Abstract: The present invention relates to methods for treating atopic dermatitis in a subject using an interleukin-13 (IL-13) binding protein, such as an anti-IL-13 antibody or an IL-13-binding fragment thereof.

Abstract: The present invention relates to methods for treating atopic dermatitis in a subject using an interleukin-13 (IL-13) binding protein, such as an anti-IL-13 antibody (e.g. Tralokinumab) or an IL-13-binding fragment thereof.

Abstract: The invention relates to a fastening mechanism (1) for shoes, articles of clothing, tents, rucksacks etc. with a lace or tape-like tying element (2) which is inserted into a guiding tab (9) designed as a hook or eye, which at least in an end region (15) which is opposite a fastening tab (4) connected to the guiding tab (9), has a base web (16), which spaces apart the facing inner surfaces (18) of two arms (10) of the guiding tab (9) at a distance (19), whereby the inner surfaces (18) with the base web (16) form a housing chamber (20) for the tying element (2), in which a reversing element (21) for the tying element (2) is arranged, whereby the reversing element (21) is arranged at a distance (24) from the base web (16) in the direction of the fastening tab (4) and has a height (27) which corresponds at least to the distance (19).

Abstract: The invention relates to a fastening element (1) with a cylindrical casing (2) comprising an internal thread (20), which at one of its outside ends has at least one support element (4) projecting over the casing (2) in a plane perpendicular to the longitudinal middle axis (3), and at an end region (23) of the casing (2) opposite the support element (4) at least two expanding elements (29) which project over the latter in longitudinal direction and are deformable in radial direction are arranged, and the support element (4) and the casing (2) with the expanding elements (29) are made of a one-piece metal component, whereby at least one securing extension (7) is arranged on the support element (4) and the expanding elements (29) converge in the direction of a length and outside faces (28) of the expanding elements (29) opposite the support element (4) are arranged at an angle to one another.

Abstract: The invention relates to a jamming device (1) for a cord or tape fastener (30), such as e.g. shoelaces (31), for shoes, jackets, trousers and other articles of clothing, comprising a ring lug (3) for looping the fastening means (30) and a rivet strap (2) which forms a hinge bearing (14) for the ring lug (3) and which is joined to the article of clothing by means of at least one fixing element, such as for example a rivet, stitching or gluing, the rivet strap (2) having a jamming cleat (43) joined to the rivet strap and provided with an end face (35) which is surrounded by the ring lug (30) when the latter is in a position more or less parallel with a contact surface (11) in a jamming zone (29) which is made up of jamming surfaces (36) formed by the end face (35) and an inner surface of the ring lug (3) facing the end face (35), the jamming surfaces (36) being separated from each other by a gap (38) in the jamming zone (29).