Abstract: Disclosed herein are methods and pressure vessels for solid-state microcellular processing of thermoplastic rolls and sheets. In one embodiment, the present invention is directed to a method for making a gas impregnated interleaved roll, which method comprises: providing a pressure vessel having an internal pressure chamber and a rotatable shaft horizontally positioned within the pressure chamber; placing an interleaved roll about the rotatable shaft and within the pressure chamber, wherein the interleaved roll is made from a thermoplastic material sheet interleaved together with a gas-channeling material sheet; pressurizing the pressure chamber to a selected pressure; rotating the rotatable shaft having the interleaved roll thereabouts (thereby rotating the interleaved roll) while under pressure for a selected period of time; and depressurizing the internal chamber to yield the gas impregnated interleaved roll.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: An elevator door lock assembly (30) includes a sensor device (40) for providing an indication of a properly locked door. A plurality of proximity sensor elements (42, 44) interact with activating elements (52, 54) when the door lock assembly (30) is properly locked. In disclosed examples, a specific geometric pattern of the sensor elements (42, 44) and the activating elements (52, 54) provides redundancy and tampering protection. In a disclosed example, an output from the sensor device (40) provides an indication of a condition of the door lock and a building level location of a plurality of sensor devices.

Abstract: Disclosed herein are methods and pressure vessels for solid-state microcellular processing of thermoplastic rolls and sheets. In one embodiment, the present invention is directed to a method for making a gas impregnated interleaved roll, which method comprises: providing a pressure vessel having an internal pressure chamber and a rotatable shaft horizontally positioned within the pressure chamber; placing an interleaved roll about the rotatable shaft and within the pressure chamber, wherein the interleaved roll is made from a thermoplastic material sheet interleaved together with a gas-channeling material sheet; pressurizing the pressure chamber to a selected pressure; rotating the rotatable shaft having the interleaved roll thereabouts (thereby rotating the interleaved roll) while under pressure for a selected period of time; and depressurizing the internal chamber to yield the gas impregnated interleaved roll.

Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

Abstract: An elevator door lock assembly (30) includes a sensor device (40) for providing an indication of a properly locked door. A plurality of proximity sensor elements (42, 44) interact with activating elements (52, 54) when the door lock assembly (30) is properly locked. In disclosed examples, a specific geometric pattern of the sensor elements (42, 44) and the activating elements (52, 54) provides redundancy and tampering protection. In a disclosed example, an output from the sensor device (40) provides an indication of a condition of the door lock and a building level location of a plurality of sensor devices.

Abstract: An elevator door lock includes a locking member (40) that moves into an unlocked position responsive to contact with at least one door coupler member (32, 34). In disclosed examples, the locking member (40) comprises an arm that is pivotally supported by one of the door coupler members (34). The other coupler member (32) contacts a contact portion (42) on the locking member (40) to move the locking member into an unlocked position as the first coupler member (32) moves toward the second coupler member (34). In a disclosed example, a magnetic coupling between the coupler members maintains the locking member (40) in an unlocked position.

Abstract: An elevator door assembly (20) includes a single vane member (32) associated with a hoistway door (26). A magnetic device (36) on a car door (24) establishes a magnetic coupling with the vane member (32) to cause the hoistway door (26) to move with the car door (24) in at least two opposite directions. In a disclosed embodiment, a control (38) selectively powers the magnetic device (36), which comprises an electromagnet.

Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

Abstract: Biocompatible intraocular drug delivery systems include a anti-angiogenic therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or microparticles, and combinations thereof. The therapeutic agent is released in a biologically active form, for example, the therapeutic agent may retain its three dimensional structure when released into an eye of a patient, or the therapeutic agent may have an altered three dimensional structure but retain its therapeutic activity. The therapeutic agent may be selected from the group consisting of anti-angiogenesis peptides, hormones and nucleic acid agents. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy among others.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: There is provided a display device for a vehicle having a seat. The display device includes an assembly housing adapted to mount at a rear portion of the seat. A receiver is adapted to receive at least one of video and audio signals from at least one external input device. At least one wireless transmitter operatively coupled to the receiver, is adapted to wirelessly transmit the audio signals to at least one wireless headphone set. The display device is adapted to reproduce the video signals. In some embodiments of the invention, the at least one wireless transmitter is adapted to transmit the audio signals based on Code-Division Multiple Access (CDMA) technology.

Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.