Patents by Inventor Thomas Malvar

Thomas Malvar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide compositions encoding broad spectrum delta-endotoxins
    Publication number: 20020064865
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Application
    Filed: June 4, 2001
    Publication date: May 30, 2002
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Polynucleotide compositions encoding Cry1Ac/Cry1F chimeric O-endotoxins
    Patent number: 6326169
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: December 4, 2001
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Broad-spectrum insect resistant transgenic plants
    Patent number: 6281016
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and tansgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: August 28, 2001
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Polynucleotide compositions encoding broad-spectrum &dgr;-endotoxins
    Patent number: 6242241
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: June 5, 2001
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Chimeric bacillus thuringiensis-endotoxins and host cells expressing same
    Patent number: 6221649
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: April 24, 2001
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Hybrid Bacillus thuringiensis .delta.-endotoxins with novel broad-spectrum insecticidal activity
    Patent number: 6156573
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: December 5, 2000
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Broad-spectrum .delta.-endotoxins
    Patent number: 6110464
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: August 29, 2000
    Assignee: Monsanto Company
    Inventors: Thomas Malvar, Amy Jelen Gilmer
  • Hybrid Bacillus thuringiensis .delta.-endotoxins with novel broad-spectrum insecticidal activity
    Patent number: 6017534
    Abstract: Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells. Transformed host cells and transgenic plants expressing the modified endotoxin are also aspects of the invention.
    Type: Grant
    Filed: November 20, 1996
    Date of Patent: January 25, 2000
    Assignee: Ecogen, Inc.
    Inventors: Thomas Malvar, Amy Jelen Gilmer