Patents by Inventor Thomas M. McNerney

Thomas M. McNerney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLOCCULATION METHOD
    Publication number: 20160297850
    Abstract: The present invention relates to a method for harvesting recombinant proteins from mammalian cell culture fluid. The method makes use of cationic polymers, non-ionic polymers and non-ionic surfactants.
    Type: Application
    Filed: June 20, 2016
    Publication date: October 13, 2016
    Inventors: Thomas M. McNerney, Krista PETTY, Anne C. THOMAS, Xiaoyang ZHAO
  • FLOCCULATION METHOD
    Publication number: 20150004646
    Abstract: The present invention relates to a method for harvesting recombinant proteins from mammalian cell culture fluid. The method makes use of cationic polymers, non-ionic polymers and non-ionic surfactants.
    Type: Application
    Filed: December 14, 2012
    Publication date: January 1, 2015
    Inventors: Thomas M. McNerney, Krista Petty, Anne C Thomas, Xiaoyang Zhao
  • Control of ph transitions during chromatography
    Patent number: 7101982
    Abstract: The invention provides methods of controlling pH variations during chromatography. In particular embodiments, the invention includes equilibrating and eluting proteins from chromatography resins have a solid phase that possesses a charged functional group on its backbone under controlled conditions of osmolarity and pH. The invention is particularly useful in the purification of proteins that are sensitive to pH transitions such as, for example, the IL-1 Receptor type II protein.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: September 5, 2006
    Assignee: Immunex Corporation
    Inventors: Sanchayita Ghose, Thomas M. McNerney
  • Control of pH transitions during chromatography
    Publication number: 20030004094
    Abstract: The invention provides methods of controlling pH variations during chromatography. In particular embodiments, the invention includes equilibrating and eluting proteins from chromatography resins have a solid phase that possesses a charged functional group on its backbone under controlled conditions of osmolarity and pH. The invention is particularly useful in the purification of proteins that are sensitive to pH transitions such as, for example, the IL-1 Receptor type II protein.
    Type: Application
    Filed: March 29, 2002
    Publication date: January 2, 2003
    Inventors: Sanchayita Ghose, Thomas M. McNerney