Abstract: A composition for making a core for use in a moulding or casting process, a core comprising said composition, and a mould for producing an article by high pressure die casting or semi-solid casting. The composition comprises a particulate refractory material, a binder composition comprising at least one hydrophilic polymer, comprising at least one polysaccharide or polysaccharide derivative; and at least one pozzolanic additive. The mould comprises a core for defining an internal cavity of the article and the core comprises a solidified core composition. The solidified core composition comprises a particulate refractory material and a binder composition, degrades in water such that a cylinder of the solidified core composition having a maximum height of 80 mm and a maximum diameter of 50 mm disintegrates in no more than 10 minutes when immersed in water at a temperature of 20° C. and stirred at a speed of 60 rpm, and has a flexural strength of at least 300 N/cm2.

Abstract: Methods of purifying adenovirus that can be performed on a large scale. The methods purify adenovirus from an adenovirus-containing sample comprising or derived from a host cell population by clarifying the sample, wherein clarification comprises depth filtration followed by microfiltration; processing the clarified sample by anion exchange chromatography; and processing the anion exchange product by tangential flow filtration (TFF) to provide a TFF product.

Abstract: A mounting system for mounting a photovoltaic module onto at least one mounting rail. The mounting system comprises a frame for the photovoltaic module with at least one opening or protrusion at a lateral side or a bottom side of the frame, the bottom side being opposite to light incidence side of the photovoltaic module. The mounting system further comprises a plurality of mounting elements, each comprising a first portion and a second portion for securing the frame to the at least one mounting rail, the first portion defining a hook-like engagement portion to hook into the opening or the protrusion or the bottom side of the frame to provide an interlocking connection, the second portion enabling a secure fixation to the at least one mounting rail.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: A mounting system for mounting a photovoltaic module onto at least one mounting rail. The mounting system comprises a frame for the photovoltaic module with at least one opening or protrusion at a lateral side or a bottom side of the frame, the bottom side being opposite to light incidence side of the photovoltaic module. The mounting system further comprises a plurality of mounting elements, each comprising a first portion and a second portion for securing the frame to the at least one mounting rail, the first portion defining a hook-like engagement portion to hook into the opening or the protrusion or the bottom side of the frame to provide an interlocking connection, the second portion enabling a secure fixation to the at least one mounting rail.

Abstract: The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography.

Abstract: The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.

Abstract: A refractory coating for producing mold coatings by application to inorganically or organically-bound molding materials in lost molds or to cores for iron and steel casting is disclosed. The refractory coating can have a proportion by weight of 0.001% or more and less than 1% of inorganic hollow bodies, which partially or fully consist of crystalline material and have a softening point of 1000° C. or higher.

Abstract: The present invention relates to a refractory coating for producing mold coatings by application to inorganically or organically-bound molding materials in lost molds or to cores for iron and steel casting, wherein the ready-to-use refractory coating has proportion by weight of 0.001% or more and less than 1% of inorganic hollow bodies, which partially or fully consist of crystalline material and have a softening point of 1000° C. or higher.

Abstract: A refractory coating for producing mold coatings by application to inorganically or organically-bound molding materials in lost molds or to cores for iron and steel casting is disclosed. The refractory coating can have a proportion by weight of 0.001% or more and less than 1% of inorganic hollow bodies, which partially or fully consist of crystalline material and have a softening point of 1000° C. or higher.

Abstract: The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography.

Abstract: A partially redundant, contactless pedal-travel sensor is used for controlling a vehicle. This pedal travel sensor generates at least two redundant signals using a contactless sensor and an electronic circuit. These signals are fed to a control and/or regulating unit, where they are subjected to a plausibility check to detect a faulty pedal-travel sensor. To improve safety during a failure of a pedal-travel sensor and to improve the diagnostic options, it is provided that a specific position of the pedal is detected by a switch and a signal is generated by the switch. Then a plausibility comparison of the signal generated by the switch with the signals generated by the pedal-travel sensor is performed.