Abstract: A three-dimensional structure is formed when layers of a material are deposited onto a substrate and scanned with a high energy beam to at least partially melt each layer of the material. Upon scanning the layers at predetermined locations at least a first segment overlapping a second segment and underlapping a third segment is formed.

Abstract: Systems and methods for managing cybersecurity for an entity are disclosed. An example method includes providing a content portal to a user configured to display a security risk profile via a generated GUI; receiving, via the generated GUI, a first input from the user comprising a selection of a component identified in the security risk profile and a response parameter; providing, via the generated GUI, parameters for a targeted scan of the selected component; receiving, via the generated GUI, a second input from the user comprising a selection of a confirmation of the parameters; identifying a vulnerability associated with a first property or a second property from device connectivity data based on the parameters; initiating the targeted scan of the selected component associated with the vulnerability; determining a result of the targeted scan; updating the security risk profile; and updating a multi-dimensional score based on the updated security risk profile.

Abstract: Documents and other process area events in an Enterprise Resource Planning (ERP) system are extracted according to a knowledge table. The extracted events are stitched together in a timeline order, placed in a transport container (or otherwise transmitted), and input to, for example, a process mining or process intelligence tool. The tool utilizes any of AI, Machine learning, or other techniques to evaluate processes and/or documents represented by the extracted events, and triggering alerts or messages based on the evaluation. The tool may be a task mining tool and/or provide information or suggestions for improving the document or process represented by the document(s) and may prepare and display (or provide for display) a visual model of the evaluated process or document and may highlight anomalies therein.

Abstract: Disclosed in certain embodiments is a method of treating respiratory depression modulated by a non-opioid agent comprising administering, to a patient in need thereof, an effective amount of a compound selected from Formula (I) as disclosed herein.

Abstract: Aspects of the subject disclosure may include, for example, receiving a request to forecast allocations for a new descriptor, the new descriptor differing from preexisting descriptors, each of the preexisting descriptors being associated with a subset of locations of a network of locations, each location corresponding to an electronic segment in electronic canvases, and the new descriptor being associated with a new subset of locations of the network of locations, identifying one or more affected descriptors having one or more overlapping subsets of locations of the network of locations and one or more non-overlapping subsets of locations of the network of locations, determining a forecast of allocated locations in each of the one or more affected descriptors; identifying, according to the forecast, at least a portion of allocated locations in the one or more overlapping subsets of locations that are displaceable resulting in a number of displaceable allocations, and determining, according to the number of di

Abstract: Systems, methods, and computer-readable storage media are utilized to analyze multi-channel data based on a security model in a computer network environment. One system includes a plurality of data channels configured to access entity data and a processing circuit communicatively coupled to a data channel of the plurality of data channels, the processing circuit configured to identify at least one vulnerability, determine an impact of the at least one vulnerability, assign the first property to a first cybersecurity dimension, generate a cybersecurity risk score based at least on the impact of the at least one vulnerability, and generate a multi-dimensional score for a target computer network environment based on the cybersecurity risk score.

Abstract: A lunar articulating mirror array system and method of use, in particular a lunar articulating mirror array for powering solar thermal processes in a lunar environment. The system redirects solar radiation using a masted heliostat array. The face of the array is composed of independently actuated concentrating mirrors which form a variable focal position Fresnel reflector. In one aspect, the lunar articulating mirror array system may redirect solar flux with controllable and selectable solar concentration ratios and may replicate any reflective optic geometry.

Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises activating a transceiver of a first communication device associated with an analyte sensor at a first time. The method also includes establishing a two-way communication channel with the second communication device. The activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.

Abstract: The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Abstract: A variable masking scheme for attenuating undesired optical artifact (26, 28, 30, 32) appearing in overlap regions (20, 22) between adjacent projection tiles (12, 14, 16) of a multi-projector (1, 2, 3) projection system (10). Different portions (54, 60) of a projection beam (43) are blocked by a mask apparatus (34) in response to a value (66) of a variable associated with a projected scene in order to attenuate respective artifacts correlated with that variable. The variable may be an optical parameter such as brightness (e.g., for a nighttime scene versus a dawn scene) or color, and the artifacts may be bright spots or shadows. The variable masking scheme may involve moving a single mask (36) to multiple positions or using multiple alternative masks (50, 56) in response to the variable.

Abstract: The subject technology provides for visualizing a route traversed by a user during a movement event by periodically obtaining position information data from a receiver of a navigation system during a movement event. A path traversed by a user of a device that includes the receiver during the movement event is estimated based on the position information data. One or more previously mapped features within a proximity of the estimated path on a map are determined. The estimated path is matched to the map based on the previously mapped features to obtain a map-matched path. A display device is caused to render the map-matched path on an image of the map.

Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Sound-producing acoustic receivers are disclosed. The acoustic receiver includes a receiver housing with a first internal volume and a second internal volume, a first diaphragm separating the first internal volume into a first front volume and a first back volume such that the first front volume has a first sound outlet port, a second diaphragm separating the second internal volume into a second front volume and a second back volume such that the second front volume has a second sound outlet port, a motor disposed at least partially inside the housing such that the motor including an armature mechanically coupled to both the first diaphragm and the second diaphragm, an acoustic seal between the first front volume and the second back volume such that the acoustic seal accommodates the mechanical coupling of the armature to one of the first diaphragm or the second diaphragm.

Abstract: Disclosed in certain embodiments is a method of treating respiratory depression modulated by a non-opioid agent comprising administering, to a patient in need thereof, an effective amount of a compound selected from Formula (I) as disclosed herein.

Abstract: An ear-worn hearing device with occlusion reduction is disclosed. The hearing device includes a signal processor configured to generate an anti-occlusion signal based on a feedforward signal from a vibration sensor located to detect tissue-propagated vibration within the user's at least partially occluded ear canal. Optionally, the anti-occlusion signal can also be based on a feedback signal from a microphone located to detect sound within the at least partially occluded ear canal. Unwanted vibrations detected by the vibration sensor can optionally be removed from the anti-occlusion signal based on filtering the anti-occlusion signal.

Abstract: An analyzer for analysis of a biological sample prepared by a pre analytical system and a method of operating an analyzer that received samples prepared by a pre-analytical system. The analyzer is automated and has a processing deck with a plurality of modules serviced by a plurality of multichannel pipettors. Due to the high volume of pipette tips used by and dispensed from the multichannel pipettors, the processing deck has a pipette dispense assembly having a plurality of chutes, so that a multichannel pipettor does not need to wait to discard a pipette tip into a chute. The plurality of chutes allows the pipette tips to fall therethrough to a waste receptacle below the processing deck. The processing deck also includes a plurality of drawers that contain bins for consumable pipette tips to be used by the multichannel pipettors. Some of the drawers have multiple bins and some have only one bin because the location of the chutes does not permit all drawers to have the same depth.

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: Compounds of formula I and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: An electrochemically active structure having a core and a shell at least partially surrounding the core. Also a method of making the electrochemically active structure as described herein as well as electrochemical cells comprising the electrochemically active structure as described herein.

Abstract: The disclosure provides processes for synthesizing Compound I, and pharmaceutically acceptable salts thereof.