Patents by Inventor Thomas Klopack

Thomas Klopack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarker detection in circulating cells
    Patent number: 7537938
    Abstract: A method is provided for detecting biomarkers in rare circulating cells by forming an enriched population of cells immunomagnetically followed by biomarker detection using binding compounds having releasable molecular tags. Preferably, biomarkers comprising one or more protein-protein complexes are detected in circulating cancer cells metastasized from a solid tumor. In the presence of biomarkers, the molecular tags of the binding compounds are released and separated from the assay mixture for detection and/or quantification.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: May 26, 2009
    Assignee: Monogram Biosciences, Inc.
    Inventors: Hrair Kirakossian, Thomas Klopack, Sharat Singh
  • Biomarker detection in circulating cells
    Publication number: 20040157271
    Abstract: A method is provided for detecting biomarkers in rare circulating cells by forming an enriched population of cells immunomagnetically followed by biomarker detection using binding compounds having releasable molecular tags. Preferably, biomarkers comprising one or more protein-protein complexes are detected in circulating cancer cells metastasized from a solid tumor. In the presence of biomarkers, the molecular tags of the binding compounds are released and separated from the assay mixture for detection and/or quantification.
    Type: Application
    Filed: January 26, 2004
    Publication date: August 12, 2004
    Inventors: Hrair Kirakossian, Thomas Klopack, Sharat Singh