Patents by Inventor Thomas Kruse

Thomas Kruse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11565712
    Abstract: Systems and methods for managing speed thresholds for a fleet of vehicles are disclosed. Input is used to provide associations between particular weather-relation conditions (such as rain) and arithmetic operations, that may be used to determine a current speed threshold as a function of a local posted speed limit at the current location of a vehicle. The current speed threshold is subsequently used to detect whether vehicles are exceeding the current speed threshold.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: January 31, 2023
    Assignee: SmartDrive Systems, Inc.
    Inventors: Samuel Thomas Kruse, David Wagstaff, Jason Palmer
  • Patent number: 11555498
    Abstract: A magnetic coupling assembly includes a rotatable male coupling member, a rotatable female coupling member, a static separation member, a first channel, a second channel, a third channel, and a magnetic coupling section of the static separation member, wherein the magnetic coupling section is a section of the static separation member. The rotatable female coupling member and the rotatable male coupling member are rotatably coupled by magnets through the magnetic coupling section. The first channel, the second channel, and the third channel contain fluid forced to flow through the first, second, and third channels for cooling and rotodynamic stabilization.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: January 17, 2023
    Assignee: FSubsea AS
    Inventors: Alexander Fuglesang, Tommy Westberg, Thomas Navjord, Marius Kruse Aas
  • Patent number: 11541122
    Abstract: The present invention provides glucose sensitive insulin derivatives comprising a macrocycle, a glucose mimetic and human insulin or an analogue thereof, and their pharmaceutical use. Furthermore, the invention relates to pharmaceutical compositions comprising such glucose sensitive insulin derivatives, and to the use of such compounds for the treatment or prevention of medical conditions relating to diabetes.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: January 3, 2023
    Inventors: Thomas Hoeg-Jensen, Alice Ravn Madsen, Thomas Kruse, Per Sauerberg, Anthony Murray, Andrew Michael Chapman, Anthony Peter Davis
  • Patent number: 11457698
    Abstract: A lace tensioning device includes a housing component having an interior region, a first aperture, and a second aperture, and a spool component that is rotatably positionable within the interior region of the housing component. The spool component has a central cylindrical member and a lumen that extends through the central cylindrical portion. The spool component is rotatable within the interior region of the housing component to align one end of the lumen with the first aperture and to align an opposite end of the lumen with the second aperture to enable a lace to be inserted through the first aperture, the lumen, and the second aperture so that opposing ends of the lace are positioned exterior to the housing component. A knot may then be tied in the lace and the lace retracted to couple the lace with the housing component and spool component.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: October 4, 2022
    Assignee: Boa Technology, Inc.
    Inventors: Robert E. Burns, Randon Kruse, Thomas Pollack
  • Publication number: 20220310350
    Abstract: Systems and methods are provided for improving thermal management strategies of a cathode assembly of an X-ray tube. In one embodiment, an X-ray tube comprises an anode assembly and a cathode assembly, wherein the cathode assembly includes one or more elements that include an internal porous section for controlling a flow of heat within the cathode assembly during operation of the X-ray tube. In this way, heat conduction to temperature sensitive aspects of the cathode assembly may be reduced, while enabling sufficient heat transfer to other parts of the cathode assembly to minimize deformation.
    Type: Application
    Filed: June 14, 2022
    Publication date: September 29, 2022
    Inventors: Kevin Kruse, Thomas Murray
  • Publication number: 20220266552
    Abstract: The invention relates to a method for repairing a damaged point of a fiber composite component which is formed from at least one fiber ply of a fiber material of a fiber composite substance and a matrix material of the fiber composite substance, in which matrix material the fiber material is embedded, wherein the method comprises the following steps: removing the damaged point from the fiber composite component and producing a repair cavity in the fiber composite component, introducing at least one reparative fiber ply of a fiber material into the repair cavity produced in the fiber composite component, and curing the matrix material, in which the fiber material of the reparative fiber ply is embedded, after introducing the reparative fiber ply into the repair cavity of the fiber composite component, wherein at least one reparative fiber ply having a ply thickness that is smaller than the ply thickness of the fiber plies of the rest of the fiber composite component is introduced into the repair cavity.
    Type: Application
    Filed: August 6, 2020
    Publication date: August 25, 2022
    Inventors: Dirk Holzhüter, Jens KOSMANN, Thomas Körwien, Anton Maier, Thomas Kruse-Strack
  • Patent number: 11419389
    Abstract: A reel based closure device includes a housing, a tension member, a spool that is rotatably positioned within the housing, and a tightening component that is positioned axially above the spool and that is operably coupled therewith so that an operation of the tightening component causes the spool to rotate within the housing to wind the tension member about the spool. The reel based closure device also includes a coupling component that is separate from the tension member and that frictionally engages with a distal end of the tension member so that the coupling component is removably fixed to the tension member. The spool component includes a coupling feature within which the coupling component is positioned to attach the tension member to the spool.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: August 23, 2022
    Assignee: Boa Technology Inc.
    Inventors: Thomas Pollack, Eric Whewell, Randon Kruse, Mark Clementi, Josef Duller, Brendan Hoskens, David Roland, Mark Soderberg
  • Publication number: 20220233773
    Abstract: Disclosed herein are systems and methods for automated insulin delivery that reduce a risk of hypoglycemia from automatically delivering correction boluses. Rather than automatically delivering a correction bolus when a current or future predicted glucose level of a user is over a high glucose threshold, the system can review additional factors to determine whether an automatic correction bolus is appropriate. For example, the system can be prevented from delivering an automatic correction bolus if the user's glucose levels are falling at greater than a predetermined rate and/or if a current glucose level is greater than a future predicted glucose level even if the user's current or predicted future glucose levels is over the high threshold.
    Type: Application
    Filed: January 28, 2022
    Publication date: July 28, 2022
    Inventors: Jose Ricardo Rueda, Paul Harris, Thomas R. Ulrich, Geoffrey A. Kruse
  • Patent number: 11380509
    Abstract: Systems and methods are provided for improving thermal management strategies of a cathode assembly of an x-ray tube. In one embodiment, an x-ray tube comprises an anode assembly and a cathode assembly, wherein the cathode assembly includes one or more elements that include an internal porous section for controlling a flow of heat within the cathode assembly during operation of the x-ray tube. In this way, heat conduction to temperature sensitive aspects of the cathode assembly may be reduced, while enabling sufficient heat transfer to other parts of the cathode assembly to minimize deformation.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: July 5, 2022
    Assignee: GE Precision Healthcare LLC
    Inventors: Kevin Kruse, Thomas Murray
  • Publication number: 20220184184
    Abstract: The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 16, 2022
    Inventors: Thomas Hoeg-Jensen, Carsten Behrens, Emiliano Clo, Martin Werner Borchsenius Muenzel, Per Sauerberg, Thomas Kruse, Jane Spetzler, Ulrich Sensfuss, Claudia Ulrich Hjoerringgaard, Henning Thoegersen, Vojtech Balsanek, Zuzana Drobnakova, Ladislav Droz, Miroslav Havranek, Vladislav Kotek, Milan Stengl, Ivan Snajdr, Hana Drusanova
  • Patent number: 11353314
    Abstract: A method for determining a distance between components has the steps of providing a first conductive section in or on the first component in a region directed toward the second component, providing a second conductive section in or on the second component in a region directed toward the first conductive section, feeding a first voltage pulse into a first connection of the first conductive section, capturing a reflection voltage pulse in response to the first voltage pulse at the first connection, determining an impedance profile along the first conductive section by evaluating the reflection voltage pulse, and determining a distance between the components along the first conductive section by calculating a corresponding local distance, associated with the determined impedance profile, between the first conductive section and the second conductive section.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: June 7, 2022
    Assignees: Airbus Defence and Space GmbH, Airbus Operations GmbH
    Inventors: Christopher Buchmann, Alois Friedberger, Thomas Kruse, Thomas Körwien
  • Publication number: 20220081451
    Abstract: This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.
    Type: Application
    Filed: October 13, 2021
    Publication date: March 17, 2022
    Inventors: Thomas Kruse, Mikael Kofod-Hansen, Martin Werner Borchsenius Muenzel, Henning Thoegersen, Per Sauerberg, Jakob Ewald Rasmussen, Carsten Behrens, Thomas Hoeg-Jensen, Vojtech Balsanek, Zuzana Drobnakova, Ladislav Droz, Miroslav Havranek, Vladislav Kotek, Milan Stengl, Ivan Snajdr, Hana Drusanova
  • Publication number: 20220047708
    Abstract: The present invention provides glucose sensitive insulin derivatives comprising a macrocycle, a glucose mimetic and human insulin or an analogue thereof, and their pharmaceutical use. Furthermore, the invention relates to pharmaceutical compositions comprising such glucose sensitive insulin derivatives, and to the use of such compounds for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: September 18, 2019
    Publication date: February 17, 2022
    Inventors: Thomas Hoeg-Jensen, Alice Ravn Madsen, Thomas Kruse, Per Sauerberg, Anthony Murray, Andrew Michael Chapman, Anthony Peter Davis
  • Publication number: 20220033106
    Abstract: An indication device for monitoring the structural integrity of a repair location on a laminate structure, produced from a composite material, of a part of an aircraft outer skin is specified. The indication device has at least one elongate, thin indicator strip. The indicator strip is detachably applied to the outer layer of the laminate structure in the immediate vicinity of the repair location. The indicator strip is designed to indicate a predefined residual strength of an adhesive joint of a repair patch to the surrounding composite material.
    Type: Application
    Filed: November 25, 2019
    Publication date: February 3, 2022
    Applicant: Airbus Defence and Space GmbH
    Inventors: Thomas Körwien, Anton Maier, Thomas Kruse, Jens Holtmannspötter
  • Patent number: 11201893
    Abstract: A system for assessing potential cybersecurity threats to a subject system is provided. The system includes a computer system including at least one processor in communication with at least one memory device. The at least one processor is programmed to: receive a subject system to analyze, determine a potential hazard event associated with the subject system, generate an attack graph associated with the potential hazard event, wherein the attack graph includes a plurality of actions, determine an exploitability score for each of the plurality of actions, determine an uncertainty level for each of the plurality of actions based on the corresponding exploitability score, aggregate the plurality of actions including the corresponding exploitability scores and the corresponding uncertainty levels to determine one or more vulnerabilities of the subject system, and generate a response to the one or more vulnerabilities of the subject system.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: December 14, 2021
    Assignee: THE BOEING COMPANY
    Inventors: David Thomas Kruse, Benjamin Joseph Steffes, Nathan Mackey, Moon Kim
  • Patent number: 11186595
    Abstract: This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates. The diboron compounds are characterized by formula (I), which is: R1-X—R2, and wherein “X” is a mono- to multiatomic linker and where R1 and R2, which may be identical or different, each represents a group of Formula (11a) or (IIb) Also described are diboron conjugates represented by the general Formula (I?), which is: R1?-X?—R2?, in which either the moeities R1? or R2? or X? carry a drug that is covalently attached to the diboron compound.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: November 30, 2021
    Assignee: Novo Nordisk A/S
    Inventors: Thomas Kruse, Mikael Kofod-Hansen, Martin Werner Borchsenius Muenzel, Henning Thoegersen, Per Sauerberg, Jakob Ewald Rasmussen, Carsten Behrens, Thomas Hoeg-Jensen, Vojtech Balsanek, Zuzana Drobnakova, Ladislav Droz, Miroslav Havranek, Vladislav Kotek, Milan Stengl, Ivan Snajdr, Hana Drusanova
  • Patent number: 11117947
    Abstract: The invention relates to a derivative of a GLP-1 analogue, which analogue comprises a first K residue at a position corresponding to position 27 of GLP-1(7-37) (SEQ ID NO: 1); a second K residue at a position corresponding to position T of GLP-1(7-37), where T is an integer in the range of 7-37 except 18 and 27; and a maximum of ten amino acid changes as compared to GLP-1(7-37); wherein the first K residue is designated K27, and the second K residue is designated KT; which derivative comprises two albumin binding moieties attached to K27 and KT, respectively, via a linker, wherein the albumin binding moiety comprises a protracting moiety selected from HOOC—(CH2)x—CO— and HOOC—C6H4—O—(CH2)y—CO—; in which x is an integer in the range of 6-16, and y is an integer in the range of 3-17; wherein the linker comprises an element of the formula —NH—(CH2)2—(O—(CH2)2)k—O—(CH2)n—CO—, wherein k is an integer in the range of 1-5, and n is an integer in the range of 1-5; or a pharmaceutically acceptable salt, amide, or este
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: September 14, 2021
    Assignee: Novo Nordisk A/S
    Inventors: Birgit Wieczorek, Jane Spetzler, Thomas Kruse, Lars Linderoth, Jacob Kofoed
  • Publication number: 20210261150
    Abstract: Systems and methods for managing speed thresholds for a fleet of vehicles are disclosed. Input is used to provide associations between particular weather-relation conditions (such as rain) and arithmetic operations, that may be used to determine a current speed threshold as a function of a local posted speed limit at the current location of a vehicle. The current speed threshold is subsequently used to detect whether vehicles are exceeding the current speed threshold.
    Type: Application
    Filed: April 20, 2021
    Publication date: August 26, 2021
    Inventors: Samuel Thomas Kruse, David Wagstaff, Jason Palmer
  • Publication number: 20210263184
    Abstract: Systems and methods for detecting a sitting duck scenario of a vehicle on or near a road are disclosed. The current location and speed of the vehicle are used for different comparisons and/or determinations, including a comparison to road-specific information to determine whether the vehicle is in a particular proximity of a highway, and a determination whether the vehicle has been stationary continuously for at least a specified duration. Additional comparisons and/or determinations may be used. If such an occurrence has been detected, one or more notifications are generated, and provided to one or more of the vehicle operator and/or a remote computing server.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 26, 2021
    Inventors: David Wagstaff, Samuel Thomas Kruse, Jason Palmer
  • Patent number: 11034746
    Abstract: The invention relates to a derivative of a GLP-1 analogue, which analogue comprises a first K residue at a position corresponding to position 27 of GLP-1(7-37) (SEQ ID NO: 1); a second K residue at a position corresponding to position T of GLP-1(7-37), where T is an integer in the range of 7-37 except 18 and 27; and a maximum of ten amino acid changes as compared to GLP-1(7-37); wherein the first K residue is designated K27, and the second K residue is designated KT; which derivative comprises two albumin binding moieties attached to K27 and KT, respectively, via a linker, wherein the albumin binding moiety comprises a protracting moiety selected from HOOC—(CH2)2—CO— and HOOC—C6H4—O—(CH2)y—CO—; in which x is an integer in the range of 6-16, and y is an integer in the range of 3-17; wherein the linker comprises an element of the formula —NH—(CH2)2—(O—(CH2)2)k—O—(CH2)n—CO—, wherein k is an integer in the range of 1-5, and n is an integer in the range of 1-5; or a pharmaceutically acceptable salt, amide, or este
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: June 15, 2021
    Assignee: Novo Nordisk A/S
    Inventors: Birgit Wieczorek, Jane Spetzler, Thomas Kruse, Lars Linderoth, Jacob Kofoed