Patents by Inventor Thomas Mallegol

Thomas Mallegol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nonlinear optical detection of fast cellular electrical activity
    Publication number: 20050259249
    Abstract: The present invention is directed to various methods involving nonlinear microscopy and dyes that are sensitive to fast cellular membrane potential signals and capable of generating nonlinear optical signals. The present invention includes methods of producing high spatiotemporal resolution images of electrical activity in cellular tissue, as well as methods of detecting and investigating disease within a particular cellular tissue of a living organism. The present invention further relates to methods of detecting membrane potential signal changes in a neuron or a part of a neuron, as well as in a population of cells.
    Type: Application
    Filed: January 27, 2005
    Publication date: November 24, 2005
    Inventors: Daniel Dombeck, Watt Webb, Mireille Blanchard-Desce, Olivier Mongin, Thomas Mallegol