Patents by Inventor Thomas Ludwig

Thomas Ludwig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11912780
    Abstract: This invention provides a method for depleting a subject's hematopoietic stem cells comprising administering to the subject an effective amount of a radiolabeled anti-CD45 antibody, such as 131I-BC8 or 225Ac-BC8. This invention also provides a method for treating a subject afflicted with a non-cancerous disorder treatable via genetically edited cell therapy comprising (i) administering to the subject an amount of a radiolabeled anti-CD45 antibody effective to deplete the subject's hematopoietic stem cells, and (ii) after a suitable time period, performing the therapy on the subject to treat the subject's disorder. Finally, this invention provides articles of manufacture for performing the subject methods.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 27, 2024
    Assignee: ACTINIUM PHARMACEUTICALS, INC.
    Inventors: Mark Berger, Keisha Thomas, Sandesh Seth, Dale Lincoln Ludwig
  • Publication number: 20230323422
    Abstract: This disclosure provides a novel method of controlling the glycosylation profile of a protein during production. The disclosure also provides a novel method of improving protein yield while controlling the glycosylation profile of a protein.
    Type: Application
    Filed: August 13, 2021
    Publication date: October 12, 2023
    Applicant: Bristol-Myers Squibb Company
    Inventors: Amanda Morgan LEWIS, Alison Gene-Wei LEE, Nancy Ann LAMON, Terrance Wayne CARONE, II, Ronald Charles BATES, Richard Thomas LUDWIG
  • Publication number: 20230313259
    Abstract: This disclosure provides a novel method of controlling the glycosylation profile of a protein during production. The disclosure also provides a novel method of improving protein yield while controlling the glycosylation profile of a protein.
    Type: Application
    Filed: August 13, 2021
    Publication date: October 5, 2023
    Applicant: Bristol-Myers Squibb Company
    Inventors: Amanda Morgan LEWIS, Daniel Robert MASKAS, Eric Richard GARR, Diane Kay WORRELL, Richard Thomas LUDWIG
  • Patent number: 11185451
    Abstract: The present invention relates to a method of applying absorbent gelling material (AGM) granules by indirect printing onto an carrier layer for use in an absorbent article, particularly diaper for babies or adults, training pants, pull-up diapers (diaper pants), sanitary napkins, panty liners or the like. These articles typically comprise the carrier layer with the AGM particles together with further layers, making up the complete article.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: November 30, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Horst Blessing, Hans Adolf Jackels, Siegfried Link, Volker Maier, Thomas Ludwig Woschnik, Martin Geoffrey Scaife
  • Patent number: 11176835
    Abstract: In order to provide an aircraft with GLS (GBAS (Ground-Based Augmentation System) Landing System) data packets for a satellite navigation-based automatic landing, the GLS data packets comprising GBAS correction data for a satellite navigation and FAS data that describes a set approach path of the aircraft, SBAS (Satellite-Based Augmentation System) correction data for the satellite navigation are received from an SBAS satellite. The received SBAS correction data are converted into GBAS correction data. The GBAS correction data obtained by the conversion are combined with the FAS data in the GLS data packets. The GLS data packets are transmitted to the aircraft via a radio link.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: November 16, 2021
    Assignee: Deutsches Zentrum fuer Luft- und Raumfahrt e.V.
    Inventors: Thomas Dautermann, Robert Geister, Thomas Ludwig
  • Publication number: 20210265059
    Abstract: The invention provides a method of analysing the consistency of stool, including the steps of: providing stool of an infant, capturing, with a portable device comprising a camera, an image of the stool, providing the captured image to an input layer of a pre-trained convolutional neural network, CNN, processing the captured image using the CNN to obtain, from a final layer of the CNN, a classification vector and to obtain information about a predicted score from the classification vector, wherein at least the final layer of the CNN has been customized so that each element of the classification vector corresponds to a score of a stool analysis scale, and storing information about the predicted store.
    Type: Application
    Filed: May 28, 2019
    Publication date: August 26, 2021
    Applicant: N.V. Nutricia
    Inventors: Damien Luc Dominique Marie Paineau, Agathe Camille Foussat, Thomas Ludwig, Inès Oukid
  • Publication number: 20180261110
    Abstract: In order to provide an aircraft with GLS (GBAS Landing System) data packets for a satellite navigation-based automatic landing, the GLS data packets comprising GBAS (Ground-Based Augmentation System) correction data for a satellite navigation and FAS data that describes a set approach path of the aircraft, SBAS (Satellite-Based Augmentation System) correction data for the satellite navigation are received from an SBAS satellite. The received SBAS correction data are converted into GBAS correction data. The GBAS correction data obtained by the conversion are combined with the FAS data in the GLS data packets. The GLS data packets are transmitted to the aircraft via a radio link.
    Type: Application
    Filed: May 9, 2018
    Publication date: September 13, 2018
    Inventors: Thomas Dautermann, Robert Geister, Thomas Ludwig
  • Publication number: 20170367907
    Abstract: The present invention relates to a method of applying absorbent gelling material (AGM) granules by indirect printing onto an carrier layer for use in an absorbent article, particularly diaper for babies or adults, training pants, pull-up diapers (diaper pants), sanitary napkins, panty liners or the like. These articles typically comprise the carrier layer with the AGM particles together with further layers, making up the complete article.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 28, 2017
    Inventors: Horst BLESSING, Hans Adolf JACKELS, Siegfried LINK, Volker MAIER, Thomas Ludwig WOSCHNIK, Martin Geoffrey SCAIFE
  • Patent number: 9782307
    Abstract: The present invention relates to a method of applying absorbent gelling material (AGM) granules by indirect printing onto an carrier layer for use in an absorbent article, particularly diaper for babies or adults, training pants, pull-up diapers (diaper pants), sanitary napkins, panty liners or the like. These articles typically comprise the carrier layer with the AGM particles together with further layers, making up the complete article.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: October 10, 2017
    Assignee: The Procter & Gamble Company
    Inventors: Horst Blessing, Hans Adolf Jackels, Siegfried Link, Volker Maier, Thomas Ludwig Woschnik, Martin Geoffrey Scaife
  • Patent number: 9717270
    Abstract: The present invention relates to a fermented infant formulae comprising non digestible oligosaccharides for improving intestinal tract health by decreasing protein digestive effort, by decreasing the amount of endogenously formed proteases concomitant with an increased protein digestion, and a reduced protein fermentation.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: August 1, 2017
    Assignee: N.V. Nutricia
    Inventors: Thomas Ludwig, Sylvie Huybers, Evan Abrahamse, Houkje Bouritius
  • Patent number: 9682119
    Abstract: This invention relates to a pea-based protein mixture and use thereof in a liquid nutritional composition, in particular suitable for tube feeding, and further relates to the liquid nutritional composition for providing long-term complete enteral nutrition to patients in need thereof. More specifically, the pea-based protein mixture and the liquid nutritional composition comprising the pea-based protein mixture comprises more than 25 weight % and up to 80 weight % of vegetable protein comprising a source of intact pea protein and a source of intact soy protein. The invention relates further to a method for long-term enteral nutrition of patients in need thereof comprising administering an effective amount of the liquid nutritional composition comprising the pea-based protein mixture, in particular comprising a defined amount of intact pea protein and a second vegetable intact protein, other than pea protein.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: June 20, 2017
    Assignee: N.V. Nutricia
    Inventors: Zandrie Hofman, Rogier Daniël Van Anholt, Wynette Hermina Agnes Kiers, Thomas Ludwig, Claudia Catharina Maria Van Den Braak, Marianne Klebach
  • Publication number: 20170156389
    Abstract: The present invention relates to a fermented infant formulae comprising non digestible oligosaccharides for improving intestinal tract health by decreasing protein digestive effort, by decreasing the amount of endogenously formed proteases concomitant with an increased protein digestion, and a reduced protein fermentation.
    Type: Application
    Filed: February 24, 2017
    Publication date: June 8, 2017
    Applicant: N.V. Nutricia
    Inventors: Thomas LUDWIG, Sylvie HUYBERS, Evan ABRAHAMSE, Houkje BOURITIUS
  • Patent number: 9617327
    Abstract: The present invention relates to a fermented infant formulae comprising non digestible oligosaccharides for improving intestinal tract health by decreasing protein digestive effort, by decreasing the amount of endogenously formed proteases concomitant with an increased protein digestion, and a reduced protein fermentation.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: April 11, 2017
    Assignee: N.V. Nutricia
    Inventors: Thomas Ludwig, Sylvie Huybers, Evan Abrahamse, Houkje Bouritius
  • Patent number: 9492502
    Abstract: A process of producing a composition comprising at least two different proteins is disclosed, of which at least one is a coagulating protein, such as a casein and/or a caseinate, and at least one is an anti-coagulating protein, such as a leguminous protein (for example pea and/or soy) combined or not with whey protein, comprising the steps of: a) heat-sterilizing a first liquid component comprising the coagulating protein, b) heat-sterilizing a second liquid component comprising the anti-coagulating protein, and c) mixing the first component with the second component to obtain a mixture thereof. The obtained mixture is useful as a food constituent having reduced coagulation in the upper gastro-intestinal tract, more in particular in the stomach.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: November 15, 2016
    Assignee: N. V. Nutricia
    Inventors: Claudia Catharina Maria Van den Braak, Thomas Ludwig, Marcel Minor, Rudolph Eduardus Maria Verdurmen, Hilde Ruis
  • Publication number: 20160278414
    Abstract: The present invention relates to a fermented infant or follow on formula comprising non digestible oligosaccharides for decreasing duration of crying, reducing crying episodes, and incidence of colics in infants.
    Type: Application
    Filed: November 4, 2014
    Publication date: September 29, 2016
    Applicant: N.V. Nutricia
    Inventors: Thomas LUDWIG, Houkje BOURITIUS, Donghui YU
  • Publication number: 20160213527
    Abstract: Absorbent articles such as disposable diapers, incontinent briefs, diaper holders, training pants and the like, having elastomeric side panels and a fastening system that provides the user with different options as to how the absorbent article may be fitted to and removed from the wearer. The absorbent articles allow the wearer to choose between conventional and pull-on diaper configurations, or combinations thereof, and properly and comfortably fit a large range of wearer sizes. Further, the absorbent articles can be pulled on and/or off as a pant.
    Type: Application
    Filed: April 5, 2016
    Publication date: July 28, 2016
    Inventors: Gary Dean LaVON, Bret Darren SEITZ, Masaharu NISHIKAWA, Bryan Keith WAYE, Thomas Ludwig WOSCHNIK, Yoichiro YAMAMOTO, Thomas TOMBUELT, Hans Adolf JACKELS
  • Patent number: 9376764
    Abstract: The present invention relates to a configuration and in particular a physical vapor transport growth system for simultaneously growing more than one silicon carbide (SiC) bulk crystal. Furthermore, the invention relates to a method for producing such a bulk SiC crystal. A physical vapor transport growth system for simultaneously growing more than one SiC single crystal boule comprises a crucible containing two growth compartments for arranging at least one SiC seed crystal in each of them, and a source material compartment for containing a SiC source material, wherein said source material compartment is arranged symmetrically between said growth compartments and is separated from each of the growth compartments by a gas permeable porous membrane.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: June 28, 2016
    Assignee: SiCrystal AG
    Inventors: Thomas Ludwig Straubinger, Michael Vogel, Andreas Wohlfart, Erwin Schmitt
  • Publication number: 20160089400
    Abstract: The present invention relates to fermentation of milk-derived nutritional compositions to increase thiol protease inhibitor activity, and uses thereof with the products obtained.
    Type: Application
    Filed: April 8, 2014
    Publication date: March 31, 2016
    Applicant: N.V. NUTRICIA
    Inventors: Ingrid Brunhilde RENES, Thomas LUDWIG, Houkje BOURITIUS, Johanna Maria LAMBERT, Sylvie HUYBERS, Evan ABRAHAMSE
  • Publication number: 20160050960
    Abstract: The present invention relates to fermented nutritional compositions comprising non-digestible oligosaccharides for improving the bioavailability of iron and preventing or treating of iron deficiency, in particular for infants and young children or pregnant women.
    Type: Application
    Filed: March 24, 2014
    Publication date: February 25, 2016
    Applicant: N.V. Nutricia
    Inventors: Claudia Catharina Maria VAN DEN BRAAK, Thomas LUDWIG, Houkje BOURITIUS
  • Publication number: 20160044945
    Abstract: The present invention relates to fermented nutritional compositions comprising high concentration of lactosem such as 6 grams per 100 ml, and optionally non-digestible oligosaccharides, such as galactooligosaccharides or fructooligosaccharides for improving the bioavailability of iron and preventing or treating of iron deficiency (anaemia), in particular for infants and young children or pregnant women. In another aspect of the invention, the nutritional composition are used for preventing cognitive disorders and/or socio-emotional disorders in an infant and/or young child.
    Type: Application
    Filed: March 24, 2014
    Publication date: February 18, 2016
    Applicant: N.V. NUTRICIA
    Inventors: Claudia Catharina Maria VAN DEN BRAAK, Thomas LUDWIG, Houkje BOURITIUS