Patents by Inventor Thomas Leto

Thomas Leto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calmodulin binding peptide derivatives of non-erythroid alpha spectrin
    Patent number: 5182262
    Abstract: The present invention relates to a polypeptide and derivatives thereof deduced from the native structure of non-erythroid alpha spectrin and compositions thereof. One embodiment of the invention is 24 amino acids in length and composed of the following linear sequence of residues: Lys-Thr-Ala-Ser-Pro-Trp-Lys-Ser-Ala-Arg-Leu- Met-Val-His-Thr-Val-Ala-Thr-Phe-Asn-Ser-Ile-Lys-Glu. The invention further relates to methods of using the polypeptide, such as methods for treating disorders including prophylaxis against organ and tissue transplant rejection or treatment of autoimmune disorders.
    Type: Grant
    Filed: March 2, 1989
    Date of Patent: January 26, 1993
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventor: Thomas Leto