Patents by Inventor Thomas Klauser

Thomas Klauser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacteria for preparing stable fusion proteins and methods for detecting the same
    Patent number: 6040141
    Abstract: The present invention relates to bacteria for preparing stable fusion prons from a carrier protein and a passenger protein, the bacteria possessing the genetic marker fpt. This genetic marker permits the improved preparation of protein fusions having a destabilizing effect on bacteria. The present invention in particular relates to bacteria for preparing fusion proteins, the bacteria stably presenting the fusion proteins on their surface and possessing the markers ompT.sup.-- and dsbA.sup.-- in addition to the genetic marker fpt. Moreover, the present invention relates to the identification of bacteria, which present heterologous proteins having an affinity to a binding partner on its surface and methods for constructing vectors encoding these proteins. Finally, the present invention also relates to bacteria which stably present at least one fusion protein on their surface and possess the genetic markers fpt, ompT.sup.-- and dsbA.sup.--, and their use for instance for diagnostic purposes.
    Type: Grant
    Filed: September 23, 1996
    Date of Patent: March 21, 2000
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Thomas Klauser, Joachim Kramer, Thomas F. Meyer, Johannes Pohlner