Abstract: In an approach to fabricating a silicon on insulator wafer, one or more semiconductor device elements are implanted and one or more shallow trench isolations are formed on a top surface of a first semiconductor wafer. A first dielectric material layer is deposited over the top surface of the first semiconductor wafer, filling the shallow trench isolations. A dielectric material layer on a bottom surface of a second semiconductor wafer is bonded to a dielectric material layer on the top of the first semiconductor wafer and one or more semiconductor devices are formed on a top surface of the second semiconductor wafer. Then, one or more through silicon vias are created connecting the one or more semiconductor devices on the top surface of the second semiconductor wafer and the one or more semiconductor device elements on the top surface of the first semiconductor wafer.

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (A), (ii) at least one mixing section (B), and (iii) a discharging section (E), wherein the processing element(s) defining the mixing section (B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw type element (FIG. 2).

Abstract: Extruded nutritional powders and methods of manufacturing the extruded nutritional powders, including extruded infant nutritional powders and extruded adult nutritional powders are provided. The processes utilize an extruder that is capable of internally mixing and emulsifying protein, and optionally, a carbohydrate with fat and water into an emulsion that can be dried into a powder having equivalent fat separation and dispersibility as compared to spray dried powders.

Abstract: A method of producing an emulsion and an extrudate for a powdered nutritional product is provided. The method includes utilizing an extruder (10) that contains a high shear element (32) positioned within the barrel of the extruder (20). The use of a high shear element (32) positioned within the barrel of the extruder (20) allows both emulsification and extrusion of the ingredients to occur within the barrel of the extruder (20). A first portion of ingredients comprising a slurry is processed by the high shear element (32) to form an emulsion. The emulsion is then combined with a second portion of ingredients and extruded to form an extrudate for the desired powdered nutritional product. In some embodiments, the high shear element (32) may comprise a shearing disc or a pair of shearing discs. The extruder (10) may comprise a single screw extruder, a twin screw extruder, or any other suitable type of extruder.

Abstract: The present disclosure relates to solid dosage forms comprising antiviral compounds and methods of using such dosage forms to treat antiviral infection.

Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 (or a pharmaceutically acceptable salt thereof), Compound 2 (or a pharmaceutically acceptable salt thereof), and ritonavir (a pharmaceutically acceptable salt thereof), which are co-formulated in amorphous solid dispersion comprising a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant.

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (A), (ii) at least one mixing section (B), and (iii) a discharging section (E), wherein the processing element(s) defining the mixing section (B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw type element (FIG. 2).

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (R; A), (ii) at least one reverse-flight section (D), and (iii) a discharging section (E), wherein the processing elements defining the reverse-flight section (R; D) comprise at least one reverse-flight element (14) which is based on a screw-type element having a conveying direction being opposite to the general conveying direction of the extruder.

Abstract: The present invention relates to a process for producing monolithic tablets. The method employs a melt-processed composition containing at least on active agent and at least one thermoplastic binder. The invention further relates to a method for cutting and deflashing a belt of pre-shaped bodies of a melt-processed composition, wherein the pre-shaped bodies are interconnected by flash.

Abstract: A lined beverage-cooling container is disclosed, the container comprises a carton lined with a watertight liner bag. The walls of the bag are higher than the walls of the carton. Because the bag expands past the walls of the carton, a cavity for holding ice is formed on top of the carton. A method of use such container is also disclosed.

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (A), (ii) at least one mixing section (B), and (iii) a discharging section (E), wherein the processing element(s) defining the mixing section (B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw type element (FIG. 2).

Abstract: A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (R; A), (ii) at least one reverse-flight section (D), and (iii) a discharging section (E), wherein the processing elements defining the reverse-flight section (R; D) comprise at least one reverse-flight element (14) which is based on a screw-type element having a conveying direction being opposite to the general conveying direction of the extruder.

Abstract: Systems and techniques for integrating information for the planning and performance of maintenance activities are described. In one aspect, a method includes receiving a collection of descriptions of maintenance tasks in an enterprise, accessing one or more data stores to receive asset information characterizing assets in the enterprise, process information characterizing assets involved in processes of the enterprise, and process value information characterizing values of the processes to the enterprise, integrating the asset information, the process information, and the process value information to assign costs associated with performance of each of the maintenance tasks, generating a work list including a subset of the collection of maintenance tasks based on the assigned costs, and making the work list available over one or more output devices.

Abstract: Solid mixtures of a reactive size and starch, which are obtainable by mixing at least one reactive size with at least one starch in a melt in the presence of at least one destructuring agent for starch under the action of shear forces at from 65 to 250° C. and cooling the melt to room temperature, are used in the form of aqueous dispersions as process assistants in papermaking.

Abstract: An in-space spacecraft servicing system (10) includes a servicing spacecraft (22) and a propellant module (24). The servicing spacecraft includes a client servicing system (136), as well as navigation avionics (108) for independent flight operation and a servicing propellant tank (170). The propellant module moves the servicing module from an upper stage drop off location and releases it in proximity to a client spacecraft (16) for a servicing mission. It has a propellant tank (172) with capacity for multiple missions and is used to refill the servicing spacecraft's propellant tanks between missions. Either or both the servicing spacecraft and the propellant module may have navigation avionics. The servicing spacecraft also has a universal docking adaptor (70) for different client spacecraft, and can convert a client spacecraft from non-cooperative to cooperative.

Abstract: An in-space spacecraft servicing system (10) includes a servicing spacecraft (22) and a propellant module (24). The servicing spacecraft includes a client servicing system (136), as well as navigation avionics (108) for independent flight operation and a servicing propellant tank (170). The propellant module moves the servicing module from an upper stage drop off location and releases it in proximity to a client spacecraft (16) for a servicing mission. It has a propellant tank (172) with capacity for multiple missions and is used to refill the servicing spacecraft's propellant tanks between missions. Either or both the servicing spacecraft and the propellant module may have navigation avionics. The servicing spacecraft also has a universal docking adaptor (70) for different client spacecraft, and can convert a client spacecraft from non-cooperative to cooperative.

Abstract: A pipe joiner includes a power assembly and first and second attachment retainers, each retainer configured to accept a pipe claw. A frame supports the first and second attachment retainers. The power assembly is coupled to the frame in such a manner that operating the power assembly draws the retainers toward one another.

Abstract: Systems and techniques for debugging machine-readable instructions are described. In one implementation, a method includes receiving an identification of a debugger, identifying an activated business software module that is to be debugged, receiving a change to the instructions of the business software module, establishing a second version of the business software module that includes the change, and activating the second version for the debugger while the business software module remains activated. The business software module is an individually functional set of machine-readable instructions operable to integrate and manage operations of a business.

Abstract: Alkylketene dimers are prepared by reacting acyl chlorides with tertiary amines in a molar ratio of from 1:1 to 1:1.6 at from 65 to 150° C. and with a residence time of from 1 to 30 minutes in the absence of solvents with thorough mixing and isolation of the alkylketene dimers.

Abstract: An air outlet device (1) for vehicles, in particular airplanes, comprises a panel (2) with at least one receiving opening, an air outlet (3) arranged in the receiving opening, and a sealing means (6) sealing the air outlet (3) and the panel (2) against each other. At the panel (2) and/or the air outlet (3), a securing means (8) is configured, it serves to mount the air outlet (3) to the panel (2). During the assembly of the air outlet device (1), the securing means (8) holds the air outlet (3) in a defined position in the panel (2) so that curing adhesives can be used as sealing means (6) without any problem.