Patents by Inventor Thomas Kronbach

Thomas Kronbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
    Patent number: 7683074
    Abstract: 7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds and methods of treating arthritis and other conditions with the compounds are also provided.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: March 23, 2010
    Assignee: Biotie Therapies GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • 7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
    Patent number: 7419987
    Abstract: 7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds are also provided.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: September 2, 2008
    Assignee: Elbion AG
    Inventors: Norbert Höfgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • 7-Azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
    Publication number: 20080207680
    Abstract: 7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds and methods of treating arthritis and other conditions with the compounds are also provided.
    Type: Application
    Filed: March 10, 2008
    Publication date: August 28, 2008
    Inventors: Norbert Hofgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • 7-azaindoles, use thereof as phosphodiesterase 4 inhibitors and method for producing the same
    Patent number: 7169787
    Abstract: The invention relates to new 7-azaindoles, their use as inhibitors of phosphodiesterase 4 and to methods for their synthesis.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: January 30, 2007
    Assignee: Elbion AG
    Inventors: Norbert Höfgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 7161009
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: January 9, 2007
    Assignee: Elbion AG
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • 7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
    Publication number: 20060258700
    Abstract: 7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds are also provided.
    Type: Application
    Filed: January 10, 2006
    Publication date: November 16, 2006
    Inventors: Norbert Hofgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Publication number: 20040220183
    Abstract: The invention relates to new hydroxyindoles of the Formula, 1
    Type: Application
    Filed: May 27, 2004
    Publication date: November 4, 2004
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Novel 7-azaindoles, use thereof as phosphodiesterase 4 inhibitors and method for producing the same
    Publication number: 20040106641
    Abstract: The invention relates to new 7-azaindoles, their use as inhibitors of phosphodiesterase 4 and to methods for their synthesis.
    Type: Application
    Filed: June 17, 2003
    Publication date: June 3, 2004
    Inventors: Norbert Hofgen, Ute Egerland, Thomas Kronbach, Degenhard Marx, Stefan Szelenyi, Hildegard Kuss, Emmanuel Polymeropoulos
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6613794
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: January 20, 2003
    Date of Patent: September 2, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6602890
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: August 5, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • New hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Publication number: 20030134876
    Abstract: The invention relates to new hydroxyindoles of the Formula, 1
    Type: Application
    Filed: January 20, 2003
    Publication date: July 17, 2003
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6545158
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 8, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6545025
    Abstract: The invention relates to nets hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 8, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Process for the treatment of erectile dysfunction and product therefor
    Patent number: 6465465
    Abstract: The invention relates to the use of pyrido[3,2-e]-pyrazinones of formula 1 as inhibitors of phosphodiesterase 5 for the treatment of erectile dysfunction (impotence).
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: October 15, 2002
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Degenhard Marx, Norbert Höfgen, Ute Egerland, Stefan Szelényi, Thomas Kronbach
  • PROCESS FOR THE TREATMENT OF ERECTILE DYSFUNCTION AND PRODUCT THEREFOR
    Publication number: 20020147199
    Abstract: The invention relates to the use of pyrido[3,2-e]-pyrazinones of formula 1 as inhibitors of phosphodiesterase 5 for the treatment of erectile dysfunction (impotence).
    Type: Application
    Filed: February 8, 2001
    Publication date: October 10, 2002
    Inventors: Degenhard Marx, Norbert Hofgen, Ute Egerland, Stefan Szelenyi, Thomas Kronbach
  • New hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Publication number: 20020137745
    Abstract: The invention relates to new hydroxyindoles of the Formula, 1
    Type: Application
    Filed: February 21, 2002
    Publication date: September 26, 2002
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Publication number: 20020119971
    Abstract: The invention relates to new hydroxyindoles of the Formula, 1
    Type: Application
    Filed: February 21, 2002
    Publication date: August 29, 2002
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Use of maduraohtalazine derivatives as inhibitors of proinflammatory cytokines
    Patent number: 6440968
    Abstract: The maduraphthalazine derivatives of the formula (4) are able to inhibit the effect of the cytokines interleukin-2, interleukin-4 and interleukin-5 and are suitable for the production of pharmaceuticals.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: August 27, 2002
    Assignee: Elbion G.m.b.H.
    Inventors: Regina Draheim, Thomas Kronbach, Lothar Heinisch, Ernst Roemer, Norbert Höfgen, Hildegard Poppe, Peter Jütten, Wolfgang Haas, Walter Werner, Udo Gräfe
  • New hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Publication number: 20020115651
    Abstract: The invention relates to new hydroxyindoles of the Formula, 1
    Type: Application
    Filed: February 21, 2002
    Publication date: August 22, 2002
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation
    Patent number: RE38624
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: October 12, 2004
    Assignee: Elbion AG
    Inventors: Norbert Hofgen, Ute Egerland, Hildegard Kuss, Degenhard Marx, Stefan Szelenyi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer