Patents by Inventor Thomas Koblizek

Thomas Koblizek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210324367
    Abstract: Disclosed is a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied. Also disclosed is a device 58 comprising at least three electrodes 63, 64, which are connected to at least one voltage source by means of at least one switching device 59, 60, 61, 62, wherein at least five electrodes 63, 64 are connected to the at least one voltage source by means of four switching devices 59, 60, 61, 62, wherein at least two electrodes 63, 64 are connected to the voltage source by means of a common switching device 59, 60, 61, 62.
    Type: Application
    Filed: May 5, 2021
    Publication date: October 21, 2021
    Applicant: Lonza Cologne GmbH
    Inventors: Thomas Koblizek, Andreas HEINZE, Timo GLEISSNER, Herbert Mueller-Hartmann, Andreas WIRTH
  • Patent number: 11021698
    Abstract: Disclosed is a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied. Also disclosed is a device 58 comprising at least three electrodes 63, 64, which are connected to at least one voltage source by means of at least one switching device 59, 60, 61, 62, wherein at least five electrodes 63, 64 are connected to the at least one voltage source by means of four switching devices 59, 60, 61, 62, wherein at least two electrodes 63, 64 are connected to the voltage source by means of a common switching device 59, 60, 61, 62.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: June 1, 2021
    Assignee: LONZA COLOGNE GMBH
    Inventors: Thomas Koblizek, Andreas Heinze, Timo Gleissner, Herbert Mueller-Hartmann, Andreas Wirth
  • Publication number: 20170306317
    Abstract: Disclosed is a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied. Also disclosed is a device 58 comprising at least three electrodes 63, 64, which are connected to at least one voltage source by means of at least one switching device 59, 60, 61, 62, wherein at least five electrodes 63, 64 are connected to the at least one voltage source by means of four switching devices 59, 60, 61, 62, wherein at least two electrodes 63, 64 are connected to the voltage source by means of a common switching device 59, 60, 61, 62.
    Type: Application
    Filed: May 11, 2017
    Publication date: October 26, 2017
    Inventors: Thomas Koblizek, Andreas Heinze, Timo Gleissner, Herbert Mueller-Hartmann, Andreas WIRTH
  • Patent number: 9701954
    Abstract: The invention relates to a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: July 11, 2017
    Assignee: LONZA COLOGNE GMBH
    Inventors: Thomas Koblizek, Andreas Heinze, Timo Gleissner, Herbert Mueller-Hartmann, Andreas Wirth
  • Publication number: 20130230895
    Abstract: The invention relates to a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied.
    Type: Application
    Filed: June 21, 2011
    Publication date: September 5, 2013
    Applicant: LONZA COLOGNE GMBH
    Inventors: Thomas Koblizek, Andreas Heinze, Timo Gleissner, Herbert Mueller-Hartmann, Andreas Wirth
  • Publication number: 20070269378
    Abstract: Human NADK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morpho-genesis, comprising screening for agents that modulate the activity of NADK are provided.
    Type: Application
    Filed: June 18, 2004
    Publication date: November 22, 2007
    Applicant: EXELIXIS INC.
    Inventors: Gregory Plowman, Felix Karim, Candace Swimmer, Hinrich Habeck, Thomas Koblizek, Stefan Schulte-Merker, Ulrike Eisenmann, Gordon Stott, Torsten Trowe, Andreas Vogel, Joerg Odenthal, Jochen Scheel, Torsten Will, Yinsheng Jin, Lynn Bjerke, Timothy Heuer
  • Publication number: 20070003927
    Abstract: Human MAPK7 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MAPK7 are provided.
    Type: Application
    Filed: October 22, 2003
    Publication date: January 4, 2007
    Inventors: Gregory Plowman, Felix Karim, Candace Swimmer, Hinrich Habeck, Thomas Koblizek, Stefan Schulte-Merker, Ulrike Langheinrich, Gordon Stott, Torsten Trowe, Andreas Vogel, Joerg Heinrich, Jochen Scheel, Torsten Will, Yisheng Jin, Joanne Adamkewicz
  • Publication number: 20060257870
    Abstract: Human CDKL1 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of CDKL1 are provided.
    Type: Application
    Filed: October 22, 2003
    Publication date: November 16, 2006
    Inventors: Gregory Plowman, Felix Karim, Candace Swimmer, Hinrich Habeck, Thomas Koblizek, Stefan Schulte-Merker, Ulrike Langheinrich, Gordon Stott, Torsten Trowe, Andreas Vogel, Joerg Odenthal, Jochen Scheel, Torsten Will, Yisheng Jin, Bing Hai