Patents by Inventor Thomas Linsky

Thomas Linsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interleukin-2 Receptor Beta (IL-2RB) Binding Polypeptides
    Publication number: 20230340071
    Abstract: The present invention is related to, inter alia, de novo IL-2R13 binding polypeptides.
    Type: Application
    Filed: March 12, 2021
    Publication date: October 26, 2023
    Applicants: Neoleukin Therapeutics, Inc., University of Washington
    Inventors: Daniel Adriano Silva Manzano, Alfredo Quijano Rubio, Jesus Renan Vergara Gutierrez, Thomas Linsky, Jorgen Nelson
  • Modified biotin-binding proteins for immobilization
    Patent number: 11781177
    Abstract: Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: October 10, 2023
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: Satwik Kamtekar, Lubomir Sebo, Leewin Chern, Thomas Linsky, Jeremiah Hanes, Erik Miller, Ying Yang, Stephen Yue
  • METHODS AND COMPOSITIONS FOR DELIVERY OF MOLECULES AND COMPLEXES TO REACTION SITES
    Publication number: 20220364168
    Abstract: The present invention provides methods, compositions, and systems for distributing molecules and complexes into reaction sites. In particular, the methods, compositions, and systems of the present invention result in loading of polymerase enzyme complexes into a predetermined number of reaction sites, including nanoscale wells.
    Type: Application
    Filed: April 12, 2022
    Publication date: November 17, 2022
    Inventors: Jaime Juan Benitez-Marzan, Natasha Popovich, Lei Sun, Satwik Kamtekar, Keith Bjornson, Jeremiah Hanes, Karl Voss, Erik Miller, Thomas Linsky, Leewin Chern
  • MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION
    Publication number: 20200354783
    Abstract: Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.
    Type: Application
    Filed: April 6, 2020
    Publication date: November 12, 2020
    Inventors: Satwik Kamtekar, Lubomir Sebo, Leewin Chern, Thomas Linsky, Jeremiah Hanes, Erik Miller, Ying Yang, Stephen Yue
  • Modified biotin-binding proteins for immobilization
    Patent number: 10655168
    Abstract: Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 19, 2020
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: Satwik Kamtekar, Lubomir Sebo, Leewin Chern, Thomas Linsky, Jeremiah Hanes, Erik Miller, Ying Yang, Stephen Yue
  • METHODS AND COMPOSITIONS FOR DELIVERY OF MOLECULES AND COMPLEXES TO REACTION SITES
    Publication number: 20200002765
    Abstract: The present invention provides methods, compositions, and systems for distributing molecules and complexes into reaction sites. In particular, the methods, compositions, and systems of the present invention result in loading of polymerase enzyme complexes into a predetermined number of reaction sites, including nanoscale wells.
    Type: Application
    Filed: June 28, 2019
    Publication date: January 2, 2020
    Inventors: Jaime Juan Benitez-Marzan, Natasha Popovich, Lei Sun, Satwik Kamtekar, Keith Bjornson, Jeremiah Hanes, Karl Voss, Erik Miller, Thomas Linsky, Leewin Chern
  • MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION
    Publication number: 20190249237
    Abstract: Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.
    Type: Application
    Filed: December 21, 2018
    Publication date: August 15, 2019
    Inventors: Satwik Kamtekar, Lubomir Sebo, Leewin Chern, Thomas Linsky, Jeremiah Hanes, Erik Miller, Ying Yang, Stephen Yue