Patents by Inventor Thomas MacAllister

Thomas MacAllister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloning, overexpression and therapeutic use of bioactive histidine ammonia lyase
    Patent number: 6939541
    Abstract: Histidine ammonia lyase (HAL) isolated from Corynebacteriaceae can decrease serum histidine levels, induce accumulation of urocanic acid, and is not inhibited by L-histidinol. As a result, histidine ammonia lyases similar to the one isolated from Corynebacteriaceae are uniquely suitable for combination therapy with L-histidinol to treat histidine- and/or histamine-dependent pathologies, for example, infectious viruses, such as human Respiratory Syncytial Virus (RSV), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV), as well as cancers.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: September 6, 2005
    Assignee: University of South Carolina
    Inventors: Joseph Roberts, Natarajan Sethuraman, Thomas MacAllister
  • Cloning, overexpression and therapeutic use of bioactive histidine ammonia lyase
    Publication number: 20020052038
    Abstract: Histidine ammonia lyase (HAL) isolated from Corynebacteriaceae can decrease serum histidine levels, induce accumulation of urocanic acid, and is not inhibited by L-histidinol. As a result, histidine ammonia lyases similar to the one isolated from Corynebacteriaceae are uniquely suitable for combination therapy with L-histidinol to treat histidine- and/or histamine-dependent pathologies, for example, infectious viruses, such as human Respiratory Syncytial Virus (RSV), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV), as well as cancers.
    Type: Application
    Filed: April 13, 2001
    Publication date: May 2, 2002
    Inventors: Joseph Roberts, Natarajan Sethuraman, Thomas MacAllister