes, in each case measured on the surface of the component.

Abstract: An engine compartment cooling system includes an axial fan assembly and a remote mount fluid cooler assembly. The axial fan assembly and the remote mount fluid cooler assemblies are mounted in clear holes in at least one of the quarter panels. The axial fan assembly exhausts engine heat outwardly from the engine compartment through the quarter panel. The fluid cooler assembly receives ambient air through the quarter panel into the engine compartment. The axial fan and fluid cooler assembles are controlled using, sensors, signal data, and a controller. The controller is programmed with the operation data so that the cooling system optimizes engine cooling while varying operation of the engine's cooling system, and the axial fan and the remote mount fluid cooler assemblies according to the invention.

Abstract: A stand-alone, portable video alarm system for monitoring a protected area selected by a user is described that includes a video detection sensor for issuing alarm system signals, including an intrusion alarm signal when the video detection sensor detects motion indicative of an intruder within the protected area, a secondary detection sensor to detect the intruder within said protected area, a modem for communicating command signals to and alarm system signals from the video alarm system, a user-controlled mobile display for transmitting said command signals to the video alarm system through said modem and for receiving said alarm status signals from the video alarm system through said modem, wherein the intrusion alarm signal is communicated from the video alarm system through the modem and onto the user-controlled mobile display only when the intruder is detected by both the video detection sensor and the secondary detection sensor.

Abstract: A component having a laser track as a fracture initiation line, said laser track being composed of laser holes formed by a laser beam for preparing for a later separation of the component into individual components. In order to ensure that, upon separation, the fracture always extends along the laser track, fractures deviating from the laser track are avoided, and the fracture edges after fracture are formed evenly and do not have jagged edges, it is proposed that the distance between two adjacent laser holes be less than or equal to the diameter of said laser holes, in each case measured on the surface of the component.

Abstract: In combination with an engine compartment having an engine, a hood, and at least two front quarter panel side walls defining an interior engine compartment, an engine compartment cooling system, is provided which includes a clear hole in at least one of the side walls positioned between a passenger compartment and a forward portion of a fender wheel well. At least one axial fan assembly has a fan housing, a plurality of fan blades, a motor shaft, and a fan motor. The fan assembly is mounted in the clear hole. A fan motor control system is operatively connected to a first temperature sensor for sensing a temperature of the engine compartment, and sending a first signal data to a controller operable to optimize a fan speed of the fan assembly based on the temperature of the engine compartment. A heated air flow path originates from the engine compartment and is exhausted outwardly through the fan assembly into an ambient air flow for cooling of the engine compartment.

Abstract: In combination with an engine compartment including an engine, a hood, and at least two front quarter panel side walls defining an interior engine compartment, an engine compartment cooling system includes a clear hole made in at least one of the side walls positioned between a passenger compartment and a forward portion of a fender wheel well. At least one axial fan assembly has a fan housing, a plurality of fan blades, a motor shaft, and a fan motor. The fan assembly is mounted in the clear hole. A fan motor controller is connected to the fan motor, and a heated air flow path, which originates from the engine, is exhausted outwardly through the fan assembly into an ambient air flow for cooling of the engine compartment.

Abstract: An alarm interface module is described that permits an alarm monitoring system to be operational through an existing wide area network (WAN) modem that is linked to an existing local area network (LAN) system wherein the alarm interface module has a first LAN port coupled to the LAN system, a second LAN port coupled to an output port of an alarm control panel of the alarm monitoring system, a WAN port coupled to the WAN modem, and a programming element capable of recognizing an identifying address dynamically assigned to the alarm control panels to route data from a remote alarm server to the alarm control panel while also permitting data communications to the LAN system from the WAN modem that are not initiated from the remote alarm server. The security system interface module of the present invention can be used with any security alarm panels, sensors, video devices, etc.

Abstract: An alarm interface module is described that permits an alarm monitoring system to be operational through an existing wide area network (WAN) modem that is linked to an existing local area network (LAN) system wherein the alarm interface module has a first LAN port coupled to the LAN system, a second LAN port coupled to an output port of an alarm control panel of the alarm monitoring system, a WAN port coupled to the WAN modem, and programming means capable of recognizing an identifying address dynamically assigned to the alarm control panels to route data from a remote alarm server to the alarm control panel while also permitting data communications to said LAN system from said WAN modem that are not initiated from the remote alarm server. The security system interface module of the present invention can be used with any security alarm panels, sensors, video devices, etc.