Patents by Inventor Thomas Kriehuber

Thomas Kriehuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Method For Producing Low Viscous And Highly Concentrated Biopharmaceutical Drug Products In Liquid Formulation
    Publication number: 20230165793
    Abstract: The present invention relates to a method of producing low viscous and highly concentrated biopharmaceutical drug products comprising a biomolecule of interest, the method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, said first phase comprising at least one processing step selected from (a1) harvesting, (a2) purification, (a3) re-buffering, and (a4) enrichment, wherein said at least one processing step in this first phase is carried out in the presence of a composition comprising at least three amino acids, wherein the combination of said at least three amino acids provides at least one positively charged functional group, at least one anti-oxidative functional group, at least one osmolytic function, and at least one buffering function, and (b) a second phase of further processing the drug substance prepared in (a) to obtain a low viscous and highly concentrated biopharmaceutical drug product, said second phase comprising at least one processing step selected fro
    Type: Application
    Filed: November 21, 2022
    Publication date: June 1, 2023
    Applicant: Leukocare AG
    Inventors: Martin Scholz, Kristina Kemter, Jens Altrichter, Thomas Kriehuber
  • Method for producing low viscous and highly concentrated biopharmaceutical drug products in liquid formulation
    Patent number: 11510871
    Abstract: The present invention relates to a method of producing low viscous and highly concentrated biopharmaceutical drug products comprising a biomolecule of interest, the method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, said first phase comprising at least one processing step selected from (a1) harvesting, (a2) purification, (a3) re-buffering, and (a4) enrichment, wherein said at least one processing step in this first phase is carried out in the presence of a composition comprising at least three amino acids, wherein the combination of said at least three amino acids provides at least one positively charged functional group, at least one anti-oxidative functional group, at least one osmolytic function, and at least one buffering function, and (b) a second phase of further processing the drug substance prepared in (a) to obtain a low viscous and highly concentrated biopharmaceutical drug product, said second phase comprising at least one processing step selected fro
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 29, 2022
    Assignee: Leukocare AG
    Inventors: Martin Scholz, Kristina Kemter, Jens Altrichter, Thomas Kriehuber
  • A NOVEL METHOD OF PRODUCING A LIQUID BIOPHARMACEUTICAL DRUG PRODUCT
    Publication number: 20190256551
    Abstract: The present invention relates to a method of producing a liquid biopharmaceutical drug product, comprising a biomolecule of interest, the method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, said first phase comprising at least one processing step selected from (a1) harvesting, (a2) purification, (a3) re-buffering, and (a4) enrichment, wherein said at least one processing step in this first phase is carried out in the presence of a composition comprising at least three amino acids, wherein the combination of said at least three amino acids provides at least one positively charged functional group, at least one anti-oxidative functional group, at least one osmolytic function, and at least one buffering function, and (b) a second phase of further processing the drug substance prepared in (a) to obtain a liquid biopharmaceutical drug product, said second phase comprising at least one processing step selected from (b1) re-buffering, (b2) freezing, (b3) thawing, and (b
    Type: Application
    Filed: September 15, 2017
    Publication date: August 22, 2019
    Applicant: Leukocare AG
    Inventors: Kristina Kemter, Martin Scholz, Jens Altrichter, Thomas Kriehuber
  • A Novel Method for Stabilization of a Biopharmaceutical Drug Product During Processing
    Publication number: 20190216925
    Abstract: The present invention relates to a method of producing a biopharmaceutical drug product comprising a biomolecule of interest, the method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, said first phase comprising at least one processing step selected from (a1) harvesting, (a2) purification, (a3) re-buffering, and (a4) enrichment, wherein said at least one processing step in this first phase is carried out in the presence of a composition comprising at least three amino acids, wherein the combination of said at least three amino acids provides at least one positively charged functional group, at least one anti-oxidative functional group, at least one osmolytic function, and at least one buffering function, and (b) a second phase of further processing the drug substance prepared in (a) to obtain a biopharmaceutical drug product, said second phase comprising at least one processing step selected from (b1) re-buffering, (b2) freezing, (b3) thawing, and (b4) filling; whe
    Type: Application
    Filed: September 15, 2017
    Publication date: July 18, 2019
    Applicant: Leukocare AG
    Inventors: Martin Scholz, Kristina Kemter, Jens Altrichter, Thomas Kriehuber
  • A Novel Method For Producing Low Viscous And Highly Concentrated Biopharmaceutical Drug Products In Liquid Formulation
    Publication number: 20190216734
    Abstract: The present invention relates to a method of producing low viscous and highly concentrated biopharmaceutical drug products comprising a biomolecule of interest, the method comprising: (a) a first phase of preparing a drug substance of the biomolecule of interest, said first phase comprising at least one processing step selected from (a1) harvesting, (a2) purification, (a3) re-buffering, and (a4) enrichment, wherein said at least one processing step in this first phase is carried out in the presence of a composition comprising at least three amino acids, wherein the combination of said at least three amino acids provides at least one positively charged functional group, at least one anti-oxidative functional group, at least one osmolytic function, and at least one buffering function, and (b) a second phase of further processing the drug substance prepared in (a) to obtain a low viscous and highly concentrated biopharmaceutical drug product, said second phase comprising at least one processing step selected fro
    Type: Application
    Filed: September 15, 2017
    Publication date: July 18, 2019
    Applicant: Leukocare AG
    Inventors: Martin Scholz, Kristina Kemter, Jens Altrichter, Thomas Kriehuber