Patents by Inventor Thomas Livelli

Thomas Livelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120276545
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: May 1, 2012
    Publication date: November 1, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20120231541
    Abstract: Disclosed are assays, methods, and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. In particular, whether a test compound has the effect to prolong the Q-T interval as measured by an electrocardiogram in a human. The assays, methods, and kits disclosed herein make use of the binding interaction between novel fluorescent tracers and the hERG K+ channel, and the propensity of a test compound to influence that binding interaction.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 13, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: David Piper, Stephen Hess, Mohammed Saleh Shekhani, Thomas Livelli, Zhong Zhong, Steve Duff, Kurt Vogel
  • Patent number: 8133695
    Abstract: Disclosed are assays, methods, and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. In particular, whether a test compound has the effect to prolong the Q-T interval as measured by an electrocardiogram in a human. The assays, methods, and kits disclosed herein make use of the binding interaction between novel fluorescent tracers and the hERG K+ channel, and the propensity of a test compound to influence that binding interaction.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: March 13, 2012
    Assignee: Life Technologies Corporation
    Inventors: David Piper, Kurt Vogel, Mohammed Saleh Shekhani, Stephen Hess, Steve Duff, Thomas Livelli, Zhong Zhong
  • Publication number: 20110275101
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: May 6, 2011
    Publication date: November 10, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • Patent number: 7960101
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: June 14, 2011
    Assignee: Life Technologies Corporation
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20100203561
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: January 11, 2010
    Publication date: August 12, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20090253148
    Abstract: Disclosed are assays, methods, and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. In particular, whether a test compound has the effect to prolong the Q-T interval as measured by an electrocardiogram in a human. The assays, methods, and kits disclosed herein make use of the binding interaction between novel fluorescent tracers and the hERG K+ channel, and the propensity of a test compound to influence that binding interaction.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 8, 2009
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: David Piper, Stephen Hess, Mohammed Saleh Shekhani, Thomas Livelli, Zhong Zhong, Steve Duff, Kurt Vogel
  • Publication number: 20080248516
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: June 12, 2008
    Publication date: October 9, 2008
    Applicant: INVITROGEN CORPORATION
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20080081327
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: July 10, 2007
    Publication date: April 3, 2008
    Applicant: INVITROGEN CORPORATION
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20060148007
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: February 27, 2006
    Publication date: July 6, 2006
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Patent number: 7045281
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Cell & Molecular Technologies, Inc.
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Publication number: 20040058329
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: September 20, 2002
    Publication date: March 25, 2004
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Patent number: 4618408
    Abstract: A casting apparatus for receiving electrophoretic gel trays is disclosed. The casting apparatus includes a pair of spaced apart seal elements which are movable with respect to one another to provide one or, more openings of varying size to receive a corresponding gel tray therein. The open ends of the gel tray are sealed by the seal elements so that hot argrose or polyacrylamide gel may be poured into the gel tray for forming a gel layer of predetermined thickness. The seal elements are maintained in sealing engagement with the open ends of the gel trays by means of a rod frictionally engaged between a portion of the housing forming the casting apparatus and one of the seal elements.
    Type: Grant
    Filed: November 29, 1984
    Date of Patent: October 21, 1986
    Assignee: Lab Stuff, Inc.
    Inventors: Richard Malavarca, Thomas Livelli
  • Patent number: D290510
    Type: Grant
    Filed: November 29, 1984
    Date of Patent: June 23, 1987
    Assignee: Lab Stuff, Inc.
    Inventors: Richard Malavarca, Thomas Livelli