Patents by Inventor Thomas Manuel Keller

Thomas Manuel Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210229098
    Abstract: A medical system for determining an analyte quantity in a blood sample via a cartridge that spins around a rotational axis. The cartridge may include: a separation chamber that separates blood plasma from the sample; a processing chamber containing a reagent with a specific binding partner which binds to the analyte to form an analyte specific binding partner complex; a first valve structure connecting the separation chamber to the processing chamber; a measurement structure to measure the quantity of the analyte, wherein the measurement structure includes a chromatographic membrane with an immobilized binding partner for direct or indirect binding of the analyte or the analyte specific binding partner complex, and an absorbent structure that is nearer to the axis than the membrane; a second valve structure connecting the processing chamber to the measurement structure; and a fluid chamber filled with a washing buffer and fluidically connected to the measurement structure.
    Type: Application
    Filed: April 13, 2021
    Publication date: July 29, 2021
    Inventors: Christoph Boehm, Thorsten Brueckner, Thomas Fischer, Eloisa Lopez-Calle, Sascha Lutz, Josef Roedl, Juergen Spinke, Pamela Espindola, Thomas Manuel Keller, Thomas Dolbinow, Sabrina Adler, Erik Beiersdorf, Domenik Wensorra
  • Patent number: 11000848
    Abstract: A medical system for determining an analyte quantity in a blood sample via a cartridge that spins around a rotational axis. The cartridge may include: a separation chamber that separates blood plasma from the sample; a processing chamber containing a reagent with a specific binding partner which binds to the analyte to form an analyte specific binding partner complex; a first valve structure connecting the separation chamber to the processing chamber; a measurement structure to measure the quantity of the analyte, wherein the measurement structure includes a chromatographic membrane with an immobilized binding partner for direct or indirect binding of the analyte or the analyte specific binding partner complex, and an absorbent structure that is nearer to the axis than the membrane; a second valve structure connecting the processing chamber to the measurement structure; and a fluid chamber filled with a washing buffer and fluidically connected to the measurement structure.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: May 11, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christoph Boehm, Thomas Dolbinow, Sabrina Adler, Erik Beiersdorf, Domenik Wensorra, Thorsten Brueckner, Thomas Fischer, Eloisa Lopez-Calle, Sascha Lutz, Josef Roedl, Juergen Spinke, Pamela Espindola, Thomas Manuel Keller
  • Publication number: 20180264471
    Abstract: A medical system for determining an analyte quantity in a blood sample via a cartridge that spins around a rotational axis. The cartridge may include: a separation chamber that separates blood plasma from the sample; a processing chamber containing a reagent with a specific binding partner which binds to the analyte to form an analyte specific binding partner complex; a first valve structure connecting the separation chamber to the processing chamber; a measurement structure to measure the quantity of the analyte, wherein the measurement structure includes a chromatographic membrane with an immobilized binding partner for direct or indirect binding of the analyte or the analyte specific binding partner complex, and an absorbent structure that is nearer to the axis than the membrane; a second valve structure connecting the processing chamber to the measurement structure; and a fluid chamber filled with a washing buffer and fluidically connected to the measurement structure.
    Type: Application
    Filed: May 17, 2018
    Publication date: September 20, 2018
    Inventors: Christoph Boehm, Thorsten Brueckner, Thomas Fischer, Eloisa Lopez-Calle, Sascha Lutz, Josef Roedl, Juergen Spinke, Pamela Espindola, Thomas Manuel Keller, Thomas Dolbinow, Sabrina Adler, Erik Beiersdorf, Domenik Wensorra