Abstract: A freeze dryer that includes a product chamber configured to accommodate products to be freeze-dried; a condenser connected to the product chamber and configured to trap water during a freeze-drying process; a product chamber cooling circuit configured to cool the product chamber, the product chamber cooling circuit having a first heat transfer fluid; a condenser cooling circuit configured to cool the condenser, the condenser cooling circuit having a second heat transfer fluid and being separate from the product chamber cooling circuit; a first additional cooling circuit having carbon dioxide or ammonia or liquid nitrogen as refrigerant; and a first heat exchanger configured to transfer heat between the condenser cooling circuit and the first additional cooling circuit.

Abstract: A braking system includes: brake circuits independently activated and deactivated and when activated apply braking force at respective wheels; a braking stability module detecting an issue or a failure with a first one of the brake circuits where an unexpected amount of braking torque is being applied as compared to an amount of braking torque applied at a second one of the brake circuits, and mitigating effect of the unexpected amount of braking torque on a yaw rate of the vehicle by i) adjusting the braking torque of the first one of the brake circuits, ii) adjusting braking torque of the second one of the brake circuits, and/or iii) deactivating the first one of the brake circuits and modulating braking torque of the second one of the brake circuits, to compensate for the unexpected amount of braking torque.

Abstract: A hot-formed, chemically prestressable glass article having a low percentage of crystals or crystallites, in particular a plate-shaped, chemically prestressable glass article, as well as to a method and a device for its production are provided. The glass article has a composition including the components SiO2, Al2O3, and Li2O and a content of seed formers (ZrO2, SnO2, and TiO2) of at least 0.8 wt %, as well as at most ten crystals, including crystallites, per kilogram of glass, which have a maximum diameter greater than 1 ?m and up to at most 5 ?m.

Abstract: A medical system (100) provides a setting recommendation (105) for a ventilator. A data interface (110) receives static patient data that includes values of patient parameters that are substantially invariant during a treatment period. A measurement interface (120) receives dynamic patient data that includes values of patient parameters that change during the treatment period. A processing unit (150) determines a new current patient data set based on the currently available patient data immediately after receiving the patient data and initiates, triggered by the determination of the new current patient data set, a comparison between the values of the current patient data set and stored assignment rules from a rule memory. Based on the comparison, a recommended device setting (134) of the ventilator, in view of the current patient data set, is received from a rule memory unit. A recommendation is output based on a comparison with a current device setting.

Abstract: An operating unit (2) sets ventilation parameters of a control unit (11) of a ventilator (1) that includes a gas dispensing device (10) for ventilation gases. The operating unit includes a display unit and an ventilation parameters input element (23, 24). Two or more of the parameters are linked via a relation condition stored in a relation storage module (40). A relation monitor (3) includes a deviation detector (31) detecting a transgression of the relation condition during parameter setting, and outputs warning information via a warning unit (32). This avoids a need for an operator to note the sometimes complicated connections and dependencies expressed in the relations during the parameter setting. The warning may be sent before the new setting value is sent from the operating unit to the control unit. Operating safety is increased and a risk of setting errors is minimized.

Abstract: Torsional vibration damper for a drivetrain of a motor vehicle, having a primary element rotatable around a rotational axis and a secondary element rotatable relative to the primary element against an energy storage. The energy storage includes a helical compression spring unit. The helical compression spring unit is provided in a spring channel, and the helical compression spring unit includes an outer spring. The outer spring is formed as an arc spring and an inner spring is provided inside of the outer spring and virtually coaxial to the outer spring. The inner spring when disassembled from the helical compression spring unit is formed as a straight helical compression spring. The inner spring has a winding direction that is opposed to a winding direction of the outer spring and the inner spring when installed in the torsional vibration damper, is shorter than the outer spring by a value of x.

Abstract: A ventilator (1), for ventilating the lungs of a patient with breathing air, includes a ventilation module (2) for generating a breathing air flow, a determination module (3) for determining a first ventilation parameter as well as a different second ventilation parameter of the ventilator, and a control module (4) for controlling the ventilator as a function of the determined first and/or second ventilation parameter. The control module is configured to reduce the first ventilation parameter automatically over an analysis period including at least one breathing cycle. A classification module (5) is configured to classify a pulmonary status of the lungs of the patient based on a change in the second ventilation parameter, which change was brought about by the automatic reduction of the first ventilation parameter. A process is further provided for ventilating the lungs of a patient with breathing air with a ventilator (1).

Abstract: A medical device is provided with an alarm organization. A process for alarm organization of a medical device is also provided. Based on pressure measured values and flow measured values and with a comparison criterion, it is determined whether an elevation of an airway pressure of an anesthesia device or of a ventilator is caused by a coughing event. A visual and/or acoustic output of a warning or alarm is adapted, indicating the elevated airway pressure PAW_High.

Abstract: The application includes a description of novel intermediates, of new manufacturing steps resulting in a novel and improved process for producing the intermediates and the final compounds, i.e., 6-alkynyl-pyridine derivatives. The intermediates of the invention are useful to produce 6-alkynyl-pyridine derivatives, which compounds are useful for the treatment of cancer.

Abstract: An operating unit (2) sets ventilation parameters of a control unit (11) of a ventilator (1) that includes a gas dispensing device (10) for ventilation gases. The operating unit includes a display unit and an ventilation parameters input element (23, 24). Two or more of the parameters are linked via a relation condition stored in a relation storage module (40). A relation monitor (3) includes a deviation detector (31) detecting a transgression of the relation condition during parameter setting, and outputs warning information via a warning unit (32). This avoids a need for an operator to note the sometimes complicated connections and dependencies expressed in the relations during the parameter setting. The warning may be sent before the new setting value is sent from the operating unit to the control unit. Operating safety is increased and a risk of setting errors is minimized.

Abstract: Systems and methods are described herein. In one embodiment, the method includes receiving a goal associated with a predicate-object pair; receiving utilization data including a plurality of predicate-object pairs including the predicate-object pair associated with the goal; determining a prediction model comprising a plurality of nodes that form a hierarchical structure including a root node and two or more leaf nodes and organized based on one or more of an information gain and a business gain, the two or more leaf nodes including a leaf node associated with the predicate-object pair of the goal; identifying nodes in the hierarchical structure that trace a path from the root node to the node associated with the goal; and causing a recommendation for at least partial completion of the goal to be presented to a user, the recommendation based on the one or more nodes that trace the path.

Abstract: A wind turbine control system comprising a controller of a control mechanism of a wind turbine, wherein the controller implements a computerized real-time blade model to calculate operational parameters of the controller, and wherein the computerized real-time blade model receives as inputs a determined wind turbine operating point and a rotor-plane wind speed value that is estimated in real-time. In another aspect, the embodiments of the invention provide a method of controlling a control mechanism of a wind turbine. Advantageously, the invention provides a more flexible and responsive control system that is able to adapt to changing wind conditions even if those wind conditions are beyond what is usually predicted.

Abstract: A wind turbine control system comprising at least one control module configured to output a control signal for a control mechanism of a wind turbine, and a gain calculator for calculating a gain parameter associated with the control module, wherein the gain parameter is calculated based on a computerized real-time blade model using a determined wind turbine operating point as an input. The blade model may be a blade element momentum model. In another aspect, the invention may be expressed as a method of controlling a control mechanism of a wind turbine.

Abstract: A medical device determines operating situations and a method determines operating situations in a medical device. Based on pressure measured values (99) and flow measured values (97), it is determined whether an elevation of an airway pressure (105) in a medical device is due to a cough event (113) or to a plurality of cough events (117), which indicate an accumulation of secretion. An outputting (41, 42, 44) of a warning (44) or alarm (41, 42) is provided indicating the accumulation of secretion.

Abstract: A ventilator (1) determines states with cough attacks and an operating method for a ventilator determines cough attacks. It is determined on the basis of pressure measured values (13, 21, 19) and flow measured values (11, 15, 17) whether consecutive elevations of an airway pressure in a ventilator (1) are due to one cough event or due to a plurality of cough events. A plurality of cough events indicates a state of a cough attack. An output (41, 42, 44) of a warning (44) or alarm (42) is issued indicating the state.

Abstract: A shoe, comprising a sole and a shoe upper, wherein the sole comprises a sole part which has a base region from which at least one support part extends upwards during the intended use of the shoe, wherein the shoe upper comprises a sock-like section connected to the sole for receiving the foot of the wearer. To obtain improved contact of the shoe with the foot of the wearer, the at least one support part covers the sock-like section on the shoe outer side, wherein no firm connection exists between the support part and the sock-like section over at least a section of the support part and that both the at least one support part and the sock-like section are surrounded by a tensioning element which tensions at least some sections of both the support part and the sock-like section against the foot of the wearer of the shoe.

Abstract: The invention relates to a control apparatus and method for controlling the rotor blades of a wind turbine, and in particular to controlling the rotor blades during an extreme wind event. An extended mode of operation of the wind turbine rotor beyond the cut-out wind speed is provided. In the extended mode of operation, the pitch of the wind turbine blades is actively controlled so that the rotor and the generator idle at a designated rotational speed. The rotational speed may be relatively high, say 15 to 20% of the nominal speed, compared with minimal speeds experienced by purely feathered wind turbine blades, and may be further controlled as a function of the incident wind speed. Output power control in the extended mode may be zero but is preferably a low, but non-zero value. The output power so produced may then be used as an auxiliary power source for controlling the wind turbine in situations where the utility grid fails.

Abstract: The present invention refers to a method for operating a wind turbine, the wind turbine particularly comprising a tower and a rotor with rotor blades. The pitch angles of the rotor blades are adjusted to generate a force on the rotor and the tower. The force is adjusted to counteract and damp an oscillation. The adjustment is enabled by an activation decision unit, if the activation decision unit decides that certain parameters characterising the oscillation or loads of the tower indicate a requirement and/or if the activation decision unit determines that the generated force is sufficient to counteract an oscillation of the tower.

Abstract: The invention presents a method for operating a horizontal axis wind turbine, the wind turbine comprising a tower and a rotor with at least one rotor blade, the rotor being connected to the tower, and being adapted to drive a generator connected to a utility grid, wherein a pitch angle of each rotor blade is adjustable, the method comprising detecting, when the wind turbine is in an idling power producing situation in relation to the utility grid, a tower oscillation, and controlling, when the wind turbine is in the idling power producing situation, the pitch angle of the at least one rotor blade so as to produce aerodynamic forces counteracting the detected tower oscillation.