Patents by Inventor Thomas M. Valentine

Thomas M. Valentine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117300
    Abstract: Bacterial cultures are provided that comprise a modified Pseudomonas aeruginosa bacterium missing or deficient in two or more virulence factors. The two or more virulence factors can be selected from exotoxin A, hemolytic phospholipase C, phenazine-specific methyltransferase, alpha-1,3-rhamnosyltransferase, and 3-phosphoshikimate 1-carboxyvinyltransferase. Certain of the modified Pseudomonas aeruginosa bacteria are also missing or deficient in one or more alginate acetylation enzymes including the alginate O-acetyltransferases AlgI, AlgJ, AlgF, AlgX, and/or the C5-mannuronan epimerase AlgG. Methods of producing alginate are also provided along with compositions comprising alginate produced by the modified Pseudomonas aeruginosa bacteria.
    Type: Application
    Filed: November 30, 2023
    Publication date: April 11, 2024
    Inventors: Hongwei D. Yu, Meagan E. Valentine, Richard M. Niles, Thomas Ryan Withers, Brandon D. Kirby
  • Patent number: 4471026
    Abstract: The invention relates to the use of ternary alloys in brazing ceramics.Brazing is a process of limited usefulness in the fabrication of ceramic components because of the inability of many alloys to wet industrially important ceramics. A possible solution is the metallizing of ceramics but this has technical and economic disadvantages. Alloys are known which wet ceramics but they do not necessarily give good bond strength. The following alloys have now been devised which both wet ceramics and give good bond strength, e.g., greater than 40 MNm.sup.-2 at room temperature, with unmetallized ceramics. The alloys are:Cu: 16 to 28 Ti: 6.5 to 14 SnCu: 15 to 25 Ti: 10 to 25 AuCu: 15 to 50 Ti: 3 to 10 AgCu: 25 to 35 Ti: 3 to 8 Inwherein the compositions are in atom percent.
    Type: Grant
    Filed: November 3, 1982
    Date of Patent: September 11, 1984
    Assignee: United Kingdom Atomic Energy Authority
    Inventors: Michael G. Nicholas, Thomas M. Valentine