Patents by Inventor Thomas Michael Willshare

Thomas Michael Willshare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11596944
    Abstract: A microfluidics device has one or more bubble diversion regions. Problems associated with the generation of air bubbles are avoided in a microfluidics device such as a cartridge, for use with a point of care (POC) diagnostics device, the cartridge being able to carry out downstream processing such as polymerase chain reaction (PCR) and/or nucleic acid capture. The bubble diversion region has a lower flow resistance than the flow resistance of an area of interest.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: March 7, 2023
    Assignee: QUANTUMDX GROUP LIMITED
    Inventors: Hojjat Madadi, Thomas Michael Willshare, Jonathan O'Halloran, Philip Thomas Scully, Paul Marshall, Eduardo Boada
  • Publication number: 20220168734
    Abstract: A microfluidic cassette has a microfluidic cassette body having at least one fluid flow channel and at least one chamber containing reagent. The chamber has a seal to prevent fluid from entering the chamber. The seal is breakable in situ in the cassette body. The cassette body and the chamber are configured such that when the seal is broken, the reagent is exposed to fluid flow in the channel.
    Type: Application
    Filed: November 28, 2019
    Publication date: June 2, 2022
    Inventors: Thomas Michael WILLSHARE, Hojjat MADADI, James BENNETT, Philip SCULLY
  • Publication number: 20220118451
    Abstract: Improved methods and devices using reduction of pressure for removing ethanol from filters in a fluidic or microfluidic system in point of care devices involve filters that are solid state extraction filters used to capture and/or concentrate nucleic acids prior to further downstream processing such as amplification by polymerase chain reaction. The method uses the induction of negative pressure with respect to atmospheric pressure to improve the efficiency of the ethanol removal process.
    Type: Application
    Filed: November 28, 2019
    Publication date: April 21, 2022
    Inventors: Hojjat MADADI, Robin PAGE, Molly Rose JOWSEY, Thomas Michael WILLSHARE, Roberts RIMSA
  • Publication number: 20220088590
    Abstract: Microfluidic devices with microfluidic cassettes allow for on-cassette processing of nucleic acids including amplification by polymerase chain reaction. In systems and methods of using the microfluidic device, the microfluidic cassette is pressurised prior to amplification of nucleic acid in said sample in an amplification/PCR section of the device.
    Type: Application
    Filed: November 28, 2019
    Publication date: March 24, 2022
    Inventors: Hojjat MADADI, Thomas Michael WILLSHARE, Robin PAGE
  • Publication number: 20200298232
    Abstract: A microfluidics device has one or more bubble diversion regions. Problems associated with the generation of air bubbles are avoided in a microfluidics device such as a cartridge, for use with a point of care (POC) diagnostics device, the cartridge being able to carry out downstream processing such as polymerase chain reaction (PCR) and/or nucleic acid capture. The bubble diversion region has a lower flow resistance than the flow resistance of an area of interest.
    Type: Application
    Filed: October 15, 2018
    Publication date: September 24, 2020
    Inventors: Hojjat MADADI, Thomas Michael WILLSHARE, Jonathan O'HALLORAN, Philip Thomas SCULLY, Paul MARSHALL, Eduardo BOADA
  • Patent number: D807729
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: January 16, 2018
    Assignee: NATIONAL OILWELL VARCO, L.P.
    Inventors: Thomas Michael Willshare, Richard Matthew Westgarth