Patents by Inventor Thomas Mietzner
Thomas Mietzner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180023060Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a mutated HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: ApplicationFiled: February 10, 2016Publication date: January 25, 2018Inventors: Stefan Tresch, Maciej Pasternak, Liliana Parra Rapado, Jill Paulik, Jens Lerchl, Gilbert Besong, Markus Kordes, Thomas Mietzner, Eva Stauffer
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Publication number: 20170226529Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: April 28, 2014Publication date: August 10, 2017Applicant: BASF SEInventors: Maciej PASTERNAK, Stefan TRESCH, Helmut KRAUS, Johannes HUTZLER, Jens LERCHL, Thomas MIETZNER, Jill Marie PAULIK
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Publication number: 20170114358Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: April 28, 2014Publication date: April 27, 2017Applicant: BASF SEInventors: Maciej PASTERNAK, Stefan TRESCH, Helmut KRAUS, Johannes HUTZLER, Jens LERCHL, Thomas MIETZNER, Jill Marie PAULIK
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Publication number: 20170067075Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: April 29, 2014Publication date: March 9, 2017Applicant: BASF SEInventors: Maciej PASTERNAK, Stefan TRESCH, Johannes HUTZLER, Jens LERCHL, Thomas MIETZNER, Brigitte WESTON, Matthias WITSCHEL, Jill Marie Paulik
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Publication number: 20170029840Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of: providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a N-heterocyclyl-arylcarboxamide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a N-heterocyclyl-arylcarboxamide, and applying to said site an effective amount of said herbicide.Type: ApplicationFiled: April 28, 2014Publication date: February 2, 2017Applicant: BASF SEInventors: Maciej Pasternak, Stefan Tresch, Helmut Kraus, Johannes Hutzler, Jens Lerchl, Thomas Mietzner, Liliana Parra Rapado, Jill Marie Paulik
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Publication number: 20160374339Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.Type: ApplicationFiled: December 17, 2014Publication date: December 29, 2016Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchi, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
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Patent number: 9480259Abstract: The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.Type: GrantFiled: May 29, 2013Date of Patent: November 1, 2016Assignee: BASF SEInventors: Matthias Witschel, Frank Stelzer, Johannes Hutzler, Tao Qu, Thomas Mietzner, Klaus Kreuz, Klaus Grossmann, Raphael Aponte, Hans Wolfgang Hoeffken, Frederick Calo, Thomas Ehrhardt, Anja Simon, Liliana Parra Rapado
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Publication number: 20160200692Abstract: The invention relates to N-(1,2,4-triazol-3-yl)arylcarboxamides of formula I and their use as herbicides. In said formula I, X represents N or CR2, whereas R1, R2, R3, R4, R5, R6 and R7 represent groups such as hydrogen, halogen or organic groups such as alkyl or phenyl.Type: ApplicationFiled: July 8, 2014Publication date: July 14, 2016Inventors: Frederick CALO, Markus KORDES, Helmut KRAUS, Thomas MIETZNER, Thomas SEITZ, Klaus KREUZ, Maciej PASTERNAK, Trevor William NEWTON, Dario MASSA
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Publication number: 20160201078Abstract: The invention refers to plants comprising wild-type or mutated Alopecurus PPO enzymes, and methods of obtaining such plants. The present invention further refers to a method for controlling weeds at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated Alopecurus PPO enzyme which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide.Type: ApplicationFiled: August 12, 2014Publication date: July 14, 2016Applicant: BASF AGRO B.V.Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
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Publication number: 20160194655Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.Type: ApplicationFiled: August 12, 2014Publication date: July 7, 2016Applicant: BASF AGRO B.V.Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
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Publication number: 20160194654Abstract: The present invention refers to a plant or plant part comprising (i) a recombinant polynucleotide encoding a wildtype or mut-PPO polypeptide, and (ii) a recombinant polynucleotide encoding a CYP450 polypeptide, the expression of said polynucleotides (i) and (ii) confers to the plant or plant part tolerance to PPO-inhibiting herbicides.Type: ApplicationFiled: August 12, 2014Publication date: July 7, 2016Applicant: BASF AGRO B.V.Inventors: Raphael Aponte, Stefan Tresch, Mathias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Doreen Schachtschabel, Jill Marie Paulik, Chad Brommer
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Publication number: 20160108008Abstract: N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of formula I and their use as herbicides, The invention relates to N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of formula I and their use as herbicides. In said formula I, B represents N or CH, R2 represents alkoxy, haloalkoxy, alkoxyalkoxy and R2b—S(O)k, whereas R, R1, R3, R4 and R5 represent groups such as hydrogen, halogen or organic groups such as alkyl or phenyl.Type: ApplicationFiled: May 5, 2014Publication date: April 21, 2016Applicant: BASF SEInventors: Helmut KRAUS, Frederick CALO, Matthias WITSCHEL, Thomas SEITZ, Trevor William NEWTON, Dario MASSA, Thomas MIETZNER, Maciej PASTERNAK, Klaus KREUZ, Richard Roger EVANS, Jens LERCHL
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Publication number: 20160102317Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, preferably a bicycloarylcarboxamide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: April 28, 2014Publication date: April 14, 2016Applicant: BASF SEInventors: Maciej Pasternak, Stefan Tresch, Helmut Kraus, Johannes Hutzler, Jens Lerchl, Thomas Mietzner, Liliana Parra Rapado, Jill Marie Paulik
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Publication number: 20150322453Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding an Alopecurus cytochrome P450 monooxygenase, as well as to the nucleic acid, and plants with increased herbicide tolerance or resistance comprising the nucleic acid of the invention. Furthermore, the present invention refers to methods of controlling weeds at a locus which contains a plant with increased herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: ApplicationFiled: December 13, 2013Publication date: November 12, 2015Applicant: BASF SEInventors: Stefan Tresch, Doreen Schachtschabel, Maciej Pasternak, Liliana Parra Rapado, Jens Lerchl, Thomas Mietzner, Martin Laforest
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Publication number: 20150252379Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.Type: ApplicationFiled: December 15, 2011Publication date: September 10, 2015Applicant: BASF SEInventors: Johannes Hutzler, Raphael Aponte, Thomas Mietzner, Matthias Witschel, Anja Simon, Jens Lerchl, Stefan Tresch, S. Luke Mankin
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Publication number: 20150126371Abstract: The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.Type: ApplicationFiled: May 29, 2013Publication date: May 7, 2015Inventors: Matthias Witschel, Frank Stelzer, Johannes Hutzler, Tao Qu, Thomas Mietzner, Klaus Kreuz, Klaus Grossmann, Raphael Aponte, Hans Wolfgang Hoeffken, Frederick Calo, Thomas Ehrhardt, Anja Simon, Liliana Parra Rapado
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Publication number: 20150005168Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a coumarone-derivative herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a coumarone-derivative herbicide, and applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: October 31, 2012Publication date: January 1, 2015Applicant: BASF SEInventors: Johannes Hutzler, Stefan Tresch, Thomas Mietzner, Matthias Witschel, Jens Lerchl, Raphael Aponte, Liliana Parra Rapado, Jill Marie Paulik
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Patent number: 8921273Abstract: Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.Type: GrantFiled: March 23, 2011Date of Patent: December 30, 2014Assignee: BASF SEInventors: Dschun Song, Julia Major, Johannes Hutzler, Trevor William Newton, Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Tao Qu, Frank Stelzer, Andree Van Der Kloet, Thomas Seitz, Thomas Ehrhardt, Klaus Kreuz, Klaus Grossmann, Anna Aleksandra Michrowska-Pianowska, Anja Simon, Ruediger Reingruber, Helmut Kraus, Hans Wolfgang Hoeffken, Thomas Mietzner
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Publication number: 20140357487Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a coumarone-derivative herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a coumarone-derivative herbicide, and applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.Type: ApplicationFiled: October 30, 2012Publication date: December 4, 2014Applicant: BASF SEInventors: Johannes Hutzler, Stefan Tresch, Thomas Mietzner, Matthias Witschel, Jens Lerchl, Raphael Aponte, Liliana Parra Rapado, Jill Marie Paulik
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Patent number: 8809535Abstract: Substituted pyridines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.Type: GrantFiled: March 21, 2011Date of Patent: August 19, 2014Assignee: BASF SEInventors: Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Tao Qu, Frank Stelzer, Andree Van Der Kloet, Thomas Seitz, Thomas Ehrhardt, Klaus Kreuz, Klaus Grossmann, Anna Aleksandra Michrowska-Pianowska, Anja Simon, Ruediger Reingruber, Helmut Kraus, Dschun Song, Julia Major, Johannes Hutzler, Trevor William Newton, Hans Wolfgang Hoeffken, Thomas Mietzner