Patents by Inventor Thomas Kelly

Thomas Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12001480
    Abstract: A system and method for determining the extent of beneficial ownership of a target business by populating a database structure wherein businesses and ownership relationships between the business are represented by nodes and links. Steps include querying the database to establish the related ownership links; analyzing results of the query to determine ownership loops; de-looping the ownership relationships; and calculating the percentage ownership of each of the beneficial owners of the target business based on de-looped ownership relationships. A computer readable non-transitory storage medium stores instructions of a computer program, which when executed by a computer system results in performance of steps of the method. A system architecture having features uniquely suited to the task is also disclosed.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: June 4, 2024
    Assignee: THE DUN AND BRADSTREET CORPORATION
    Inventors: Stuart Swindell, Yunhong Liu, Thomas Kelly, Paul Westcott
  • Publication number: 20240140953
    Abstract: Disclosed herein are heterocyclic compounds that inhibit the binding of menin and MLL or MLL fusion proteins. Also described are specific inhibitors of menin-MLL interaction. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the menin-MLL inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, leukemia and other diseases or conditions dependent on menin-MLL interaction.
    Type: Application
    Filed: November 6, 2023
    Publication date: May 2, 2024
    Inventors: Thomas BUTLER, Jim PALMER, Ravi UPASANI, Matthew WELSCH, Sridhar VEMPATI, Brendan KELLY, Edward PAINTER
  • Patent number: 11946532
    Abstract: A vehicle drive unit that provides improved power transfer to a differential input member of a differential assembly. The vehicle drive unit is configured with an interlock system that is configured to inhibit the supply of electrical power from a source of electrical power if certain predetermined conditions are not met.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: April 2, 2024
    Assignee: American Axle & Manufacturing, Inc.
    Inventors: Mattias Freiholtz, Tommy Elbing, Alexander Tylee-Birdsall, David Kelly, John Burke, Jason Allen, Thomas Bengtsson, Michael Klinth
  • Publication number: 20240042116
    Abstract: Embodiments of the invention pertain to cartridges, systems and methods for performing hemodialysis and related extracorporeal blood treatment modalities and therapies, in which blood flows in the inter fiber space and dialysate flows in the lumens of hollow fibers. Appropriate connectors and fitting orientations may be provided. There may be provided orbital distributors, fanning of fibers, and features to promote uniformity of fiber spacing in the fiber bundle. Orbital distributors may contain contoured surfaces, flow redirectors, non-uniform-conductance flow elements, through-wall distributors, and other features. There may be subdivision of the fiber bundle into two groups of fibers with separate control fluid to each group. Appropriate systems may be provided for various therapies. Flow past the fibers may be parallel, transverse or other configuration.
    Type: Application
    Filed: April 10, 2023
    Publication date: February 8, 2024
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Thomas Kelly, Peter Materna
  • Publication number: 20230404507
    Abstract: A system for measuring muscle mass of a patient has a dual-energy radiation emission source. A radiation detector is configured to detect radiation emitted from the dual-energy radiation emission source passed through the patient. A processor has a memory with storing instructions, that when executed by the processor, perform a set of operations. The operations include receiving radiation detection data; generating a scan representation; identifying a primary fat target; determining an amount of fat in the primary fat target; comparing the amount of fat in the primary fat target to a reference; and based on the comparison, correcting an estimated amount of lean tissue to generate a corrected muscle mass value.
    Type: Application
    Filed: June 20, 2023
    Publication date: December 21, 2023
    Applicant: Hologic, Inc.
    Inventors: Kevin WILSON, Thomas KELLY
  • Publication number: 20230384511
    Abstract: A hollow core optical waveguide comprises a hollow core; and a structured arrangement of longitudinally extending capillaries surrounding the hollow core to form a cladding; wherein one or both of the hollow core and the cladding contains gas configured to provide a refractive index difference between the hollow core and the cladding.
    Type: Application
    Filed: September 2, 2021
    Publication date: November 30, 2023
    Inventors: Natalie WHEELER, Peter HORAK, Francesco POLETTI, Thomas KELLY, Matthew PARTRIDGE
  • Patent number: 11751354
    Abstract: A computing equipment box assembly can include a chassis base and a tray. The chassis base can include a bottom panel, an opening through the bottom panel, and a rim defined around the opening. The tray can include a body configured for supporting computing components, a frame section of the body sized to be supported atop the rim of the chassis base; and a downwardly embossed portion of the body extending downwardly from the rim and sized to fit within the opening of the chassis base when the frame section is supported atop the rim of the chassis base.
    Type: Grant
    Filed: June 25, 2021
    Date of Patent: September 5, 2023
    Assignee: Amazon Technologies, Inc.
    Inventors: Noah Thomas Kelly, Ryan F. Conroy, Christopher Mario Gil, Ali Elashri, Munish Sharma
  • Publication number: 20230266281
    Abstract: A high-duty-cycle liquid chromatography system that includes two or more columns that are configured to alternatingly be in a productive phase or a regeneration phase, wherein simultaneously one of the columns is in a productive phase and the other columns are in the regeneration phase. Additionally, the system includes a mobile phase gradient delivery pump, an isocratic pump, two or more gradient storage chambers, and two or more valves that are each independently coupled to a column and a gradient storage chamber. The column in the productive phase has a solution containing a sample which is pushed through the column, collected at a detector, and analyzed. The column in the regeneration phase is being prepared for the next productive phase.
    Type: Application
    Filed: February 24, 2023
    Publication date: August 24, 2023
    Inventors: Xiaofeng Xie, Ryan Thomas Kelly
  • Patent number: 11717244
    Abstract: A system for measuring muscle mass of a patient has a dual-energy radiation emission source. A radiation detector is configured to detect radiation emitted from the dual-energy radiation emission source passed through the patient. A processor has a memory with storing instructions, that when executed by the processor, perform a set of operations. The operations include receiving radiation detection data; generating a scan representation; identifying a primary fat target; determining an amount of fat in the primary fat target; comparing the amount of fat in the primary fat target to a reference; and based on the comparison, correcting an estimated amount of lean tissue to generate a corrected muscle mass value.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: August 8, 2023
    Assignee: Hologic, Inc.
    Inventors: Kevin Wilson, Thomas Kelly
  • Publication number: 20230180669
    Abstract: A method for producing a biodegradable floral arrangement media that includes obtaining a pre-formed mixture by mixing together: (a) a matrix of natural or inert inorganic fibers and/or powders; (b) a water insoluble, meltable compostable binder; and (c) optionally, additives; and heating the pre-formed mixture to fuse the binder with the matrix. Also, a biodegradable floral arrangement media made by the process, which is preferably compostable.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 15, 2023
    Inventors: Paul Thomas KELLY, Sang Hyen PARK, Gary LEGNANI
  • Patent number: 11654221
    Abstract: A dialysis fluid system includes a dialysis fluid inlet; a dialysis fluid outlet; a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the a dialysis fluid outlet, a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding fluid to heat.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: May 23, 2023
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din
  • Patent number: 11648341
    Abstract: Embodiments of the invention pertain to cartridges, systems and methods for performing hemodialysis and related extracorporeal blood treatment modalities and therapies, in which blood flows in the inter fiber space and dialysate flows in the lumens of hollow fibers. Appropriate connectors and fitting orientations may be provided. There may be provided orbital distributors, fanning of fibers, and features to promote uniformity of fiber spacing in the fiber bundle. Orbital distributors may contain contoured surfaces, flow redirectors, non-uniform-conductance flow elements, through-wall distributors, and other features. There may be subdivision of the fiber bundle into two groups of fibers with separate control fluid to each group. Appropriate systems may be provided for various therapies. Flow past the fibers may be parallel, transverse or other configuration.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: May 16, 2023
    Assignee: Novaflux Inc.
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin, Thomas Kelly, Peter Materna
  • Publication number: 20220225957
    Abstract: A dual-energy X-ray absorptiometry (“DXA”) system includes an x-ray source assembly comprising a source carriage to move the x-ray source assembly along a scan path, the scan path comprising an active scan portion and a reference measurement portion. A detector assembly including a detector carriage to move the detector assembly with the source assembly and to collect scan data at active scan portions. A support structure supporting the source and detector assemblies. A calibration controller coupled a calibration element having a known x-ray attenuation value and configured position the calibration element between the source and detector assemblies during the reference measurement portion and to remove the calibration element from between the source and detector assemblies during the active scan portion. A processing unit operable to compare the reference measurement against an expected reference value to identify a variance and to selectively trigger an action in response to the variance.
    Type: Application
    Filed: May 20, 2020
    Publication date: July 21, 2022
    Applicant: HOLOGIC, INC.
    Inventors: Thomas KELLY, Kevin WILSON, Mark GUETERSLOH, Wei WANG
  • Publication number: 20220211365
    Abstract: A tissue repair apparatus includes a housing, a rotatable shaft at least partially disposed within the housing, and first and second curved needles coupled to the shaft. The housing defines a gap between a first edge of the housing and a second edge of the housing, the gap adapted to receive tissue. The first and second needles curved needles being articulable within the housing from a delivery position, at which the first and second needles are spaced from the gap, to a deployed position, at which the first and second needles extend through the gap. Actuation of the shaft simultaneously articulates the first and second needles and the first needle enters the gap before the second needle enters the gap.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Inventors: William Thomas Kelly, Manoj Kumar Singh
  • Patent number: 11318248
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit with an improved reservoir heating system. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a reservoir with an internal pan and external pan, separated by a space that holds a heating element. The heating element is electrically coupled to electrical contacts attached to the external surface of the external pan.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: May 3, 2022
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, Alec Huang, Brian Thomas Kelly, Tam Nolan
  • Patent number: 11284879
    Abstract: A tissue repair apparatus includes a housing, a rotatable shaft at least partially disposed within the housing, and first and second curved needles coupled to the shaft. The housing defines a gap between a first edge of the housing and a second edge of the housing, the gap adapted to receive tissue. The first and second needles curved needles being articulable within the housing from a delivery position, at which the first and second needles are spaced from the gap, to a deployed position, at which the first and second needles extend through the gap. Actuation of the shaft simultaneously articulates the first and second needles and the first needle enters the gap before the second needle enters the gap.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: March 29, 2022
    Assignee: Howmedica Osteonics Corp.
    Inventors: William Thomas Kelly, Manoj Kumar Singh
  • Publication number: 20220092117
    Abstract: A system and method for determining the extent of beneficial ownership of a target business by populating a database structure wherein businesses and ownership relationships between the business are represented by nodes and links. Steps include querying the database to establish the related ownership links; analyzing results of the query to determine ownership loops; de-looping the ownership relationships; and calculating the percentage ownership of each of the beneficial owners of the target business based on de-looped ownership relationships. A computer readable non-transitory storage medium stores instructions of a computer program, which when executed by a computer system results in performance of steps of the method. A system architecture having features uniquely suited to the task is also disclosed.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Applicant: THE DUN & BRADSTREET CORPORATION
    Inventors: Stuart SWINDELL, Yunhong LIU, Thomas KELLY, Paul WESTCOTT
  • Patent number: 11222073
    Abstract: A system and method for determining the extent of beneficial ownership of a target business by populating a database structure wherein businesses and ownership relationships between the business are represented by nodes and links. Steps include querying the database to establish the related ownership links; analyzing the query to determine ownership loops; de-looping the ownership relationships; and calculating the percentage ownership of each of the beneficial owners of the target business based on de-looped ownership relationships. A computer readable non-transitory storage medium stores instructions of a computer program, which when executed by a computer system results in performance of steps of the method. A system architecture having features uniquely suited to the task is also disclosed.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: January 11, 2022
    Assignee: THE DUN AND BRADSTREET CORPORATION
    Inventors: Stuart Swindell, Yunhong Liu, Thomas Kelly, Paul Westcott
  • Patent number: 11223530
    Abstract: In an approach for extracting natural language text from a native device configuration of a network device, a processor converts a native device configuration of a network device to a standard element document. A processor extracts natural language text from the standard element document based on a set of predefined expressions. A processor extracts named entities from the extracted natural language text, according to given categories, via named-entity recognition. A processor maps each of the extracted and categorized named entities to a respective network device, based on respective extraction origin.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: January 11, 2022
    Assignee: International Business Machines Corporation
    Inventors: Ryan Goldblatt, Michael Maclynn, Keith Quinn, Stephen Thomas Kelly, Andrew T. Penrose
  • Patent number: 11187572
    Abstract: A load suspension and weighing system for a removable reservoir unit of a portable dialysis machine includes a centrally located flexure assembly. The flexure assembly includes magnets and a number of flexure rings which allow for movement of the magnets about a fixed circuit board. Sensors in the circuit board sense changes in the magnetic field as the magnets move in relation to the circuit board. The magnetic field changes produce a voltage output which is used by a processor to generate weight calculations. The top of the flexure assembly is attached to the interior of the dialysis machine. The entirety of the reservoir unit is suspended by a first internal frame that is attached to the bottom of the flexure assembly. Having a single flexure assembly positioned above the reservoir unit provides more accurate weight measurements while also preventing damage to the assembly from water spillage.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: November 30, 2021
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, Joe Fazio, Alec Huang, Brian Thomas Kelly, Tam Nolan, Mark Smith