Patents by Inventor Thomas L. Pisani

Thomas L. Pisani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION OF GLOBOTRIAOSYLCERAMIDE (GLC) IN HUMAN URINE SAMPLES USING AN ANTIBODY SANDWICH
    Publication number: 20120178105
    Abstract: Applicant has developed an assay for the detection of GL3 in human samples using a sandwich based immunoassay in which utilizes a pair of GL3 specific monoclonal antibodies, one for capture and one for detection, to create an antibody “sandwich” around the GL3 ligand. To further increase sensitivity, Applicant has modified traditional sandwich based assays by complexing the capture antibody with GL3 before adding the sample or detector antibody, providing an inhibition based assay.
    Type: Application
    Filed: January 10, 2011
    Publication date: July 12, 2012
    Applicant: Genzyme Corporation
    Inventors: PAUL F. HALLORAN, Michael A. Holland, Thomas Liponis, Thomas L. Pisani
  • INDIRECT LATERAL FLOW SANDWICH ASSAY
    Publication number: 20120107956
    Abstract: Disclosed herein are indirect lateral flow sandwich assays, in which the target analyte binds an analyte-specific reagent comprising a first member of a conjugate pair, forming a complex which contacts and binds a colored particulate label comprising a complementary member of said conjugate pair, forming a second complex. Capture of this analyte-comprising, second complex by an immobilized analyte specific capture reagent results in the formation of an immobilized labeled sandwich complex that can be detected.
    Type: Application
    Filed: September 12, 2011
    Publication date: May 3, 2012
    Inventors: HANS BOEHRINGER, Mark Daquipa, Fon-Chiu Mia Chen, Hsin Ming Yang, Thomas L. Pisani, Sumitra Nag, Jay Salhaney, Marcella B. Holdridge, Erika Johnston, Jeremy Schonhorn
  • Indirect lateral flow sandwich assay
    Publication number: 20080138842
    Abstract: Disclosed herein are indirect lateral flow sandwich assays, in which the target analyte binds an analyte-specific reagent comprising a first member of a conjugate pair, forming a complex which contacts and binds a colored particulate label comprising a complementary member of said conjugate pair, forming a second complex. Capture of this analyte-comprising, second complex by an immobilized analyte specific capture reagent results in the formation of an immobilized labeled sandwich complex that can be detected.
    Type: Application
    Filed: November 9, 2007
    Publication date: June 12, 2008
    Inventors: Hans Boehringer, Mark Daquipa, Fon-Chiu Mia Chen, Hsin Ming Yang, Thomas L. Pisani, Sumitra Nag, Jay Salhaney, Marcella B. Holdrige, Erika Johnston, Jeremy Schonhorn