Abstract: An image processing system and related method. The system comprises an input interface (IN) for receiving dark-field image data obtained from imaging of an object (OB) with an X-ray imaging apparatus (XI). A corrector module (CM) of the system (IPS) is configured to perform a correction operation to correct said dark-field image data for Compton scatter to obtain Compton-Scatter corrected image data. The so Compton scatter corrected image data is output by an output interface (OUT) of the system.

Abstract: A system and related method for signal processing. Interferometric projection data reconstructed into one or more images for a spatial distribution of a physical property of an imaged object. The interferometric projection data is derived from signals acquired by an X-ray detector (D), said signals caused by X-ray radiation after interaction of said X-ray radiation with an interferometer and with the object (OB) to be imaged, said interferometer (IF) having a reference phase. A reconstructor (RECON) reconstructs for the image(s) by fitting said data to a signal model by adapting fitting variables, said fitting variables including i) one or more imaging variables for the one or more images and ii), in addition to said one or more imaging variables, a dedicated phase variable for a fluctuation of said reference phase.

Abstract: A component (XS) for an X-ray detector device (XD), comprising a layer (SL) tessellated in a plurality of different regions (Rj), the regions having respective periodic structures at a respective phase, wherein two neighboring regions have periodic structures at different phases.

Abstract: The present invention relates to an apparatus (10) for presentation of dark field information. It is described to provide (210) an X-ray attenuation image of a region of interest of an object. A dark field X-ray image of the region of interest of the object is also provided (220). A plurality of sub-regions of the region of interest are defined (230) based on the X-ray attenuation image of the region of interest or based on the dark field X-ray image of the region of interest. At least one quantitative value is derived (240) for each of the plurality of sub-regions, wherein the at least one quantitative value for a sub-region comprises data derived from the X-ray attenuation image of the sub-region and data derived from the dark field X-ray image of the sub-region. A plurality of figures of merit are assigned (250) to the plurality of sub-regions, wherein a figure of merit for a sub-region is based on the at least one quantitative value for the sub-region.

Abstract: The present invention relates to a device for anodized oxidation of an anode element for a curved X-ray grating, the device (10) comprising: an anode element (12); a cathode element (14); an electrolytic medium (16); a conductor element (18); and a carrier element (20); wherein the anode element (12) comprises a first side (11) and a second side (13), wherein the second side (13) faces opposite to the first side (11); wherein the carrier element (20) comprises a curved surface section (21) that extends along a curvature around a center of curvature (30); wherein the carrier element (20) is configured to receive the second side (13) of the anode element (12) for attaching the conductor element (18) to the first side (11) of the anode element (12); wherein the curved surface section (21) is configured to receive the conductor element (18) after detaching the second side (13) of the anode element (12) from the carrier element (20); wherein the electrolytic medium (16) is configured to connect the anode element (

Abstract: The present invention relates to a device (100) for denoising a vector-valued image, the device (100) comprising: a generator (10), which is configured to generate an initial loss function (L_I) comprising at least one initial covariance matrix (ICM) defining a model of correlated noise for each pixel of the vector-valued image; a processor (20), which is configured to provide a final loss function (L_F) comprising a set of at least one final covariance matrix (FCM) based on the initial loss function by modifying at least one submatrix and/or at least one matrix element of the initial covariance matrix (ICM); and a noise-suppressor (30), which is configured to denoise the vector-valued image using the final loss function (L_F) comprising the set of the at least one final covariance matrix (FCM).

Abstract: A source grating structure (G0) for interferometric X-ray imaging cable of generating a non-uniform intensity profile behind a surface (S) of the grating structure when exposed to X-ray radiation.

Abstract: A method for displaying a pointer in an instrument panel is described. The method comprises retrieving a current instrument status of an instrument of the instrument panel that is to be displayed, determining a pointer form on the basis of the current instrument status, retrieving of the determined pointer form from a texture atlas, and rendering the pointer in the instrument panel with the retrieved pointer form. There is further described a device for displaying an instrument panel, which device comprises a display module configured to display at least one instrument panel having at least one pointer instrument, and a controller configured to carry out the method using the display module. A vehicle having such a device is also disclosed.

Abstract: A computed tomography imaging system (102) includes an X-ray radiation source (110) configured to emit X-ray radiation that traverses an examination region (108) and an X-ray radiation sensitive detector array (112) configured to detect X-ray radiation traversing the examination region and generate a view of line integrals. The imaging system further includes a subject support table top (118) configured to translate in the examination region for a scan based on at least one scan parameter. The imaging system further includes an operator console (122), which includes a processor (128) and computer readable storage medium (130) with a scan parameter adapter module (132). The processor is configured to execute instructions of the scan parameter adapter module, which causes the processor to determine a contrast agent concentration from the view of line integrals and adjust the at least one scan parameter based on the determined concentration.

Abstract: A system includes a single backprojector (120), which includes a single geometry calculator (204), at least one weight calculator (206), and a plurality of data interpolators (208). The single geometry calculator is configured to process scan parameters of a single computed tomography scan to generate geometry values only once for each voxel position in a volumetric image data matrix. The at least one weight calculator is configured to process the scan parameters of the single computed tomography scan and the geometry values to generate weight values for each voxel position in the volumetric image data matrix. Each of the plurality of data interpolators is configured to process, using the weight values and the same geometry values, a respective different type of projection data produced from the same single computed tomography scan to generate volumetric image data based on the volumetric image data matrix and corresponding to the respective different type of projection data.

Abstract: A calibration method and corresponding object for calibrating an X-ray imaging system with respect to dark field imaging is disclosed. The calibration object (1) generically comprises a plurality of sections (10, 20), wherein at least a part of the sections comprises two different materials, respectively. One material (101, 201) in a corresponding section leads to attenuation of passing X-ray beams and the other material (102, 202) is a dark field active material leading to small-angle scattering signals of incident X-rays. The ratio of the two materials in one section varies from section to section. The calibration object can be used to calibrate an X-ray imaging system with respect to a non-linear behavior of the dark field visibility.

Abstract: A mobile system has a circuitry, which has a camera. The circuitry captures a plurality of images of a user's eye with the camera, determines based on at least one of the captured images of the eye, an image quality of at least one feature of the eye in the captured image, and outputs a user instruction for changing the image quality of the at least one feature of the eye.

Abstract: The present invention relates to a method, and a corresponding device, for testing a radius of curvature and/or for detecting inhomogeneities of a curved X-ray grating for a grating-based X-ray imaging device. The method comprises generating a beam of light diverging from a source point, propagating along a main optical axis and having a line-shaped beam profile. The method comprises reflecting the beam off a concave reflective surface of the grating. A principal axis of the concave reflective surface coincides with the main optical axis and the source point is at a predetermined distance from a point where the main optical axis intersects the concave reflective surface.

Abstract: The present invention relates to a device for aligning an X-ray grating to an X-ray radiation source, the device (10) comprising at least two flat X-ray grating segments (11-19); at least one alignment unit (31-39) for aligning one of the at least two flat X-ray grating segments; wherein the at least two flat X-ray grating segments (11-19) are arranged in juxtaposition and are forming an X-ray grating (20); wherein the at least two flat X-ray grating segments (11-19) each comprise a grating surface (41-49) for X-ray radiation, each grating surface (41-49) comprising a geometrical center; wherein normals (21-29) to each of the grating surfaces (41-49) define a common plane (73), wherein the normals (21-29) intersect the geometrical center of the grating surface (41-49); wherein at least a first of the at least two flat X-ray grating segments (11-19) is rotatable around an axis (131-139) that is perpendicular to the common plane (73); and wherein the first of the at least two flat X-ray grating segments (11-19)

Abstract: The present invention relates to an apparatus for X-ray imaging an object. It is described to provide (20) data relating to the detection of X-rays, wherein an X-ray detector is configured to be positioned relative to an X-ray source such that at least a part of a region between the X-ray source and the X-ray detector is an examination region for accommodating an object. An X-ray interferometer arrangement is configured to be positioned relative to the examination region. At least one X-ray dark field factor and at least one transmission factor are determined for the X-ray radiation transmitted through at least part of the object is determined. An intensity of X-ray radiation to be emitted towards the at least part of the object is controlled as a function of the determined at least one dark field factor and the determined at least one transmission factor.

Abstract: A beam hardening correction method, a related calibration method for tomographic image data and a related apparatus. The tomographic image data includes attenuation data (f) and phase gradient data (g) and/or small angle scattering data (h). A correction value is computed from the attenuation data (f) by applying a function (q) to the attenuation data (f). The correction value is combined (S445) with the phase gradient data (g) or with the small angle scattering data (h).

Abstract: A system (100) includes an imaging system (102) and a pressure delivery system (104). The imaging system includes a data acquisition system (114 and 116) and is configured to produce data. The pressure delivery system is configured to produce a periodic airflow variation. The system further includes an operator console (120) configured to control the imaging system to scan a subject receiving the periodic airflow variation and map the periodic airflow variation and first data. The system further includes a reconstructor (516) configured to reconstruct the first data and generate first volumetric image data indicative of the periodic airflow variation.

Abstract: The present invention relates to a device for reconstructing an X-ray tomography image, the device comprising a reconstruction module, which is configured to utilize an ordered subset maximum likelihood optimization with a diagonal paraboloid approximation of a cost function for the reconstructing of the X-ray tomography image; and a calculation module, which is configured to calculate a pre-computable denominator term for the cost function for a plurality of subsets of projection data based on a distribution of diagonal denominator terms over the plurality of the subsets of the projection data.

Abstract: The present invention is directed towards spectral imaging, wherein a dedicated spectral imaging phantom is scanned with a spectral x-ray device to obtain spectral imaging data of the spectral imaging phantom. Said imaging data of the spectral imaging phantom is used as input for obtaining improved further imaging data of a subject of which a spectral scan is performed subsequent to or simultaneous with the spectral scan of the spectral imaging phantom. Improved further imaging data may be obtained by using the spectral phantom imaging data as input for imaging data correction, for providing a recommendation and/or for further data processing.

Abstract: Provided herein are compounds that form covalent bonds with peptidases, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SPase), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.