Patents by Inventor Thomas M. Malvar
Thomas M. Malvar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240117374Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.Type: ApplicationFiled: October 30, 2023Publication date: April 11, 2024Inventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
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Patent number: 11840700Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.Type: GrantFiled: July 22, 2016Date of Patent: December 12, 2023Assignee: Monsanto Technology LLCInventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
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Publication number: 20230348543Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: ApplicationFiled: May 17, 2023Publication date: November 2, 2023Inventors: James A. BAUM, David J. BOWEN, Catherine A. CHAY, David J. CHI, William P. CLINTON, Crystal L. DART, Leigh ENGLISH, Stanislaw FLASINSKI, Victor M. GUZOV, Kevin A. JARRELL, Uma R. KESANAPALLI, Thomas M. MALVAR, Robert M. MCCARROLL, Jason S. MILLIGAN, Jay P. MORGENSTERN, Deborah G. RUCKER, Sara A. SALVADOR, Temple F. SMITH, Carlos E. SOTO, Collin M. STULTZ, Brian M. TURCZYK, Ty T. VAUGHN, Moritz W.F. VON RECHENBERG
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Patent number: 11702455Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: GrantFiled: June 5, 2020Date of Patent: July 18, 2023Assignee: Monsanto Technology LLCInventors: James A. Baum, David J. Bowen, Catherine A. Chay, David J. Chi, William P. Clinton, Crystal L. Dart, Leigh English, Stanislaw Flasinski, Victor M. Guzov, Kevin A. Jarrell, Uma R. Kesanapalli, Thomas M. Malvar, Robert M. McCarroll, Jason S. Milligan, Jay P. Morgenstern, Deborah G. Rucker, Sara A. Salvador, Temple F. Smith, Carlos E. Soto, Collin M. Stultz, Brian M. Turczyk, Ty T. Vaughn, Moritz W. F. Von Rechenberg
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Publication number: 20200369733Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: ApplicationFiled: June 5, 2020Publication date: November 26, 2020Inventors: James A. BAUM, David J. BOWEN, Catherine A. CHAY, David J. CHI, William P. CLINTON, Crystal L. DART, Leigh ENGLISH, Stanislaw FLASINSKI, Victor M. GUZOV, Kevin A. JARRELL, Uma R. KESANAPALLI, Thomas M. MALVAR, Robert M. MCCARROLL, Jason S. MILLIGAN, Jay P. MORGENSTERN, Deborah G. RUCKER, Sara A. SALVADOR, Temple F. SMITH, Carlos E. SOTO, Collin M. STULTZ, Brian M. TURCZYK, Ty T. VAUGHN, Moritz W.F.F. VON RECHENBERG
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Patent number: 10793869Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: GrantFiled: June 29, 2017Date of Patent: October 6, 2020Assignee: MONSANTO TECHNOLOGY LLCInventors: Edwards M. Allen, Larry A Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
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Patent number: 10772276Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.Type: GrantFiled: March 9, 2018Date of Patent: September 15, 2020Assignee: Monsanto Technology LLCInventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
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Patent number: 10703782Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.Type: GrantFiled: January 11, 2018Date of Patent: July 7, 2020Assignee: Monsanto Technology LLCInventors: James A. Baum, David J. Bowen, Catherine A. Chay, David J. Chi, William P. Clinton, Crystal L. Dart, Leigh English, Stanislaw Flasinski, Victor M. Guzov, Kevin A. Jarrell, Uma R. Kesanapalli, Thomas M. Malvar, Robert M. McCarroll, Jason S. Milligan, Jay P. Morgenstern, Deborah G. Rucker, Sara A. Salvador, Temple F. Smith, Carlos E. Soto, Collin M. Stultz, Brian M. Turczyk, Ty T. Vaughn, Moritz W. F. Von Rechenberg
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Publication number: 20180263205Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.Type: ApplicationFiled: March 9, 2018Publication date: September 20, 2018Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
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Patent number: 9976139Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.Type: GrantFiled: March 20, 2015Date of Patent: May 22, 2018Assignee: Monsanto Technology LLCInventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
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Patent number: 9913487Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.Type: GrantFiled: June 10, 2013Date of Patent: March 13, 2018Assignee: Monsanto Technology LLCInventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
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Publication number: 20180007856Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.Type: ApplicationFiled: June 10, 2013Publication date: January 11, 2018Applicant: Monsanto Technology LLCInventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
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Publication number: 20180002713Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: June 29, 2017Publication date: January 4, 2018Inventors: Edwards M. ALLEN, Larry A. GILBERTSON, Sara E. HEISEL, Shihshieh HUANG, Elysia K. KRIEGER, Thomas M. MALVAR
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Publication number: 20170233755Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: April 28, 2017Publication date: August 17, 2017Applicant: Monsanto Technology LLCInventors: Mark Scott ABAD, Pranesh BADAMI, Amarjit BASRA, Erin BELL, Christopher P. BONIN, Paolo CASTIGLIONI, R. Eric CERNY, Jaishree M. CHITTOOR, Paul CHOMET, Todd DEZWAAN, Stephen DUFF, Michael D. EDGERTON, Barry S. GOLDMAN, Balasulojini KARUNANANDAA, Kempagangaiah KRISHNAMURTHY, Ping LI, Adrian A. LUND, Linda LUTFIYYA, Thomas M. MALVAR, Donald E. NELSON, Monnanda S. RAJANI, Dhanalakshmi RAMACHANDRA, Thomas G. RUFF, Sara SALVADOR, S. SANGEETHA, Char SHOBHA, Jeffrey M. STAUB, Virginia URSIN, Tyamagondlu V. VENKATESH, Kammaradi R. VIDYA, Xiaoyun WU, Sean YANG, Jianmin ZHAO
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Patent number: 9708620Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: GrantFiled: December 24, 2014Date of Patent: July 18, 2017Assignee: Monsanto Technology LLCInventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
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Publication number: 20170029844Abstract: Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.Type: ApplicationFiled: July 22, 2016Publication date: February 2, 2017Inventors: Timothy K. Ball, Artem G. Evdokimov, Larry A. Gilbertson, Victor M. Guzov, Jeffrey A. Haas, Qing Huai, Sergey Ivashuta, Melissa M. Kemp, Yifei Kong, Thomas M. Malvar, Byron V. Olsen, Parthasarathy Ramaseshadri, Brian E. Weiner
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Patent number: 9212370Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: GrantFiled: March 18, 2010Date of Patent: December 15, 2015Assignee: Monsanto Technology LLCInventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar
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Patent number: 9119408Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.Type: GrantFiled: June 10, 2013Date of Patent: September 1, 2015Assignee: Monsanto Technology LLCInventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
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Publication number: 20150191728Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.Type: ApplicationFiled: March 20, 2015Publication date: July 9, 2015Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
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Publication number: 20150184179Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.Type: ApplicationFiled: December 24, 2014Publication date: July 2, 2015Applicant: MONSANTO TECHNOLOGY LLCInventors: Edwards M. Allen, Larry A. Gilbertson, Sara E. Heisel, Shihshieh Huang, Elysia K. Krieger, Thomas M. Malvar