Patents by Inventor Thomas L. Reiland

Thomas L. Reiland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Compositions Comprising Effervescent Agents and Fenofibrate
    Publication number: 20100021393
    Abstract: A pharmaceutical composition comprising at least one effervescent agent and a fibrate and a process for making such composition. The fibrate is fenofibrate and the effervescent agent are in a dosage form. The dosage form increases dissolution and absorption of fenofibrate in biological conditions where the form contacts acidic gastric fluid after oral administration.
    Type: Application
    Filed: October 5, 2009
    Publication date: January 28, 2010
    Applicant: Abbott Laboratories
    Inventors: Yisheng Chen, Yihong Qiu, Thomas L. Reiland
  • Methods and compositions for pulmonary administration of a TNFa inhibitor
    Publication number: 20090110679
    Abstract: The invention describes methods of pulmonary delivery of a TNF? inhibitor to a subject having a disorder in which TNF? is detrimental, such that the disorder is treated. Also included is a method of achieving systemic circulation of a TNF? inhibitor in a subject comprising administering the TNF? inhibitor to the central lung region or the peripheral lung region of the subject via inhalation, such that systemic circulation of the TNF? inhibitor is achieved.
    Type: Application
    Filed: July 10, 2008
    Publication date: April 30, 2009
    Inventors: Luk-Chiu Li, Yi Shi, Thomas L. Reiland, Masahiro Sakagami, Katherine Nicholson, Peter R. Byron
  • Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
    Patent number: 6383517
    Abstract: A process for preparing a solid formulation of a lipid-regulating agent comprising dissolving said lipid-regulating agent particles in a surfactant solution, premixing an excipient, wet granulating the mixture, drying the mixture and forming a finished dosage form.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: May 7, 2002
    Assignee: Abbott Laboratories
    Inventors: Yihong Qiu, Venkatramana M. Rao, Kevin R. Engh, Thomas L. Reiland
  • Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
    Patent number: 6368622
    Abstract: A process for preparing a solid formulation of a lipid-regulating agent comprising forming a mixture of said lipid-regulating agent with a surfactant; granulating said mixture by melting, mixing, and congealing said mixture; and optionally forming a finished dosage form.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: April 9, 2002
    Assignee: Abbott Laboratories
    Inventors: Yisheng Chen, Kevin R. Engh, Yihong Qiu, Thomas L. Reiland
  • Method for treating sexual dysfunction with apomorphine at specified plasma concentration levels
    Publication number: 20020006933
    Abstract: Methods for administering apomorphine to a patient for the treatment of sexual dysfunctions while reducing undesirable side effects are disclosed. In the methods, the concentration of apomorphine is attained within the patients' plasma of up to 10 nanograms per milliliter. Advantageously, this concentration may be achieved with less than 15% of patients so treated experiencing emesis. Methods of administration are intranasally, by inhalation to the lungs or by oral ingestion.
    Type: Application
    Filed: March 14, 2001
    Publication date: January 17, 2002
    Applicant: TAP Holdings, Inc.
    Inventors: Pramod K. Gupta, John Daniel Bollinger, Yisheng Chen, Jack Yuqun Zheng, Thomas L. Reiland, Dennis Y. Lee
  • PROCESS FOR PREPARING SOLID FORMULATIONS OF LIPIDREGULATING AGENTS WITH ENHANCED DISSOLUTION AND ABSORPTION
    Publication number: 20010006655
    Abstract: A process for preparing a solid formulation of a lipid-regulating agent comprising forming a mixture of said lipid-regulating agent with a surfactant; granulating said mixture by melting, mixing, and congealing said mixture; and optionally forming a finished dosage form.
    Type: Application
    Filed: January 29, 1999
    Publication date: July 5, 2001
    Inventors: YISHENG CHEN, KEVIN R. ENGH, YIHOUNG QIU, THOMAS L. REILAND
  • Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
    Patent number: 6180138
    Abstract: A process for the preparation of solid formulations of a lipid-regulating agent having enhanced dissolution and absorption characteristics, in which a micronized mixture of the said lipid-regulating agent, and optionally one or more excipients, is suspended in a surfactant solution, dried and optionally granulated, and optionally converted to a finished dosage form.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: January 30, 2001
    Assignee: Abbott Laboratories
    Inventors: Kevin R. Engh, Yihong Qiu, Thomas L. Reiland
  • Compositions and method for the sublingual or buccal administration therapeutic agents
    Patent number: 5487898
    Abstract: Pharmaceutical compositions for the sublingual or buccal administration of therapeutic agents which are normally degraded upon oral administration comprise such a therapeutic agent, a solvent, optionally a cosolvent and/or hydrogel, and an oral mucosal membrane transport enhancing agent which is selected from the group consisting of essential and volatile oils and inorganic and organic acids.
    Type: Grant
    Filed: February 7, 1994
    Date of Patent: January 30, 1996
    Assignee: Abbott Laboratories
    Inventors: Mou-Ying F. Lu, Thomas L. Reiland
  • Compositions and methods for the sublingual or buccal administration of therapeutic agents
    Patent number: 5284657
    Abstract: Pharmaceutical compositions for the sublingual or buccal administration of therapeutic agents (particularly polypeptides) which are normally degraded upon oral administration comprise such a therapeutic agent, a solvent, optionally a cosolvent and/or hydrogel, and an oral mucosal membrane transport enhancing agent which is selected from the group consisting of essential and volatile oils and inorganic and organic acids.
    Type: Grant
    Filed: November 30, 1992
    Date of Patent: February 8, 1994
    Assignee: Abbott Laboratories
    Inventors: Mou-Ying F. Lu, Thomas L. Reiland
  • Pharmaceutical granules and tablets made therefrom
    Patent number: 5009897
    Abstract: A pharmaceutical granule comprising a core of active pharmaceutical agent and a coating of a polymer/microcrystalline cellulose is provided. These granules permit superior tableting of pharmaceutical agents whose physical properties in granule form render them unsuitable for conventional tableting.
    Type: Grant
    Filed: July 12, 1990
    Date of Patent: April 23, 1991
    Assignee: Abbott Laboratories
    Inventors: Dale R. Brinker, Thomas L. Reiland