Abstract: Illumination devices for directing light on tissue to induce one or more biological effects and more particularly phototherapeutic illumination devices with modular structures are disclosed. Modular structures are disclosed that provide the ability to have various changeable attributes for illumination devices based on intended treatment protocols. Modular structures may include tokens, switches, handles, rechargeable power structures, control modules, illumination modules, optics, light guides, and/or light guide positioners, among others.

Abstract: The invention relates to substituted heterocycles of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.

Abstract: Provided herein are compounds of Formula (I), a compound selected from any of the compounds in Table 1, Table 2, Table 3, or a pharmaceutically acceptable salt or deuterated form thereof, wherein R1, R2, R3 and R4 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of formula (I), or a compound selected from any of the compounds in Table 1, Table 2, Table 3, or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of formula (I) or pharmaceutically acceptable salt or deuterated form thereof, e.g., in treating 5-HT2A receptor associated diseases or disorders.

Abstract: Provided herein are compounds of Formula (I), Formula (II), Formula (III), a compound selected from any of the compounds in Table 1, Table 2, Table 3, Table 4 or a pharmaceutically acceptable salt or deuterated form thereof, wherein R1, R2, R3, R4, RD, RG, p and q are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of formula (I), or a compound selected from any of the compounds in Table 1, Table 2, Table 3, Table 4 or pharmaceutically acceptable salt or deuterated form thereof, and methods of using a compound of formula (I), Formula (II), Formula (III), or pharmaceutically acceptable salt or deuterated form thereof, e.g., in treating 5-HT2A receptor associated diseases or disorders.

Abstract: The present disclosure is directed to methods and techniques for gob-pressing a glass part of challenging geometries, such as large surfaces with thin thickness as well as features positioned far from a centroid of the part.

Abstract: A glass facer for a constructions board includes a first non-woven layer of coarse fibers and a second non-woven layer of coarse fibers and microfibers. The glass facer also includes a binder that simultaneously binds or adheres the coarse fibers of the first non-woven layer together, the coarse fibers and the microfibers of the second non-woven layer together, and the first non-woven layer to the second non-woven layer. The first non-woven layer has a porosity and air permeability that enables the first non-woven layer to absorb a material of the construction board when the glass facer is positioned atop the construction board during manufacture of the construction board. The second non-woven layer is configured to block the material of the construction board from passing through the glass facer to an exterior surface of the second non-woven layer so that the material is not externally visible.

Abstract: Disclosed herein is computer-implemented method for processing at least one image of a location of a body of a subject. The method may comprise obtaining the at least one image, and using a trained algorithm to classify the at least one image or a derivative thereof to a category among a plurality of categories comprising a first category and a second category. The classifying may comprise applying a image processing algorithm. The method may comprise, based at least in part on the classifying, designating the at least one image or derivative thereof as having a first or second priority (e.g., lower priority or urgency than the first priority) for radiological assessment if the at least one image is classified to the first or second category, respectively. The method may comprise generating an electronic assessment of the subject, such as a negative report indicative of the subject not having a health condition.

Abstract: Generally, described herein are computer-implemented systems and methods for self-guided education in various aspects of health care. The described systems and methods effect behavior change through a functional relationship between the content of educational case packages comprising a plurality of displays, each of which has one or more completion conditions which must be completed by the user in accordance with a health care procedure to be practiced. The performance of the case by the user habituates behavior change through practice of a health care procedure.

Abstract: A brace that includes a body and a sensor device disposed in the body, where the sensor device includes a sensor that is configured to measure at least one parameter associated with a position of the housing. The brace also includes a controller communicably coupled to the sensor device. The controller can be configured to receive a plurality of measurements of the at least one parameter taken by the sensor device. The controller can also be configured to evaluate each measurement of the plurality of measurements.

Abstract: The disclosure herein describes providing responses to natural language queries associated with transcripts at least by searching multiple indexes. A transcript associated with a communication among a plurality of speakers is obtained, wherein sets of artifact sections are identified in the transcript. A set of section indexes is generated from the transcript based on artifact type definitions. A natural language query associated with the transcript is analyzed using a natural language model and query metadata of the analyzed natural language query is obtained. At least one section index of the set of section indexes is selected based on the obtained query metadata and that selected at least one section index is searched. A response to the natural language query is provided including result data from the searched at least one search index, wherein the result data includes a reference to an artifact section referenced by the searched section index(es).

Abstract: This document relates to employing tongue gestures to control a computing device, and training machine learning models to detect tongue gestures. One example relates to a method or technique that can include receiving one or more motion signals from an inertial sensor. The method or technique can also include detecting a tongue gesture based at least on the one or more motion signals, and outputting the tongue gesture.

Abstract: Generally, described herein are computer-implemented systems and methods for self-guided education in various aspects of health care. The described systems and methods effect behavior change through a functional relationship between the content of educational case packages comprising a plurality of displays, each of which has one or more completion conditions which must be completed by the user in accordance with a health care procedure to be practiced. The performance of the case by the user habituates behavior change through practice of a health care procedure.

Abstract: A laminate sheet article including: a core including an electrical semi-conductor or an electrical conductor; and a continuous glass clad layer on at least four of six sides the core of the sheet article. Also disclosed is an apparatus for making a sheet laminate article as defined herein. Also disclosed is a method of making and using the article.

Abstract: Devices for impinging light on tissue to induce one or more biological effects and more particularly phototherapeutic illumination devices and light guide assemblies with emission-directing structures are disclosed. Emission-directing structures include arrangements of light guides and light guide positioners that may be provided with titled arrangements for directing light emissions toward target tissue. An exemplary light guide may define an optical axis therethrough, and an exemplary light guide positioner may include one or more features that are tilted with respect to the optical axis. Certain tilted features may relate to offset incisor tabs and/or angled biting surfaces that engage within the oral cavity for repeatedly orienting the optical axis in a target direction.

Abstract: Systems, devices, and associated methods are provided for testing and tuning devices under test (e.g., radiofrequency modules). An example system includes a test station including an imaging device, a measurement device, and a robotic arm. The system may include a rotary stage coupled with the robotic arm, measurement probes disposed in the rotary stage and operably coupled with the measurement device, and tuning tips disposed in the rotary stage. The system may include a galvo scanner and laser to remove conductive material. The test station may perform a testing procedure on an RF module where the measurement probes generate testing data indicative of testing parameters. The test station may perform a tuning procedure on the RF module where a tuning tip or the laser modifies the RF module based on the testing parameters. The testing and tuning may be performed by a user, semi-autonomously, or autonomously.

Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity.

Abstract: An imaging optical arrangement serves to image an object illuminated by X-rays. An imaging optics serves to image a transfer field in a field plane into a detection field in a detection plane. A layer of scintillator material is arranged at the transfer field. A stop is arranged in a pupil plane of the imaging optics. The imaging optics has an optical axis. A center of a stop opening of the stop is arranged at a decentering distance with respect to the optical axis. Such imaging optical arrangement ensures a high quality imaging of the object irrespective of a tilt of X-rays entering the transfer field. The imaging optical arrangement is part of a detection assembly further comprising a detection array and an object mount. Such detection assembly is part of a detection system further comprising an X-ray source.

Abstract: Provided is a semi-active seat suspension system that minimizes vibration and energy transmission from a vibration/energy source, such as a motor vehicle, to a seated occupant by means of a spring and computer-controlled damper suspension system. Using a variety of sensors to determine an ideal damping rate at a given point in time, the system adjusts the damping rate in real time to provide the best possible ride to the occupant given the constraints of the system.

Abstract: Systems and methods for building passive and active electronics with diamond-like carbon (DLC) coatings are provided herein. DLC may be layered upon substrates to form various components of electronic devices. Passive components such as resistors, capacitors, and inductors may be built using DLC as a dielectric or as an insulating layer. Active components such as diodes and transistors may be built with the DLC acting substantially like a semiconductor. The amount of sp2and sp3 bonded carbon atoms may be varied to modify the properties of the DLC for various electronic components.

Abstract: Systems and methods reconstruct an image of a subject or object by performing an iterative reconstruction method to produce a plurality of intermediate images and the image of the subject, and transforming at least one selected intermediate image from the plurality of intermediate images using a quasi-projection operator. The quasi-projection operator includes a deep-learning model configured to map the at least one selected intermediate image to at least one regularized intermediate image. In addition, systems and methods for training the deep-learning model using a training data set that includes a plurality of training images and a plurality of corresponding training object images is disclosed.