Abstract: A syringe with a closure is disclosed. The syringe comprises a needle projecting from a syringe body, the tip of the needle being enclosed by a closure cap when the syringe is in a closed position. A sealing element is provided for sealing the needle in the closed position. The sealing element has an annular, elastically deformable portion that can be sealingly pressed against the outer surface of the needle by means of the closure cap.

Abstract: A method for producing a multi-chamber syringe with a by-pass channel from a plastic material comprises the steps of producing a tubular preform from a thermoplastic material; providing a die designed to enclose the preform from the outside in an area of the by-pass channel to be formed, the at least one by-pass channel being preformed as a recess on an inner surface of the die; heating-up the preform to a temperature above the softening range of the plastic material, and positioning the preform in a predefined axial position inside the die; subjecting the preform to a differential pressure until the at least one by-pass channel is plastically formed; and cooling down the syringe body so formed to room temperature.

Abstract: A syringe with a closure is disclosed. The syringe comprises a needle projecting from a syringe body, the tip of the needle being enclosed by a closure cap when the syringe is in a closed position. A sealing element is provided for sealing the needle in the closed position. The sealing element has an annular, elastically deformable portion that can be sealingly pressed against the outer surface of the needle by means of the closure cap.