Patents by Inventor Thomas Mander

Thomas Mander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR DETECTING ENZYME ACTIVITY IN AN IMMUNOASSAY
    Publication number: 20100021939
    Abstract: The invention relates to a process for detecting enzyme activity in an immunoassay comprising the following steps: a) providing a protein, a peptide, or a derivative thereof comprising the sequence motif -Z-X-Y- or -Y-X-Z- wherein Z=an amino acid to be modified by the enzyme, X=a sequence of amino acids, preferably between 0 and 1000 amino acids which may be the same or different, Y=a discrimination enhancer for the binding to an antibody, as a substrate for the enzyme; b) incubating the protein, peptide, or derivative thereof with the enzyme to form a modified protein, peptide, or derivative thereof; c) adding an antibody discriminating the modified Z from the unmodified Z position of said protein, peptide, or derivative thereof, said discrimination being mediated by the presence of the affinity enhancer; and d) detecting the enzyme activity.
    Type: Application
    Filed: July 20, 2009
    Publication date: January 28, 2010
    Inventors: Joachim Krämer, Christiane Peiker, Karsten Henco, Thomas Mander
  • Process for detecting serine/threonine kinase activity
    Patent number: 7049080
    Abstract: The present invention describes a process for detecting threonine or serine kinase activity in an immunoassay using a pre-phosphorylated substrate.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: May 23, 2006
    Inventors: Joachim Kramer, Thomas Mander, Richard Bethell, Neil Benson, Helen Boyd, Pam Greengrass, Ross Kinloch
  • Process for detecting enzyme activity in an immunoassay
    Publication number: 20030235873
    Abstract: The invention relates to a process for detecting enzyme activity in an immunoassay comprising the following steps:
    Type: Application
    Filed: July 8, 2003
    Publication date: December 25, 2003
    Inventors: Joachim Krmer, Thomas Mander, Christiane Peiker, Karsten Henco
  • Process for detecting serine/threonine kinase activity
    Publication number: 20020086336
    Abstract: The present invention describes a process for detecting threonine or serine kinase activity in an immunoassay using a pre-phosphorylated substrate.
    Type: Application
    Filed: August 7, 2001
    Publication date: July 4, 2002
    Inventors: Joachim Kramer, Thomas Mander, Richard Bethell, Neil Benson, Helen Boyd, Pam Greengrass, Ross Kinloch