Abstract: The present disclosure relates to curable silicone elastomer compositions having enhanced adhesive properties with respect to a wide variety of substrates (hereafter referred to as “curable silicone elastomer compositions”). Elastomers made by curing the curable silicone elastomer compositions may be adhered to a wide variety of substrates to form composites comprising the elastomers and the substrates. Processes for adhering the elastomers made by curing the curable silicone elastomer compositions to the substrates are also provided. An adhesion promoter, component (D), is provided to enhance adhesion. Component (D) is a polyorganosiloxane having (i) at least one unsaturated group per molecule selected from alkenyl groups and alkynyl groups and (ii) an anhydride functionality and an aromatic functionality, wherein a carbon of the aromatic functionality is separated from a carbon of a carbonyl group of the anhydride by a carbon chain of from 1 to 3 non-aromatic carbon atoms inclusive.

Abstract: Techniques are described for improving real-time application protection (RTAP) systems (e.g., web application firewalls (WAFs), runtime application self-protection (RASP) systems). In particular, a device within a trusted network may monitor or test the configuration settings of the RTAP systems, network traffic into the RTAP systems, and/or log information from the RTAP systems. For example, the device may detect drift in a configuration for a particular RTAP system by comparing the configuration settings of the RTAP systems to baseline configuration settings and classifying any detected drift as good drift or bad drift. In some examples, the device may maintain the configuration settings or set the configuration settings as the baseline configuration settings when the configurations settings include good drift from the baseline configuration settings. In other examples, the device may set the configuration settings with the bad drift to the baseline configuration settings.

Abstract: Aerial vehicles are assigned to routes within a transportation network based on a state of charge, state of power, and/or state of health for the aerial vehicle. Such aspects can be modeled based on one or more statistical models and/or machine-learned models, among other examples. As another example, an energy budget is used to ensure that the state of charge, state of power, and/or state of health of the aerial vehicle during and/or after traveling the route remains within the energy budget. A payload is assigned to a route and an associated aerial vehicle, thereby generating an itinerary. In examples, the itinerary is validated by the aerial vehicle to ensure that the aerial vehicle is capable of traveling the route with the payload. In examples where the aerial vehicle rejects the itinerary, the itinerary is assigned to another aerial vehicle and a new itinerary is identified for the aerial vehicle.

Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths.

Abstract: Techniques are described for improving real-time application protection (RTAP) systems (e.g., web application firewalls (WAFs), runtime application self-protection (RASP) systems). In particular, a device within a trusted network may monitor or test the configuration settings of the RTAP systems, network traffic into the RTAP systems, and/or log information from the RTAP systems. For example, the device may detect drift in a configuration for a particular RTAP system by comparing the configuration settings of the RTAP systems to baseline configuration settings and classifying any detected drift as good drift or bad drift. In some examples, the device may maintain the configuration settings or set the configuration settings as the baseline configuration settings when the configurations settings include good drift from the baseline configuration settings. In other examples, the device may set the configuration settings with the bad drift to the baseline configuration settings.

Abstract: A speech processing model may be trained using pseudo tokens. Training a speech processing model with pseudo tokens may allow for training with a smaller amount of labeled training data and accordingly lower costs. A set of pseudo tokens may be determined by computing feature vectors from unlabeled training data, clustering the feature vectors, and performing token compression using the clustered feature vectors. A first speech processing model may be trained using unlabeled training data by determining sequences of pseudo tokens corresponding to the unlabeled training data. A second speech processing model may be initialized using the first speech processing model and then trained using labeled training data. The second speech processing model may then be deployed to a speech processing application.

Abstract: Provided herein are methods, techniques and processes for selecting one or more peptides for virus detection (e.g., influenza, SARS-CoV-2) in clinical samples using mass spectrometry. Methods for selecting a combination of peptides to identify one or more disease states in a patient can include: (i) selecting the one or more disease states; (ii) collecting information on proteins associated with the one or more disease states being present within the subject; (ii) in silico digesting individual proteins associated with the one or more disease state to obtain possible workflow peptides; (iv) collecting filtering data associated with the possible workflow peptides; (iv) analyzing the possible workflow peptides for coverage of the one or more disease states and for mass spectrometry detection and resolution; and (iv) selecting the combination of peptides from the possible workflow peptides based on the analyzing step.

Abstract: A computing device including a processor configured to receive source code including a plurality of source code modules. The processor may generate executable code from the source code and assign two or more reload indicators to two or more executable code modules. The processor may execute the executable code. During execution of the executable code, the processor may receive a source code update and generate an executable code update from the source code and the source code update. The processor may apply the executable code update to the executable code to generate updated executable code. The processor may generate a reload ordering of two or more reload operations corresponding to the reload indicators. As specified by the reload ordering, the processor may perform the two or more reload operations at the two or more respective executable code modules. The processor may execute the updated executable code.

Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.

Abstract: Techniques are described for improving real-time application protection (RTAP) systems (e.g., web application firewalls (WAFs), runtime application self-protection (RASP) systems). In particular, a device within a trusted network may be configured to identify risks of the RTAP systems. For example, the device may compare a plurality of attack signatures, from configuration settings of an application protection system to a plurality of defects from a defect data store; determine that at least one configuration setting of the application protection system corresponding to an application does not include protections for at least one defect of the plurality of defects; and in response to determine that the at least one configuration setting of the application protection system does not include protections for the at least one defect, generate an alert corresponding to the at least one defect.

Abstract: A computing device including a processor configured to receive source code including a plurality of source code modules. The processor may generate executable code from the source code and assign two or more reload indicators to two or more executable code modules. The processor may execute the executable code. During execution of the executable code, the processor may receive a source code update and generate an executable code update from the source code and the source code update. The processor may apply the executable code update to the executable code to generate updated executable code. The processor may generate a reload ordering of two or more reload operations corresponding to the reload indicators. As specified by the reload ordering, the processor may perform the two or more reload operations at the two or more respective executable code modules. The processor may execute the updated executable code.

Abstract: An antimicrobial composition containing a synergistic combination of an imidazole antifungal agent and activated creatinine is provided, wherein the imidazole antifungal agent represents in the range of about 0.5 mol % to about 30 mol % of the combination of the antifungal agent and the activated creatinine in the composition. Methods for treating bacterial infections, fungal infections, viral infections, and wounds are also provided, as are other methods of use, including methods for disinfecting inert surfaces, methods for preserving food products, and methods for treating plants. In addition, the invention provides a method for enhancing the antifungal effect of an imidazole antifungal agent as well as a method for enhancing the antibacterial effect of activated creatinine. Compositions and methods involving use of activated 2-amino-imidazol-4-one analogs other than activated creatinine are also provided.

Abstract: A family sized vehicle or car with enhanced entertainment and storage options is disclosed. The vehicle or car of the present invention offers a family functionality, comfort, and style when traveling, especially when traveling long distances with children. The vehicle or car of the present invention includes three rows of seats, having two seats in each of the first and second rows, and four seats connected and arc-positioned in a rear third row. The novel vehicle of the present invention also includes two hidden compartments for the storage of personal items, a relatively deep trunk storage area for luggage, suicide doors, a moonroof and two nine-inch televisions for entertainment.

Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.

Abstract: A computing device including a processor configured to receive source code including a plurality of source code modules. The processor may generate executable code from the source code and assign two or more reload indicators to two or more executable code modules. The processor may execute the executable code. During execution of the executable code, the processor may receive a source code update and generate an executable code update from the source code and the source code update. The processor may apply the executable code update to the executable code to generate updated executable code. The processor may generate a reload ordering of two or more reload operations corresponding to the reload indicators. As specified by the reload ordering, the processor may perform the two or more reload operations at the two or more respective executable code modules. The processor may execute the updated executable code.

Abstract: An antimicrobial composition containing a synergistic combination of an imidazole antifungal agent and activated creatinine is provided, wherein the imidazole antifungal agent represents in the range of about 0.5 mol % to about 30 mol % of the combination of the antifungal agent and the activated creatinine in the composition. Methods for treating bacterial infections, fungal infections, viral infections, and wounds are also provided, as are other methods of use, including methods for disinfecting inert surfaces, methods for preserving food products, and methods for treating plants. In addition, the invention provides a method for enhancing the antifungal effect of an imidazole antifungal agent as well as a method for enhancing the antibacterial effect of activated creatinine. Compositions and methods involving use of activated 2-amino-imidazol-4-one analogs other than activated creatinine are also provided.

Abstract: The disclosure relates to a system for liquid sample introduction into a chromatography system. The system includes a syringe, a first valve in fluid communication with the syringe, a second valve in fluid communication with the sample, a vessel located between, and in fluid communication with, the first and second valves, a third valve in fluid communication with the first valve, the second valve and a chromatography column, and a pump in fluid communication with the third valve and a mobile phase. When the valves are in a first position the syringe draws the sample into the vessel. The mobile phase flows to the chromatography column. When the valves are in a second position, a portion of the mobile phase flows into the vessel, mixing with and pressurizing the sample. When the valves are in a third position, the mixed and pressurized sample flows to the chromatography column.

Abstract: A method for injecting a diluted sample in a chromatography system includes merging a flow of a sample and a flow of a diluent to form a flow of a diluted sample. A dilution ratio of the diluted sample equals a sum of the volumetric flow rates of the sample and the diluent divided by the volumetric flow rate of the sample. The diluted sample is stored in a holding element before injection into a chromatographic system flow. Sample dilution occurs under low pressure relative to the chromatographic flow thereby allowing lower pressure sample and diluent syringes to be used. Other benefits include reduced compressibility and a reduction in leaks due to the lower pressure operation. The method avoids problems associated with manual techniques which can introduce errors due, for example, to loss of sample, sample precipitation and adsorption of sample to vials.

Abstract: The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride. The present invention is also directed to methods for treating inflammation and inducing an immunomodulatory response. In particular, the anti-inflammatory immunomodulators are useful for treating an inflammatory condition or an autoimmune disease.

Abstract: A hardened inductive device and systems and methods for protecting the inductive device from impact is provided. The inductive device is hardened with protective coating and/or an armor steel housing. The hardened inductive device is protected from impact by an object such as a bullet and leakage of dielectric fluid is prevented. Acoustic and vibration sensors are provided to detect the presence and impact, respectively, of an object in relation to the inductive device housing. The measurements of the acoustic and vibration sensors are compared to thresholds for sending alarms to the network control center and initiating shut-down and other sequences to protect the active part. The acoustic sensor results are utilized to determine the location of origin of the projectile.