Patents by Inventor Thomas Loisel

Thomas Loisel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7439030
    Abstract: The present invention describes a method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors and an assay to screen molecules that are active on these membrane receptors.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: October 21, 2008
    Assignees: Valorisation-Recherche, Limited Partnership, Centre National de la Recherche Scientifique
    Inventors: Michel Bouvier, Thomas Loisel, Stefano Marullo, Pierre Boulanger, Arthur Donny Strosberg
  • Publication number: 20060281150
    Abstract: A method of determining whether a membrane receptor expressed in recombinant extracellular baculoviruses is active, the method comprising: providing recombinant extracellular baculoviruses expressing a membrane receptor; contacting the extracellular baculoviruses with a ligand to the membrane receptor; and determining whether binding of the ligand to the receptor occurs, wherein said binding is an indication that the receptor is active.
    Type: Application
    Filed: April 25, 2006
    Publication date: December 14, 2006
    Applicant: Centre National De La Recherche Scientifique
    Inventors: Michel Bouvier, Thomas Loisel, Stefano Marullo, Pierre Boulanger, Arthur Strosberg
  • Patent number: 7078189
    Abstract: Method of producing a recombinant membrane receptor protein by introducing a baculovirus expression vector encoding the membrane receptor protein into a host cell, culturing the resultant host cell for a sufficient time to permit expression of the membrane receptor protein and baculovirus viral particles and separating the cells from the viral particles. The baculovirus viral particles are then recovered.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: July 18, 2006
    Assignees: Centre National de la Recherche Scientifique, Valorisation-Recherche, Limited Partnership
    Inventors: Michel Bouvier, Thomas Loisel, Stefano Marullo, Pierre Boulanger, Arthur Donny Strosberg
  • Publication number: 20060014687
    Abstract: A bone delivery conjugate having a structure selected from the group consisting of: A) X-Dn-Y-protein-Z; and B) Z-protein-Y-Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and Dn is a poly aspartate wherein n=10 to 16. Compositions comprising same and methods of use thereof.
    Type: Application
    Filed: April 21, 2005
    Publication date: January 19, 2006
    Inventors: Philippe Crine, Guy Boileau, Isabelle Lemire, Thomas Loisel
  • Publication number: 20040142471
    Abstract: The present invention relates to a method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors and an assay to screen molecules that are active on these membrane receptors.
    Type: Application
    Filed: December 11, 2003
    Publication date: July 22, 2004
    Applicants: Valorisation-Recherche, Limited Partnership, Centre National De La Recherche Scientifique
    Inventors: Michel Bouvier, Thomas Loisel, Stefano Marullo, Pierre Boulanger, Arthur Donny Strosberg
  • Patent number: 6713278
    Abstract: Method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors and an assay to screen molecules that are active on these membrane receptors.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: March 30, 2004
    Assignees: Valorisation-Recherche, Limited Partnership, Centre National de la Recherche ScientifiquĂȘ
    Inventors: Michel Bouvier, Thomas Loisel, Stefano Marullo, Pierre Boulanger, Arthur Donny Strosberg