Patents by Inventor Thomas M. Schmidt

Thomas M. Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODULATING GUT MICROBIOMES
    Publication number: 20250295712
    Abstract: Provided herein are compositions and methods for modulating gut microbiomes to treat or prevent diseases. For example, provided herein are microorganisms or components thereof (e.g., proteins involved in associating dietary fibers, such as resistant starch, with beneficial gut microorganisms) that find use treating diseases having an inflammatory component, such as Graft versus Host Disease and cancer. Prebiotic, probiotic, and synbiotic compositions are also provided. In some embodiments, the bacteria are those that naturally express pili that attach to RS granules. In other embodiments, the bacterial are engineered to express or present pili or pilus proteins (e.g., tip pilin) that attach to RS granules.
    Type: Application
    Filed: February 9, 2023
    Publication date: September 25, 2025
    Inventor: Thomas M. Schmidt
  • Compositions and methods for increasing butyrate production
    Patent number: 11931386
    Abstract: Provided herein are compositions and methods for increasing butyrate production in a subject. In particular, provided herein are compositions, probiotic compositions, and combinations thereof that promote butyrate production in a subject.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: March 19, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Thomas M. Schmidt, Nielson Baxter, Kwi Kim, Alexander Schmidt, Arvind Venkataraman, Clive Waldron
  • COMPOSITIONS AND METHODS FOR INCREASING BUTYRATE PRODUCTION
    Publication number: 20210077546
    Abstract: Provided herein are compositions and methods for increasing butyrate production in a subject. In particular, provided herein are compositions, probiotic compositions, and combinations thereof that promote butyrate production in a subject.
    Type: Application
    Filed: August 29, 2018
    Publication date: March 18, 2021
    Inventors: Thomas M. SCHMIDT, Nielson BAXTER, Kwi KIM, Alexander SCHMIDT, Arvind VENKATARAMAN, Clive WALDRON
  • Endogenous ketogulonigenium plasmid
    Patent number: 6503748
    Abstract: The present invention relates, in general, to an isolated or purified nucleic acid molecule comprising a nucleotide sequence of an endogenous plasmid contained in NRRL Deposit No. B-30035.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: January 7, 2003
    Assignees: Archer-Daniels-Midland Company, Board of Trustees of Michigan State University
    Inventors: Thomas M. Schmidt, Steven F. Stoddard
  • Endogenous ketogulonigenium plasmid
    Publication number: 20020064871
    Abstract: The present invention relates, in general, to an isolated or purified nucleic acid molecule comprising a nucleotide sequence of an endogenous plasmid contained in NRRL Deposit No. B-30035.
    Type: Application
    Filed: April 5, 2001
    Publication date: May 30, 2002
    Inventors: Thomas M. Schmidt, Steven F. Stoddard