Patents by Inventor Thomas Lewis

Thomas Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6712010
    Abstract: The present disclosure defines a metal worktable comprising a tabletop and a plurality of table legs. The worktable has leg-supporting gussets to secure each of the table legs. Each gusset has a socket for receiving one of the table legs. Inside the socket of the gusset, there are stop protrusions that prevent the top surface of the table leg from directly contacting the underside of the tabletop. The worktable also has a inverted hat-shaped channel frame having a pair of side flanges that form the “brim” of the inverted hat shape. There are openings in the channel frame corresponding to the location of the table legs. At each opening in the channel frame, the corresponding leg-supporting gusset is recessed in the channel frame. The gusset contacts the side flanges of the channel frame rather than the underside of the tabletop. The channel frame is attached to the underside of the tabletop. Additionally, the corners of the tabletop are mitered to form a continuous lip.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: March 30, 2004
    Assignee: Metal Masters Foodservice Equipment Co., Inc.
    Inventors: William L. Bartz, Jr., Thomas A. Lewis
  • Publication number: 20040035337
    Abstract: The present invention is a metal worktable comprising a tabletop and a plurality of table legs. The worktable has leg-supporting gussets to secure each of the table legs. Each gusset has a socket for receiving one of the table legs. Inside the socket of the gusset, there are stop protrusions that prevent the top surface of the table leg from directly contacting the underside of the tabletop. The worktable also has a inverted hat-shaped channel frame having a pair of side flanges that form the “brim” of the inverted hat shape. There are openings in the channel frame corresponding to the location of the table legs. At each opening in the channel frame, the corresponding leg-supporting gusset is recessed in the channel frame. The gusset contacts the side flanges of the channel frame rather than the underside of the tabletop. The channel frame is attached to the underside of the tabletop.
    Type: Application
    Filed: August 21, 2002
    Publication date: February 26, 2004
    Inventors: William L. Bartz, Thomas A. Lewis
  • Publication number: 20040023964
    Abstract: A class of 7-phenylimidazo[1,2-b][1,2,4]triazine derivatives, substituted at the meta position of the phenyl ring by an optionally substituted aryl or heteroaryl group which is directly attached or bridged by an oxygen atom or a —NH— linkage, being selective ligands for GABAA receptors, in particular having good affinity for the &agr;2 and/or &agr;3 and/or &agr;5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
    Type: Application
    Filed: May 8, 2003
    Publication date: February 5, 2004
    Inventors: Michela Bettati, Peter Blurton, William Robert Carling, Mark Stuart Chambers, David James Hallett, Andrew Jennings, Richard Thomas Lewis, Michael Geoffrey Neil Russell, Leslie Joseph Street, Helen Jane Szekeres, Monique Bodil Van Neil
  • Patent number: 6642229
    Abstract: A class of 3-phenylimidazo(1,2-a)pyrimidine derivatives (of Formula I, or salt or prodrug thereof: I) wherein Y represents a chemical bond, an oxygen atom, or a —NH— linkage; Z represents an optionally substituted aryl or heteroaryl group; R1 represents hydrogen, hydrocarbon, a heterocyclic group, halogen, cyano trifluoromethyl, nitro, —ORa, —SRa, —SORa, —SO2Ra, —SO2NRaRb, —NRaRb, —NRaCORb, —NRaCO2Rb, —CORa, CO2Ra, —CONRaRb or —CRa═NORb; and Ra and Rb independently represent hydrogen, hydrocarbon or a heterocyclic group.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: November 4, 2003
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Wesley Peter Blackaby, Simon Charles Goodacre, David James Hallett, Andrew Jennings, Richard Thomas Lewis, Kevin William Moore, Leslie Joseph Street
  • Publication number: 20030176449
    Abstract: A class of 3-phenylimidazo(1,2-&agr;) pyrimidine derivatives (of Formula I, or salt or prodrug thereof: I) wherein Y represents a chemical bond, an oxygen atom, or a —NH— linkage; Z represents an optionally substituted aryl or heteroaryl group; R1 represents hydrogen, hydrocarbon, a heterocyclic group, halogen, cyano trifluoromethyl, nitro, —ORa, —SRa, —SORa, —SO2Ra, —SO2NRaRb, —NRaRb, —NRaCORb, —NRaCO2Rb, —CORa, CO2Ra, —CONRaRb or —CRa═NORb; and Ra and Rb independently represent hydrogen, hydrocarbon or a heterocyclic group.
    Type: Application
    Filed: November 22, 2002
    Publication date: September 18, 2003
    Inventors: Wesley Peter Blackaby, Simon Charles Goodacre, David James Hallett, Andrew Jennings, Richard Thomas Lewis, Kevin William Moore, Leslie Joseph Street
  • Publication number: 20030158203
    Abstract: A class of substituted 1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a difluoro- or trifluoro-substituted phenyl ring at the 3-position, a triazolyl-methoxy moiety at the 6-position, and a tert-butyl group at the 7-position, are selective ligands for GABAA receptors, in particular having high affinity for &agr;2 and/or &agr;3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 21, 2003
    Applicant: Merck & Co., Inc.
    Inventors: William Robert Carling, Jose Luis Castro Pineiro, Richard Thomas Lewis, Kevin William Moore, Leslie Joseph Street
  • Publication number: 20030135032
    Abstract: The present invention provides isolated nucleic acid molecules that encode one or more of the enzymes required to produce PDTC. The present invention also provides isolated proteins encoded by nucleic acid molecules of the invention. In another aspect, the present invention provides methods for reducing the amount of a metal in a substrate, such as soil. In yet another aspect, the present invention provides methods for reducing the amount of carbon tetrachloride in a substrate, such as soil.
    Type: Application
    Filed: October 1, 2002
    Publication date: July 17, 2003
    Inventors: Thomas A. Lewis, Andrzej Paszczynski, Ronald L. Crawford, Jonathan L. Sebat, Marc S. Cortese
  • Publication number: 20030013716
    Abstract: A class of pyrazino[2,3-d]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 5-position, a substituted alkoxy moiety at the 3-position, and a range of substituents at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 and/or &agr;5 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, ceonvulsions and cognitive disorders.
    Type: Application
    Filed: June 18, 2002
    Publication date: January 16, 2003
    Inventors: Wesley Peter Blackaby, Richard Thomas Lewis, Leslie Joseph Street
  • Patent number: 6500828
    Abstract: 1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a difluoro-or tri-fluoro-substituted phenyl ring at the 3-position, a triazolyl moiety at the 6-position, and a tert-butyl group at the 7-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are useful in the treatment of anxiety and convulsions.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: December 31, 2002
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: William Robert Carling, Jose Luis Castro Pineiro, Richard Thomas Lewis, Kevin William Moore, Leslie Joseph Street
  • Publication number: 20020193385
    Abstract: A class of 3-phenylimidazo[1,2-&agr;]pyrimidine derivatives, substituted at the meta position of the phenyl ring by an optionally substituted aryl or heteroaryl group which is directly attached or bridged by an oxygen atom or a —NH— linkage, and further substituted on the phenyl ring by alkyl, trifluoromethyl, alkoxy or one or two halogen atoms, especially fluoro, are selective ligands for GABAA receptors, in particular having good affinity for the &agr;2 and/or &agr;3 and/or &agr;5 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
    Type: Application
    Filed: March 19, 2002
    Publication date: December 19, 2002
    Inventors: Mark Stuart Chambers, Simon Charles Goodacre, David James Hallett, Andrew Jennings, Philip Jones, Richard Thomas Lewis, Kevin William Moore, Michael Geoffrey Neil Russell, Leslie Joseph Street, Helen Jane Szekeres
  • Patent number: 6440563
    Abstract: A process for preparing pins for connecting carbon electrodes is presented. In particular, a process for preparing pins for connecting carbon electrodes including the steps of combining calcined coke, a liquid pitch binder and carbon fibers derived from mesophase pitch to form a pinstock blend; extruding the pinstock blend to form a green pinstock; baking the green pinstock to form a carbonized pinstock; and graphitizing the carbonized pinstock by maintaining the carbonized pinstock at a temperature of at least about 2500° C. for no more than about 18 hours is presented. The pins prepared by the inventive process are also presented.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: August 27, 2002
    Assignee: UCAR Carbon Company Inc.
    Inventors: Richard Liichang Shao, James William Kortovich, Irwin Charles Lewis, Richard Thomas Lewis
  • Patent number: 6333336
    Abstract: Pyrazolo[4,3-c]pyridin-3-one derivatives substituted at the 2-position by an optionally substituted aryl or heteroaryl moiety, and having pendant substituents at the 7-position and optionally also at the 6-position, are selective ligands for GABAA receptors, particularly having high affinity for the &agr;2 and/or &agr;3 subunit, and are useful in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: December 25, 2001
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Wesley Peter Blackaby, Jose Luis Castro Pineiro, Richard Thomas Lewis, Michael Geoffrey Neil Russell, Leslie Joseph Street
  • Publication number: 20010033036
    Abstract: A process for preparing pins for connecting carbon electrodes is presented. In particular, a process for preparing pins for connecting carbon electrodes including the steps of combining calcined coke, a liquid pitch binder and carbon fibers derived from mesophase pitch to form a pinstock blend; extruding the pinstock blend to form a green pinstock; baking the green pinstock to form a carbonized pinstock; and graphitizing the carbonized pinstock by maintaining the carbonized pinstock at a temperature of at least about 2500° C. for no more than about 18 hours is presented. The pins prepared by the inventive process are also presented.
    Type: Application
    Filed: April 18, 2001
    Publication date: October 25, 2001
    Inventors: Richard Liichang Shao, James William Kortovich, Irwin Charles Lewis, Richard Thomas Lewis
  • Patent number: 6280663
    Abstract: A process for preparing pins for connecting carbon electrodes is presented. In particular, a process for preparing pins for connecting carbon electrodes including the steps of combining calcined coke, a liquid pitch binder and carbon fibers derived from mesophase pitch to form a pinstock blend; extruding the pinstock blend to form a green pinstock; baking the green pinstock to form a carbonized pinstock; and graphitizing the carbonized pinstock by maintaining the carbonized pinstock at a temperature of at least about 2500° C. for no more than about 18 hours is presented. The pins prepared by the inventive process are also presented.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: August 28, 2001
    Assignee: UCAR Carbon Company Inc.
    Inventors: Richard Liichang Shao, James William Kortovich, Irwin Charles Lewis, Richard Thomas Lewis
  • Patent number: 6214158
    Abstract: A curable, high temperature, carbonaceous, cement paste composition comprising a catalyst; a carbon filler present in an amount of about 20 to about 60 wt. %; a polymerizable monomeric system present in an amount of about 7 to about 30 wt. % comprising a dialkyl ester of an aromatic tetracarboxylic acid, an aromatic diamine, and a monoalkyl ester of an acid selected from the group consisting of 5-norbornene-2,3-dicarboxylic acid and phthalic acid; and a furan solvent present in an amount of about 20 to about 60 wt. %. The most preferred embodiment comprising a monomeric system comprising a dimethyl ester of 3,3′,4,4′-benzophenonetetracarboxylic acid, 2,2′-bis (4-[4-aminophenoxyl]phenyl)propane and a monomethyl ester of 5-norbornene-2,3-dicarboxylic acid with furfuryl alcohol and a catalytic solution of about 50% ZnCl2, has a glass transition temperature of about 280° C. after curing by heating at about 2° C./minute to about 240° C. and holding for about 2 hours.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: April 10, 2001
    Assignee: UCAR Carbon Company Inc.
    Inventors: Charles Chi-Chieh Chiu, Irwin Charles Lewis, Richard Thomas Lewis
  • Patent number: 6133255
    Abstract: Tricyclic pyridin-2-one analogues which are ligands for GABA.sub.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: October 17, 2000
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Timothy Harrison, Richard Thomas Lewis, Christopher Richard Moyes, Alan Nadin, Andrew Pate Owens
  • Patent number: 5974643
    Abstract: An industrial robot has a mounting bracket and a servo motor secured to the mounting bracket for rotation relative thereto about a first axis offset from the vertical by 60.degree.. A sensor plate is mounted on one end of the motor, a position sensor is mounted on the bracket and interacts with the sensor plate to sense the rotational home and overtravel positions of the motor. A tool changer is coaxially mounted on the other end of the motor and has means for mounting a turret for coaxial rotation by the motor. A turret having a plurality of circumferentially-spaced tools is mounted on the tool changer for operation on a second axis offset 60.degree. from the first axis, such that each tool is rotatable about the first axis to a vertical working position.
    Type: Grant
    Filed: June 25, 1998
    Date of Patent: November 2, 1999
    Assignee: General Motors Corporation
    Inventors: Timonthy Charles Hays, Thomas Lewis Richter, Dale Peter Holod, Jerome Frank Kamyszek
  • Patent number: 5811431
    Abstract: The present invention relates to compounds of formula (I), wherein n is zero, 1, 2 or 3; R represents C.sub.1-6 alkyl, C.sub.1-6 alkoxy, hydroxy, halogen, cyano, trifluoromethyl SO.sub.2 C.sub.1-6 alkyl, NR.sup.a R.sup.b, NR.sup.a COR.sup.b or CONR.sup.a R.sup.b, where R.sup.a and R.sup.b are each H, C.sub.1-4 alkyl, phenyl or trifluoromethyl; R.sup.1 represents phenyl optionally substituted by 1, 2 or 3 of C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkylC.sub.1-4 alkyl, --O(CH.sub.2).sub.p O-- (where p is 1 or 2), halogen, cyano, nitro, trifluoromethyl, trimethylsilyl, OR.sup.a, SR.sup.a, SOR.sup.a, SO.sub.2 R.sup.a, NR.sup.a R.sup.b, NR.sup.a COR.sup.b, NR.sup.a CO.sub.2 R.sup.b, COR.sup.a, CO.sub.2 R.sup.a or CONR.sup.a R.sup.b ; naphthyl; benzhydryl; or benyl, where the naphthyl group or each phenyl moiety of benzyl and benzhydryl may be substituted by C.sub.1-6 alkyl, C.sub.1-6 alkoxy, halogen or trifluoromethyl; R.sup.
    Type: Grant
    Filed: January 7, 1997
    Date of Patent: September 22, 1998
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Tamara Ladduwahetty, Richard Thomas Lewis, Angus Murray MacLeod, Kevin John Merchant
  • Patent number: 5760018
    Abstract: The present invention is directed to certain compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, A.sup.1, A.sup.2, X, m and n are defined herein. The compounds of this invention are tachykinin receptor antagonists and are of particular use in the treatment of pain, inflammation, migraine and emesis.
    Type: Grant
    Filed: July 11, 1996
    Date of Patent: June 2, 1998
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Raymond Baker, Richard Thomas Lewis, Angus Murray MacLeod, Graeme Irvine Stevenson
  • Patent number: 5719149
    Abstract: The present invention relates to compounds of formula (I) wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are selected from a variety of suitable aromatic substituents; R.sup.6 is hydrogen, C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkylC.sub.1-4 alkyl, phenyl, or C.sub.2 -alkyl substituted by C.sub.1-4 alkoxy or hydroxy; R.sup.7 is hydrogen, C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkylC.sub.1-4 alkyl, phenyl, C.sub.2-4 alkyl substituted by C.sub.1-4 alkoxy or hydroxy, or the group C(.dbd.NR.sup.c)NR.sup.a R.sup.b ; or R.sup.6 and R.sup.7, together with the nitrogen atom to which they are attached, form an optionally substituted saturated heterocyclic ring of 4 to 7 ring atoms which may optionally contain in the ring one oxygen or sulphur atom or a group selected from NR.sup.8, S(O) or S(O).sub.2 ; or R.sup.6 and R.sup.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: February 17, 1998
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Paul Finke, Timothy Harrison, Richard Thomas Lewis, Angus Murray MacLeod, Andrew Pate Owens