Patents by Inventor Thomas M. Malvar

Thomas M. Malvar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117374
    Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
    Type: Application
    Filed: October 30, 2023
    Publication date: April 11, 2024
    Inventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
  • Patent number: 11840700
    Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: December 12, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
  • Publication number: 20230348543
    Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
    Type: Application
    Filed: May 17, 2023
    Publication date: November 2, 2023
    Inventors: James A. BAUM, David J. BOWEN, Catherine A. CHAY, David J. CHI, William P. CLINTON, Crystal L. DART, Leigh ENGLISH, Stanislaw FLASINSKI, Victor M. GUZOV, Kevin A. JARRELL, Uma R. KESANAPALLI, Thomas M. MALVAR, Robert M. MCCARROLL, Jason S. MILLIGAN, Jay P. MORGENSTERN, Deborah G. RUCKER, Sara A. SALVADOR, Temple F. SMITH, Carlos E. SOTO, Collin M. STULTZ, Brian M. TURCZYK, Ty T. VAUGHN, Moritz W.F. VON RECHENBERG
  • Patent number: 11702455
    Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: July 18, 2023
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, David J. Bowen, Catherine A. Chay, David J. Chi, William P. Clinton, Crystal L. Dart, Leigh English, Stanislaw Flasinski, Victor M. Guzov, Kevin A. Jarrell, Uma R. Kesanapalli, Thomas M. Malvar, Robert M. McCarroll, Jason S. Milligan, Jay P. Morgenstern, Deborah G. Rucker, Sara A. Salvador, Temple F. Smith, Carlos E. Soto, Collin M. Stultz, Brian M. Turczyk, Ty T. Vaughn, Moritz W. F. Von Rechenberg
  • Publication number: 20200369733
    Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
    Type: Application
    Filed: June 5, 2020
    Publication date: November 26, 2020
    Inventors: James A. BAUM, David J. BOWEN, Catherine A. CHAY, David J. CHI, William P. CLINTON, Crystal L. DART, Leigh ENGLISH, Stanislaw FLASINSKI, Victor M. GUZOV, Kevin A. JARRELL, Uma R. KESANAPALLI, Thomas M. MALVAR, Robert M. MCCARROLL, Jason S. MILLIGAN, Jay P. MORGENSTERN, Deborah G. RUCKER, Sara A. SALVADOR, Temple F. SMITH, Carlos E. SOTO, Collin M. STULTZ, Brian M. TURCZYK, Ty T. VAUGHN, Moritz W.F.F. VON RECHENBERG
  • Patent number: 10793869
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: October 6, 2020
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards M. Allen, Larry A Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
  • Patent number: 10772276
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: September 15, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Patent number: 10703782
    Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: July 7, 2020
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, David J. Bowen, Catherine A. Chay, David J. Chi, William P. Clinton, Crystal L. Dart, Leigh English, Stanislaw Flasinski, Victor M. Guzov, Kevin A. Jarrell, Uma R. Kesanapalli, Thomas M. Malvar, Robert M. McCarroll, Jason S. Milligan, Jay P. Morgenstern, Deborah G. Rucker, Sara A. Salvador, Temple F. Smith, Carlos E. Soto, Collin M. Stultz, Brian M. Turczyk, Ty T. Vaughn, Moritz W. F. Von Rechenberg
  • Publication number: 20180263205
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Application
    Filed: March 9, 2018
    Publication date: September 20, 2018
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Patent number: 9976139
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: May 22, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • Patent number: 9913487
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: March 13, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Publication number: 20180007856
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Application
    Filed: June 10, 2013
    Publication date: January 11, 2018
    Applicant: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Publication number: 20180002713
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Application
    Filed: June 29, 2017
    Publication date: January 4, 2018
    Inventors: Edwards M. ALLEN, Larry A. GILBERTSON, Sara E. HEISEL, Shihshieh HUANG, Elysia K. KRIEGER, Thomas M. MALVAR
  • Publication number: 20170233755
    Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Applicant: Monsanto Technology LLC
    Inventors: Mark Scott ABAD, Pranesh BADAMI, Amarjit BASRA, Erin BELL, Christopher P. BONIN, Paolo CASTIGLIONI, R. Eric CERNY, Jaishree M. CHITTOOR, Paul CHOMET, Todd DEZWAAN, Stephen DUFF, Michael D. EDGERTON, Barry S. GOLDMAN, Balasulojini KARUNANANDAA, Kempagangaiah KRISHNAMURTHY, Ping LI, Adrian A. LUND, Linda LUTFIYYA, Thomas M. MALVAR, Donald E. NELSON, Monnanda S. RAJANI, Dhanalakshmi RAMACHANDRA, Thomas G. RUFF, Sara SALVADOR, S. SANGEETHA, Char SHOBHA, Jeffrey M. STAUB, Virginia URSIN, Tyamagondlu V. VENKATESH, Kammaradi R. VIDYA, Xiaoyun WU, Sean YANG, Jianmin ZHAO
  • Patent number: 9708620
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: July 18, 2017
    Assignee: Monsanto Technology LLC
    Inventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
  • Publication number: 20170029844
    Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
    Type: Application
    Filed: July 22, 2016
    Publication date: February 2, 2017
    Inventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
  • Patent number: 9212370
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: December 15, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
  • Patent number: 9119408
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: September 1, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Publication number: 20150191728
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Application
    Filed: March 20, 2015
    Publication date: July 9, 2015
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • Publication number: 20150184179
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Application
    Filed: December 24, 2014
    Publication date: July 2, 2015
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar