Abstract: Rapid transfer port (RTP) systems for transferring articles between two environments (e.g., an isolator barrier system and a transfer container) are provided. Such systems may be adapted to be mated to one another by a docking operation. More particularly, such systems may provide a container assembly for use with an RTP of the type that does not require the transfer container port (beta port) which mates, for example, with the isolator barrier system port (alpha port) to breach the integrity of the container until attachment to the isolator barrier system port (alpha port 9). The container assembly may have an enclosure that, during docking, is not required to be exposed to the clean environment such as an isolator barrier system.