Patents by Inventor Thomas Milner

Thomas Milner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240057935
    Abstract: Internal cervical exams during labor pose multiple challenges, including infection risk, subjectivity, invasiveness, and discomfort. A monitoring system described herein enables non-invasive and accurate measurement of cervical dilation and assessment of the baby's station. By inserting a narrow linear ultrasound probe through the working channel, high-resolution ultrasound images of the cervix can be obtained, eliminating the need for painful and subjective exams, reducing infection risk, and enhancing patient comfort. Moreover, the ultrasound capability allows for potential monitoring of maternal and fetal blood oxygenation levels, providing a comprehensive picture of fetal well-being.
    Type: Application
    Filed: August 21, 2023
    Publication date: February 22, 2024
    Inventors: Lourdes Swentek, Thomas Milner, Nitesh Katta, Yona Tadir
  • Publication number: 20230386815
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: July 28, 2023
    Publication date: November 30, 2023
    Inventors: Livia Schiavinato EBERLIN, Thomas MILNER, Jialing ZHANG, John LIN, John RECTOR, Nitesh KATTA, Aydin ZAHEDIVASH
  • Patent number: 11756778
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: September 12, 2023
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, John Lin, John Rector, Nitesh Katta, Aydin Zahedivash
  • Patent number: 11737671
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for minimally invasive collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: August 29, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, Noah Giese, Nitesh Katta
  • Publication number: 20220310378
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: December 30, 2021
    Publication date: September 29, 2022
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato EBERLIN, Thomas MILNER, Jialing ZHANG, John LIN, John RECTOR, Nitesh KATTA, Aydin ZAHEDIVASH
  • Publication number: 20220296102
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for minimally invasive collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: November 5, 2021
    Publication date: September 22, 2022
    Applicant: Board of Regents, The University of Texas System
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, Noah Giese, Nitesh Katta
  • Publication number: 20220268784
    Abstract: In a general aspect, methods and devices are provided for using mass spectrometry to identify endometriosis. In some aspects, a fixed or discrete volume of a solvent is applied to a tissue site including possible endometriosis tissue. The applied solvent is collected to obtain a liquid sample. The liquid sample is subjected to mass spectrometry analysis. The liquid sample is collected from a tissue site in vivo during a medical procedure. The mass spectrometry data are analyzed to identify whether the tissue site comprises endometriosis.
    Type: Application
    Filed: December 6, 2021
    Publication date: August 25, 2022
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato Eberlin, Michael T. Breen, Jialing Zhang, Clara L. Feider, John Lin, Thomas Milner
  • Publication number: 20220192537
    Abstract: The present invention features an optical detection system for SARS-CoV-2 or other pathogens, which includes a specialty mask. The specialty mask incorporates a SERS nanopatch for accumulating pathogenic particles from a wearers breath. When the SERS nanopatch receives incident NIR light, backscattered light from the SERS nanopatch is detected by a receiver and analyzed for a Raman spectral shift. Detection of the Raman spectral signature from the SERS nanopatch allows for determination if SARS-CoV-2 or another pathogen is present. In addition to the mask with a nanostructured surface for collecting pathogenic material, the system includes a laser source directed at the nanostructured surface, a detection system to collect backscattered light, a spectral analysis system to detect Raman shifted light, and an analysis system for determining if SARS-CoV-2 or another pathogen is present. AI image processing may be used to steer the laser beam safely to the nanopatch, avoiding eye contact.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 23, 2022
    Inventors: Thomas Milner, Robert G. W. Brown, Nitesh Katta, Matthew Brenner, James Tunnell, Mohadeseh Hashemidehagi, Raj Nihalani, Wangcun Jia
  • Publication number: 20220196697
    Abstract: Methods and apparatus are provided for cleaning or exchanging medical devices. Certain embodiments may include a cassette comprising a plurality of medical devices, where the orientation of the cassette can be changed while the cassette is coupled to a processing instrument.
    Type: Application
    Filed: July 23, 2021
    Publication date: June 23, 2022
    Inventors: Livia SCHIAVINATO EBERLIN, Thomas MILNER, Jialing ZHANG, Noah GIESE, John LIN, Jeffrey R. KUHN, James SULIBURK, Nitesh KATTA
  • Patent number: 11239065
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: February 1, 2022
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, John Lin, John Rector, Nitesh Katta, Aydin Zahedivash
  • Publication number: 20210338092
    Abstract: A portable device for quantitative measurement of tissue autoregulation and neurovascular coupling via portable measurement of blood flow, oxygenation, metabolism, and/or EEG signals and methods for using said device. The device may comprise a body and a plurality of legs pivotably attached to the body. The plurality of legs may comprise at least one reference electrode leg and at least one measurement electrode leg for electrical measurement, and an optical detection fiber leg and at least one optical source fiber leg for optical blood flow, oxygenation, and metabolism measurement. The present invention is additionally directed to a portable device for blood flow measurement and therapeutic photobiomodulation. The device may comprise a body and a plurality of legs. The plurality of legs may comprise at least one optical detection fiber leg and at least one optical source fiber leg, and at least one leg for therapeutic photobiomodulation.
    Type: Application
    Filed: July 15, 2021
    Publication date: November 4, 2021
    Inventors: Yama Akbari, Robert H. Wilson, Christian Crouzet, Thomas Milner, Bernard Choi
  • Publication number: 20210257202
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: November 30, 2020
    Publication date: August 19, 2021
    Inventors: Livia Schiavinato EBERLIN, Thomas MILNER, Jialing ZHANG, John LIN, John RECTOR, Nitesh KATTA, Aydin ZAHEDIVASH
  • Patent number: 10943775
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: March 9, 2021
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, John Lin, John Rector, Nitesh Katta, Aydin Zahedivash
  • Publication number: 20200367761
    Abstract: The present invention is directed to a portable device for quantitative measurement of tissue autoregulation and neurovascular coupling via portable measurement of blood flow, oxygenation, metabolism, and/or EEG signals and methods for using said device. The device may comprise a body and a plurality of legs pivotably attached to the body. The plurality of legs may comprise at least one reference electrode leg and at least one measurement electrode leg for electrical measurement, and an optical detection fiber leg and at least one optical source fiber leg for optical blood flow, oxygenation, and metabolism measurement. The present invention is additionally directed to a portable device for blood flow measurement and therapeutic photobiomodulation. The device may comprise a body and a plurality of legs. The plurality of legs may comprise at least one optical detection fiber leg and at least one optical source fiber leg, and at least one leg for therapeutic photobiomodulation.
    Type: Application
    Filed: August 4, 2020
    Publication date: November 26, 2020
    Inventors: Yama Akbari, Robert H. Wilson, Christian Crouzet, Thomas Milner, Bernard Choi
  • Publication number: 20200305723
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for minimally invasive collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: May 26, 2020
    Publication date: October 1, 2020
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, Noah Giese, Nitesh Katta
  • Publication number: 20200279728
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: March 13, 2020
    Publication date: September 3, 2020
    Inventors: Livia Schiavinato EBERLIN, Thomas MILNER, Jialing ZHANG, John LIN, John RECTOR, Nitesh KATTA, Aydin ZAHEDIVASH
  • Patent number: 10643832
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: May 5, 2020
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Livia Schiavinato Eberlin, Thomas Milner, Jialing Zhang, John Lin, John Rector, Nitesh Katta, Aydin Zahedivash
  • Patent number: 10495440
    Abstract: Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: December 3, 2019
    Assignee: Research Development Foundation
    Inventors: Marc Feldman, Thomas Milner, Tianyi Wang, Jennifer Whedbee
  • Publication number: 20180158661
    Abstract: Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
    Type: Application
    Filed: August 31, 2017
    Publication date: June 7, 2018
    Inventors: Livia Schiavinato EBERLIN, Thomas MILNER, Jialing ZHANG, John LIN, John RECTOR, Nitesh KATTA, Aydin ZAHEDIVASH
  • Publication number: 20180143147
    Abstract: An apparatus and method for detecting defects in an additive manufacturing process is provided. An example method may include depositing a first layer of material, depositing a second layer of material in at least partial contact with the first layer of material, and inducing a phase change between the first and second layers of material via an energy beam. Further, the method may include directing an electromagnetic radiation beam to at least a portion of a subsurface interface between the first and second layers, measuring radiation returned from the material, and based on the measured radiation, determining a location of a refractive index gradient within the material.
    Type: Application
    Filed: May 11, 2016
    Publication date: May 24, 2018
    Inventors: Thomas Milner, Austin McElroy, Joseph Beaman, Scott Fish