Abstract: Disclosed herein are antimicrobial compounds, polymorphic forms, compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).

Abstract: An apparatus for treating a vehicle surface with a fluid has a rotation device pivotably mounted about an axis of rotation, and a fluid supply device disposed concentrically with respect to the rotation device and which has an inlet opening for the supply of fluid. The apparatus is characterized in that a groove is formed in the fluid supply device. The groove is fluidically connected to the inlet opening and extends in the circumferential direction with respect to the axis of rotation over a limited circumferential angle range of the fluid supply device. The rotation device has a plurality of separate fluid channels, each of which opens into openings. The openings are disposed such that irrespective of the angular position of the rotation device to the fluid supply device with respect to the axis of rotation, and at least one of the openings of the rotation device is fluidically connected to the groove of the fluid supply device.

Abstract: Motor vehicle components are subjected to continuous vibration during operation of the motor vehicle, and hydrolysis resistant (HR) glass fibres are included in polyamide compositions to improve the operational stability of the components.

Abstract: A device (1) for cleaning the external auditory canal, which device (1) includes a guide sleeve (30), with a proximal outlet portion (31) for partial insertion into the auditory canal, and an instrumentation rod (10) that can be guided axially through the guide sleeve (30). At a proximal end region, the instrumentation rod (10) has a cleaner (20) with at least one circumferentially extending cleaning element (21) which is elastically expandable in a radial direction. An internal cross section of the proximal outlet portion (31) is smaller than an external cross section of the cleaning element (21) in a radially expanded state.

Abstract: The present invention relates to heat-stabilized polyamide 66-based compositions containing reinforcing materials based on at least one semiaromatic polyamide, at least one phenolic antioxidant and at least one polyhydric alcohol, to molding materials producible therefrom and in turn to injection-molded, blow-molded or extruded articles of manufacture producible therefrom.

Abstract: The present invention relates to heat-stabilized polyamide 66-based compositions containing reinforcing materials based on at least one semiaromatic polyamide, at least one copper halide and at least one polyhydric alcohol, to molding materials producible therefrom and in turn to injection-molded, blow-molded or extruded articles of manufacture producible therefrom.

Abstract: A vehicle washing system for cleaning a vehicle located in a washing zone of the vehicle washing system includes a device for creating a foam curtain extending substantially transversely to a longitudinal direction of the vehicle washing system. The device is arranged on the vehicle washing system in such a way as to be vertically adjustable.

Abstract: An apparatus for treating a vehicle surface with a fluid has a rotation device pivotably mounted about an axis of rotation, and a fluid supply device disposed concentrically with respect to the rotation device and which has an inlet opening for the supply of fluid. The apparatus is characterized in that a groove is formed in the fluid supply device. The groove is fluidically connected to the inlet opening and extends in the circumferential direction with respect to the axis of rotation over a limited circumferential angle range of the fluid supply device. The rotation device has a plurality of separate fluid channels, each of which opens into openings. The openings are disposed such that irrespective of the angular position of the rotation device to the fluid supply device with respect to the axis of rotation, and at least one of the openings of the rotation device is fluidically connected to the groove of the fluid supply device.

Abstract: Motor vehicle components are subjected to continuous vibration during operation of the motor vehicle, and hydrolysis resistant (HR) glass fibres are included in polyamide compositions to improve the operational stability of the components.

Abstract: Motor vehicle components are subjected to continuous vibration during operation of the motor vehicle, and hydrolysis resistant (HR) glass fibres are included in nylon compositions to improve the operational stability of the components.

Abstract: A compound of formula (II), and a method of preparation thereof, for use as a smooth muscle cell (SMC) proliferation-inhibiting drug: wherein: R1 to R6 are —H, —F, —CH3, —CF3, —CF2CH3, —OCH3, —COCH3, —C4H9, —COOC2H5, or —C6H5, or two vicinal residues from R1 to R6 form a saturated or unsaturated carbocyclic ring together with the two carbon atoms to which they are attached; R7 is OH, allyloxy, propargyl-oxy, 2,2-dimethylpropanoyloxy (pivaloyloxy), butanoyloxy, 3-methylbutanoyloxy, 2-buten-oyloxy, 2-methyl-2-butenoyloxy, 3-methyl-2-butenoyloxy, isopentanoyloxy, 2-ethylbutanoyl-oxy, 3,3-dimethylbutanoyloxy, cyclopropylcarbonyloxy, cyclobutylcarbonyloxy, cyclo-pentylcarbonyloxy, cyclopentenylcarbonyloxy, cyclohexylcarbonyloxy, cyclo-hexenylcarbonyloxy, adamantylethanoyloxy, 3-phenylpropenoyloxy (cinnamyloyloxy), 2-methylbenzoyloxy, or naphthoyloxy; wherein, in ring A and/or B, one or more carbon ring atoms are optionally replaced by heteroatoms; wherein the compounds of formula (II) are obtained by combining

Abstract: A method of inducing differentiation of mammalian cells into cardiomyocyte-like cells by contacting the mammalian cell with a triazine compound of formula (I), wherein X is independently —NR4—or —O—, R4 is hydrogen or C1-6-alkyl; R1 is hydroxy, C1-6-alkyl, C1-6-alkoxy, carboxy, C1-6-alkoxycarbonyl, halo, cyano, nitro, formyl, amino, C1-6-alkylamino, or di-C1-6-alkylamino, the C1-6-alkyl or -alkoxy residue being optionally substituted with one or more R5 substituents selected from hydroxy, halo, cyano, and nitro; n is 0 to 5; R2 is hydrogen, aryl, heteroaryl, or C1-6-alkyl, the aryl or heteroaryl residue being optionally substituted with one or more R1 substituents, and where the C1-6-alkyl is optionally further substituted with one or more R5 substituents; and R3 is selected from hydrogen, halo, NR4R7, OR7, SR7, and R7, where the same options apply for R7 as for R2; with the proviso that the compound of formula (I) is not 3-[(4,6-diphenoxy-1,3,5-triazin-2-yl)amino]benzoic acid.

Abstract: Polyamide-based compositions may be heat stabilized by compositions of iron oxalate and diapentaerythritol. The heat stabilized polyamides may be used for production of moulding materials which may be injection moulded, blow-moulded, or extruded to provide articles of manufacture.

Abstract: Heat-stabilized polyamide-based compositions include a stabilizing system of at least one salt of citric acid and dipentaerythritol. The heat stabilized polyamide compositions are suitable for moulding materials, which in turn may be injection moulded, blow moulded, or extruded to produce articles of manufacture.

Abstract: The present invention relates to a method for preparing low-chloride lithium hexafluorophosphate starting from lithium fluoride and phosphorus pentafluoride and use thereof in an electrolyte.

Abstract: Audio processing systems and corresponding methods are disclosed, wherein the audio processing system comprises at least one of an analog portion and a digital portion.

Abstract: Embodiments related to line testing are described and depicted. A digital subscriber line testing apparatus comprises a plurality of resistors and a switching device. The switching device comprises first and second signal inputs to couple the switching device to a signal generator output, and a plurality of wire terminals. The switching device is configured to switch the plurality of resistors into a first switching state and a second switching state.

Abstract: A method of inducing differentiation of mammalian cells into cardiomyocyte-like cells by contacting the mammalian cell with a triazine compound of formula (I), wherein X is independently —NR4— or —O—, R4 is hydrogen or C1-6-alkyl; R1 is hydroxy, C1-6-alkyl, C1-6-alkoxy, carboxy, C1-6-alkoxycarbonyl, halo, cyano, nitro, formyl, amino, C1-6-alkylamino, or di-C1-6-alkylamino, the C1-6-alkyl or -alkoxy residue being optionally substituted with one or more R5 substituents selected from hydroxy, halo, cyano, and nitro; n is 0 to 5; R2 is hydrogen, aryl, heteroaryl, or C1-6-alkyl, the aryl or heteroaryl residue being optionally substituted with one or more R1 substituents, and where the C1-6-alkyl is optionally further substituted with one or more R5 substituents; and R3 is selected from hydrogen, halo, NR4R7, OR7, SR7, and R7, where the same options apply for R7 as for R2; with the proviso that the compound of formula (I) is not 3-[(4,6-diphenoxy-1,3,5-triazin-2-yl)amino]benzoic acid.

Abstract: The subject of the invention at hand are novel, a little basic, fluorinated pentafluorophenyl imide anions, which can be used as anions in ionic liquids. Methods for producing ionic liquids are described, which contain these novel pentafluorophenyl imide ions as anions, as well as quaternary organic ammonium ions, guanidinium ions, N-organo-pyridinium ions, imidazolium, imidazolidinium or benzimidazolidinium ions, alkyl-alkylidene phosphoranes or aryl-alkylidene phosphoranes as cations. Alternative methods according to the present invention provide ionic liquids through reaction of ketene N,N-diacetals or alkyl or aryl-alkylidene phosphoranes with acids. The ionic liquids according to the present invention are suitable, for example, as solvents for syntheses, as mobile and/or stationary phase in chromatography, as electrolyte systems for batteries, galvanic elements, fuel cells and rechargeable battery packs.

Abstract: The present invention provides new lithium salts comprising pentafluorophenylamide anions following the general formula Li+[N(SO2—R)(C6F5)]?, which are optionally present as solvent-free complexes. R is hereby selected from fluorine, linear or branched acyclic or cyclic alkyl groups with 1 to 20 carbon atoms which are not fluorinated, partially fluorinated or fully fluorinated; or not fluorinated, partially fluorinated or fully fluorinated aryl or benzyl groups with 1 to 20 carbon atoms. The lithium salts according to the present invention are produced by reacting the corresponding NH acid of the pentafluorophenylamide with one equivalent of lithium bis(trimethylsilyl)amide or lithium organyl, wherein the reaction is carried out advantageously in the presence of apolar aprotic solvents. In this way, lithium salts in the form of solvent-free complexes are obtained. These solvent-free lithium complexes are thermally, electrochemically and against oxidation stable and comprise a high ionic conductivity.