Patents by Inventor Thomas M. Setcavage

Thomas M. Setcavage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inactivating viruses
    Publication number: 20020015937
    Abstract: The present invention is for improved methods of inactivating viruses in a sample by exposing the sample to a combination of pressure treatment and exposure to an inactivating agent. The sample can be repeatedly cycled between relatively high and low pressures and the inactivating agent is selected from ethyleneimine, ethyleneimine oligomers, psoralens, DNase and RNase.
    Type: Application
    Filed: January 29, 2001
    Publication date: February 7, 2002
    Inventors: Thomas M. Setcavage, Kenneth Denich
  • Agglutination reaction and separation vessel
    Patent number: 6187583
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: May 28, 1998
    Date of Patent: February 13, 2001
    Inventors: Walter Milchanoski, Milan Jorik, Kathleen J. Reis, Diane E. Bechtold, Linda Davis, Thomas M. Setcavage
  • Foil sealed cassette for agglutination reactions and liner therefor
    Patent number: 5780248
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: February 2, 1996
    Date of Patent: July 14, 1998
    Assignee: Ortho Diagnostic Systems, Inc.
    Inventors: Walter Milchanoski, Milan Jorik, Kathleen J. Reis, Diane E. Bechtold, Linda Davis, Thomas M. Setcavage, Donald M. Davies
  • Column agglutination assay and device using biphasic centrifugation
    Patent number: 5650068
    Abstract: The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells. The device of the invention further comprises a chamber the transverse cross-sectional shape thereof being an ellipse, or preferably a flattened ellipse with two sides parallel to the longitudinal axis.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: July 22, 1997
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Rosemary K. Chachowski, Thomas M. Setcavage, Kathleen J. Reis
  • Column agglutination assay and device using biphasic centrifugation
    Patent number: 5552064
    Abstract: The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: September 3, 1996
    Assignee: Ortho Diagnostic Systems, Inc.
    Inventors: Rosemary K. Chachowski, Thomas M. Setcavage, Kathleen J. Reis
  • Agglutination reaction and separation vessel
    Patent number: 5491067
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: July 16, 1993
    Date of Patent: February 13, 1996
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Thomas M. Setcavage, Kathleen J. Reis, Donald M. Davies, Edward J. Mazur