Patents by Inventor Thomas Min STEPHAN

Thomas Min STEPHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified S1 subunit of the coronavirus spike protein
    Patent number: 11964999
    Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: April 23, 2024
    Assignee: Boehringer Ingelheim Vetmedia GmbH
    Inventors: Annika Kraemer-Kuehl, Thomas Min Stephan, Hans-Christian Philipp
  • MODIFIED S1 SUBUNIT OF THE CORONAVIRUS SPIKE PROTEIN
    Publication number: 20230340028
    Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
    Type: Application
    Filed: November 28, 2022
    Publication date: October 26, 2023
    Applicant: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Annika KRAEMER-KUEHL, Thomas Min STEPHAN, Hans-Christian PHILIPP
  • Modified S1 subunit of the coronavirus spike protein
    Patent number: 11512115
    Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
    Type: Grant
    Filed: May 6, 2020
    Date of Patent: November 29, 2022
    Inventors: Annika Kraemer-Kuehl, Thomas Min Stephan, Hans-Christian Philipp
  • MODIFIED S2 SUBUNIT OF THE CORONAVIRUS SPIKE PROTEIN
    Publication number: 20220213148
    Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 865. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
    Type: Application
    Filed: May 6, 2020
    Publication date: July 7, 2022
    Inventors: Annika KRAEMER-KUEHL, Thomas Min Stephan
  • ATTENUATED IBV WITH EXTENDED CELL CULTURE AND TISSUE TROPISM
    Publication number: 20220202931
    Abstract: The present invention relates i.a. to an IBV (infectious bronchitis virus) deposited with the BVR of IZSLER under accession number DPS RE RSCIC 16, any descendant IBV thereof and any IBV having all of the identifying characteristics of the deposited IBV. Further, the present invention relates to an immunogenic composition comprising said deposited IBV.
    Type: Application
    Filed: May 6, 2020
    Publication date: June 30, 2022
    Inventors: Egbert Siegfried MUNDT, Annika KRAEMER-KUEHL, Rosalba DE LA MORA QUIROZ, Jose Francisco ROBLES GONZALEZ, Thomas Min Stephan
  • MODIFIED S1 SUBUNIT OF THE CORONAVIRUS SPIKE PROTEIN
    Publication number: 20200354410
    Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
    Type: Application
    Filed: May 6, 2020
    Publication date: November 12, 2020
    Inventors: Annika KRAEMER-KUEHL, Thomas Min STEPHAN, Hans-Christian PHILIPP