Abstract: Methods for operating a medical imaging device for positionally correct representation of non-anatomical structures during an imaging examination may include providing a first 3D image containing at least one anatomical structure, extracting at least one anatomical model from the at least one anatomical structure, providing 2D update images recorded at different times, extracting non-anatomical and anatomical structures from subsets of the update images, calculating a non-anatomical 3D image from at least two partial reconstructions based on the extracted non-anatomical structures, reconstructing an anatomical 3D image based on the extracted anatomical structures, registering the anatomical 3D image with the first 3D image by determining a coordinate transformation, and creating a navigation volume from the anatomical model and the non-anatomical 3D image using the coordinate transformation.

Abstract: The present invention relates to the field of pharmacogenomics and in particular to detecting the presence or absence of methylated ANKRD13B and/or SEPTIN9 DNA derived from a tumor in blood or blood-derived samples or in other body fluids that contain DNA released from a tumor. This detection is useful for a minimally or non-invasive as well as early and reliable diagnosis of colorectal cancer. The invention provides methods and oligonucleotides suitable for this purpose.

Abstract: A method for setting the visibility of objects in a projection image generated by radiation of an anatomical region includes loading imaging data representing a projection image generated by radiation into a memory of a computer, generating a first partial image from the imaging data using a first semantic class by an artificial intelligence device executing an artificial intelligence algorithm, combining the first partial image and the imaging data to generate an output image using a first adjustable function with at least one first parameter such that the first function determines a rendering of the first partial image in the output image, displaying an output image on a display device; and generating training data for training the artificial intelligence algorithm of the artificial intelligence device.

Abstract: A method of registering two sets of medical image data taking into account scene changes can include providing a first and a second medical image data set by means of a medical device, subdividing the first and second medical image data sets into an equal number of sub-images, performing a number of individual registrations between the first and second medical image data sets with respective optimization of a similarity measure, identifying the sub-images that have a scene change, and performing a final registration between the first and the second medical image data set by masking out the identified sub-images or a masked out sub-image combination. For each individual registration, at least one sub-image of the first and/or second medical image data set can be masked out by means of a random process when determining the respective measure of similarity.

Abstract: An outlet nozzle (40) for a centrifuge bowl (60) comprises a nozzle insert (10) and a nozzle holder (30). The nozzle insert (10) can be exchangeably fixed, in particular clamped, in the nozzle holder (30), and the outlet nozzle (40) has a flow channel (11) which determines the exit angle (?) of the outlet nozzle (40), said flow channel (11) of the outlet nozzle (40) being formed, in particular, by the nozzle insert (10).

Abstract: A method of registering two sets of medical image data taking into account scene changes can include providing a first and a second medical image data set by means of a medical device, subdividing the first and second medical image data sets into an equal number of sub-images, performing a number of individual registrations between the first and second medical image data sets with respective optimization of a similarity measure, identifying the sub-images that have a scene change, and performing a final registration between the first and the second medical image data set by masking out the identified sub-images or a masked out sub-image combination. For each individual registration, at least one sub-image of the first and/or second medical image data set can be masked out by means of a random process when determining the respective measure of similarity.

Abstract: The present invention relates to a material handling and/or construction machine, in particular lifting gear such as a crane, comprising a plurality of electric drives for driving work assemblies and/or structural components of the material handling and/or construction machine, a control apparatus for controlling the drives, and a power supply device for supplying electric power to the electric drives, wherein the power supply device has a grid connection for connection to a power grid and drawing of the electric power from the power grid, wherein a measuring device for measuring the total electric power consumption of the material handling and/or construction machine from the power grid is provided at the grid connection at the machine-end grid connection.

Abstract: Method for providing a large-area x-ray image of an object mounted by means of an object platform and providing additional synthetic x-ray projections, comprising Recording of a plurality of x-ray projections by means of an x-ray device, wherein the plurality of x-ray projections are recorded during a linear movement of the object platform and/or the x-ray device; preparation of at least one tomographic volume from the plurality of x-ray projections; preparation of at least one first synthetic forward projection from the at least one tomographic volume, wherein the at least one synthetic forward projection yields a large-area x-ray image; representation of the large-area x-ray image on a suitable display device; selection and/or marking of an area of interest within the large-area x-ray image; preparation of at least one second synthetic forward projection comprising the area of interest; representation of the at least one second synthetic forward projection on a suitable display device; characterised in that

Abstract: A treatment module for a laundry treatment device includes a number of treatment brushes, which are each intended for contact with a laundry item to be treated. In order to organize a smoothing process in the most optimum possible way, each two treatment brushes form at least one pair and are disposed in a treatment position relative to one another or are able to be disposed in the treatment position, in which the treatment brushes of the at least one pair lie opposite one another so that, upon positioning of a laundry item between the treatment brushes of the at least one pair, they are in contact with both sides of the laundry item.

Abstract: Medical imaging systems and methods for determining contours of anatomical structures of vessels and vessel sections for representation in X-ray-based fluoroscopic images. Methods can include capturing a mask image, recording at least one filling image including a vascular tree filled with contrast agent, subtracting the mask image from the at least one filling image to produce at least one vessel image, generating a segmented vessel image by segmenting the vascular tree filled with contrast agent in the at least one vessel image and removing from the at least one segmented vessel image such vessels and vessel sections that do not meet a threshold value, wherein the threshold value represents a function of at least one predetermined structural feature, and superimposing the at least one segmented vessel image with a live X-ray image and reproduction on a display device.

Abstract: Medical imaging systems and methods for representing a 3D volume containing at least one foreign object introduced into a tissue. Imaging methods may include provision of a 3D volume containing voxels of at least one foreign object and voxels of tissue surrounding the at least one foreign object, identification of the voxels of the at least one foreign object by application of a processing rule, segmentation of the voxels of the at least one foreign object from the voxels of the tissue surrounding the at least one foreign object while maintaining the 3D volume, generation of a synthetic volume from a residual volume and the volume of the at least one foreign object, and representation of the synthetic volume on a display device using a windowing system.

Abstract: A pivot bearing (1), includes a metallic first bearing element (2) made of steel, which is at least partially coated by means of a coating (5), a metallic second bearing element (3) made of steel, which is coated with a PTFE-containing sliding lining (6), wherein the coating (5) and the sliding lining (6) are in sliding contact, and wherein the coating (5) comprises at least one first layer (9) deposited on the first bearing element (2) by means of a PVD, CVD, or PECVD method, wherein the coating (5) also comprises at least one further layer which is arranged on the at least one first layer (9) and faces away from the first bearing element (2).

Abstract: An extruder system for degassing a mixture, comprising a first extruder, a second extruder arranged downstream of the first extruder and a transfer zone formed between these extruders, characterized by a pressure regulating device which can regulate the pressure at the outlet of the first extruder.

Abstract: Methods for operating a medical imaging device for positionally correct representation of non-anatomical structures during an imaging examination may include providing a first 3D image containing at least one anatomical structure, extracting at least one anatomical model from the at least one anatomical structure, providing 2D update images recorded at different times, extracting non-anatomical and anatomical structures from subsets of the update images, calculating a non-anatomical 3D image from at least two partial reconstructions based on the extracted non-anatomical structures, reconstructing an anatomical 3D image based on the extracted anatomical structures, registering the anatomical 3D image with the first 3D image by determining a coordinate transformation, and creating a navigation volume from the anatomical model and the non-anatomical 3D image using the coordinate transformation.

Abstract: The invention relates to a separator drum (10) with a hydraulically actuated, axially movable piston slide valve (20) which can seal off a solids space (14) from at least one solids outlet (18), wherein the piston slide valve (20) can be held in its closed position via a closing chamber (30) that can be filled with closing liquid, in particular closing water, wherein the closing chamber (30) is formed between an underside (21) of the piston slide valve (20) and a top side (35) of a drum lower part (15). According to the invention, the closing chamber (30) has a first closing chamber portion (31) near the rotation axis (R) and a second closing chamber portion (32) remote from the rotation axis (R), wherein the first closing chamber portion (31) is formed by two mutually parallel portions (22, 36) of the underside (21) of the piston slide valve (20) and of the top side (35) of the drum lower part (15), and the second closing chamber portion (32) has at least in part a conical cross section.

Abstract: Medical imaging methods for processing a three-dimensional (3D) image data set with two-dimensional X-ray images from an X-ray machine using a target function. Methods can include providing a 3D image data set of at least one examination zone in which anatomical structures are present, segmenting the image data set to provide a 3D vascular structure model and a 3D bone structure model, recording a first two-dimensional (2D) X-ray image containing at least a portion of the vascular structure and at least a portion of the bone structure, recording a second 2D X-ray image of the examination zone at a different contrast agent concentration, and subtracting the first and second 2D X-ray images to generate a subtraction image. An optimum projective geometry may then be determined using a three-part target function based on the 3D image data and the 2D X-ray images.

Abstract: A method of registering two sets of medical image data taking into account scene changes can include providing a first and a second medical image data set by means of a medical device, subdividing the first and second medical image data sets into an equal number of sub-images, performing a number of individual registrations between the first and second medical image data sets with respective optimization of a similarity measure, identifying the sub-images that have a scene change, and performing a final registration between the first and the second medical image data set by masking out the identified sub-images or a masked out sub-image combination. For each individual registration, at least one sub-image of the first and/or second medical image data set can be masked out by means of a random process when determining the respective measure of similarity.

Abstract: This disclosure relates to an X-ray system for obtaining referencing information in the form of a coordinate transformation between a first volume and a second volume, with the volumes partially overlapping. In this case two partially overlapping subareas of an extended object having a continuous distribution of a physical size are discretely sampled with a measuring apparatus; the volumes are reconstructed and the overlapping volumes are iteratively changed, wherein a bandpass filter is applied to the overlapping volumes, where said bandpass filter changes the Fourier domain representation of the overlapping volumes. The filtered overlapping volumes, in which the artifacts, induced by the discrete sampling, are matched, are compared by means of a measure of similarity, which is iteratively maximized by means of mathematical optimization.

Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet attached to a supporting element, which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets.

Abstract: The invention relates to mixing elements with a reduced structural depth for static mixers, to static mixers comprising at least two mixing elements with a reduced structural depth, and to a method for mixing fluids using a mixing element with a reduced structural depth or a static mixer comprising at least two mixing elements with a reduced structural depth. In the mixing elements, the thickness of the transverse strut at its thickest point is maximally 0.9 to 1.1 times the thickness of the webs multiplied by the cosine of half the opening angle O divided by the sine of the whole opening angle O.