Abstract: The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

Abstract: This disclosure relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment of the patient can be interrupted with the intention to continue the blood treatment. This disclosure further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

Abstract: There are provided, inter alia, compositions and methods for treatment of chemoresistant cancer (breast cancer). The methods include administering to a subject in need a therapeutically effective amount of a chemotherapeutic agent and a ROR-1 antagonist. Further provided are pharmaceutical compositions including chemotherapeutic agent, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the chemotherapeutic agent is paclitaxel and the ROR-1 antagonist is cirmtuzumab.

Abstract: An air supply system for a rail vehicle that includes electrical consumers, such as a compressor, an air dryer, a valve or the like, and a converter coupled to a power supply of the rail vehicle, wherein the air supply system adjusts the voltage provided by the power supply to an operating voltage of at least one electrical consumer, wherein the converter is associated with at least two of the plurality of electrical consumers in such a way that the converter can control, particularly in a closed-loop manner, and/or monitor the operation of the at least two of the plurality of electronic consumers.

Abstract: The invention relates to a drain valve for a cooler of a compressor, with a pressure chamber which can be connected to the inner chamber of the cooler by means of a connection opening, and an outlet for removing a condensate. The valve according to the invention comprises a pneumatic switching device and a non-return valve which are operatively connected to the pressure chamber, with an operative connection between the switching device and the non-return valve by means of which the non-return valve can be switched to an open position by the switching device. During the idle operation of the compressor, the non-return valve can be switched by means of the switching device into an open position such that condensate from the connection opening can be removed through the outlet via the non-return valve.

Abstract: A piston compressor includes at least one cylinder for compressing air with a piston arranged such that it can move therein in a compression chamber arranged above the piston in the cylinder. The compression chamber is connected to an inlet arrangement for air to be compressed and to an outlet arrangement for compressed air, the piston compressor being drivable by a first drive device. The inlet arrangement includes a pre-compression device that can be driven by a second drive device with variable power and is used to increase the suction pressure at the air inlet.

Abstract: There are provided, inter alia, compositions and methods for treatment of chemoresistant cancer (breast cancer). The methods include administering to a subject in need a therapeutically effective amount of a chemotherapeutic agent and a ROR-1 antagonist. Further provided are pharmaceutical compositions including chemotherapeutic agent, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the chemotherapeutic agent is paclitaxel and the ROR-1 antagonist is cirmtuzumab.

Abstract: The invention relates to a drain valve for a cooler of a compressor, with a pressure chamber which can be connected to the inner chamber of the cooler by means of a connection opening, and an outlet for removing a condensate. The valve according to the invention comprises a pneumatic switching device and a non-return valve which are operatively connected to the pressure chamber, with an operative connection between the switching device and the non-return valve by means of which the non-return valve can be switched to an open position by the switching device. During the idle operation of the compressor, the non-return valve can be switched by means of the switching device into an open position such that condensate from the connection opening can be removed through the outlet via the non-return valve.

Abstract: A rail vehicle compressor system and method for controlling the same uses a compressor driven by an electrical machine via a drive shaft to produce compressed air for at least one compressed air tank, wherein the electrical machine can be activated at least indirectly via a control device for operating the electrical machine at at least one speed between a maximum speed and a minimum speed, wherein at least one pressure sensor determines the pressure for the control device and a final control element continuously influences the speed of the electrical machine, wherein activation of the final control element takes place via the control device in accordance with a sensor device, comprising at least one sensor element for sensing at least one external boundary condition of the rail vehicle.

Abstract: A rail vehicle compressor system comprises a compressor, driven by an electrical machine via a drive shaft, for producing compressed air for at least one compressed air tank. The electrical machine is activated at least indirectly via a control device for operating the electrical machine at least one nominal speed between a maximum speed and a minimum speed. At least one pressure sensor determines the pressure for the control device and is disposed in a compressed-air-carrying line downstream of the compressor. A final control element for continuously influencing the speed of the electrical machine is disposed between an electrical supply and the electrical machine, wherein the control device controls activation of the final control element. A method for controlling the compressor system is also provided, wherein, the compressor is operated at a variable speed in between the maximum speed and the minimum speed based on rail vehicle operating state.

Abstract: A piston compressor includes at least one cylinder for compressing air with a piston arranged such that it can move therein in a compression chamber arranged above the piston in the cylinder. The compression chamber is connected to an inlet arrangement for air to be compressed and to an outlet arrangement for compressed air, the piston compressor being drivable by a first drive device. The inlet arrangement includes a pre-compression device that can be driven by a second drive device with variable power and is used to increase the suction pressure at the air inlet.

Abstract: A compressed air supply device for a rail vehicle, having a main compressor for generating compressed air for a pneumatic brake system and a vehicle battery for supplying electric energy. The compressed air generator for supplying additional auxiliary air for operating at least one pneumatic actuator is provided in a frame of an adjusting drive for a pantograph. The compressed air generator for supplying auxiliary air includes an electric frequency converter for operating the electric-motor driven main compressor of the rail vehicle with low rotational speed from the electric drive energy provided by the vehicle battery. A secondary line is attached to the compressed air line connected to the main compressor to branch off the auxiliary air for the supply of auxiliary air of the actuator.

Abstract: A method and device for regeneration of an adsorption air dryer having at least two desiccant-filled drying vessels connected in parallel, wherein a humid compressed-air stream generated by a compressor flows through one of the drying vessels in a drying phase and a dry compressed-air stream flows through the other drying vessel, for the purpose of dewatering the desiccant, in a simultaneous regeneration phase, wherein a valve arrangement is provided for switching the drying vessels alternately between drying phase and regeneration phase during normal operation, wherein the control mechanism are provided for implementing a post-regeneration phase, which control mechanism initiates a further flow through the drying vessel with dry compressed air for complete regeneration and also a flow through the other drying vessel; with dry compressed air for complete regeneration, so that, upon the next start of operation of the adsorption air dryer, operation commences with fully regenerated drying vessels.

Abstract: A rail vehicle compressor system and method for controlling the same use a compressor driven by an electrical machine via a drive shaft, to produce compressed air for at least one compressed air tank, wherein the electrical machine can be activated at least indirectly via a control device for operating the electrical machine at at least one nominal speed between a maximum speed and a minimum speed, wherein at least one pressure sensor determines the pressure for the control device and is disposed in a compressed-air-carrying line downstream of the compressor. A final control element continuously influences the speed of the electrical machine and can be activated via the control device, and wherein a pressure switch for monitoring the pressure in the at least one compressed air tank and for influencing at least the speed of the electrical machine is disposed in the compressed-air-carrying line downstream of the compressor.

Abstract: A rail vehicle compressor system and method for controlling the same uses a compressor driven by an electrical machine via a drive shaft to produce compressed air for at least one compressed air tank, wherein the electrical machine can be activated at least indirectly via a control device for operating the electrical machine at at least one speed between a maximum speed and a minimum speed, wherein at least one pressure sensor determines the pressure for the control device and a final control element continuously influences the speed of the electrical machine, wherein activation of the final control element takes place via the control device in accordance with a sensor device, comprising at least one sensor element for sensing at least one external boundary condition of the rail vehicle.

Abstract: A rail vehicle compressor system comprises a compressor, driven by an electrical machine via a drive shaft, for producing compressed air for at least one compressed air tank. The electrical machine is activated at least indirectly via a control device for operating the electrical machine at at least one nominal speed between a maximum speed and a minimum speed. At least one pressure sensor determines the pressure for the control device and is disposed in a compressed-air-carrying line downstream of the compressor. A final control element for continuously influencing the speed of the electrical machine is disposed between an electrical supply and the electrical machine, wherein the control device controls activation of the final control element. A method for controlling the compressor system is also provided, wherein, the compressor is operated at a variable speed in between the maximum speed and the minimum speed based on rail vehicle operating state.

Abstract: A compressed air supply device for a rail vehicle, having a main compressor for generating compressed air for a pneumatic brake system and a vehicle battery for supplying electric energy. The compressed air generator for supplying additional auxiliary air for operating at least one pneumatic actuator is provided in a frame of an adjusting drive for a pantograph. The compressed air generator for supplying auxiliary air includes an electric frequency converter for operating the electric-motor driven main compressor of the rail vehicle with low rotational speed from the electric drive energy provided by the vehicle battery. A secondary line is attached to the compressed air line connected to the main compressor to branch off the auxiliary air for the supply of auxiliary air of the actuator.

Abstract: A method and device for regeneration of an adsorption air dryer having at least two desiccant-filled drying vessels connected in parallel, wherein a humid compressed-air stream generated by a compressor flows through one of the drying vessels in a drying phase and a dry compressed-air stream flows through the other drying vessel, for the purpose of dewatering the desiccant, in a simultaneous regeneration phase, wherein a valve arrangement is provided for switching the drying vessels alternately between drying phase and regeneration phase during normal operation, wherein the control mechanism are provided for implementing a post-regeneration phase, which control mechanism initiates a further flow through the drying vessel with dry compressed air for complete regeneration and also a flow through the other drying vessel; with dry compressed air for complete regeneration, so that, upon the next start of operation of the adsorption air dryer, operation commences with fully regenerated drying vessels.