Patents by Inventor Thomas Mole

Thomas Mole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190004052
    Abstract: The present invention concerns the use of immunoassays for the characterisation, diagnosis, screening and monitoring of cancer and other diseases. In particular said immunoassays involve the use of polyclonal and monoclonal antibodies against different regions in tissue factor, particularly urinary tissue factor, and methods for generating the same. Preferably said antibodies are specific for the tissue factor signal transduction peptide region (anti-TF-STP antibodies). In particular, the present invention relates to antibodies and the use thereof which are specific for phosphorylated isoforms of TF-STP. The invention further concerns use of these anti-TF-STP antibodies to quantitate TF-STP isoforms in biological fluids, in particular urine.
    Type: Application
    Filed: June 20, 2016
    Publication date: January 3, 2019
    Inventors: Thomas Mole HERD, Robert Scott GREENFIELD
  • Publication number: 20130203077
    Abstract: We provide a novel technological approach for quantitation of c-terminal fragment of uTF for the purpose of quantitation, diagnosis and population screening of cancer. We provide a rationale for measuring c-terminal fragment, methods for making assays, monoclonal and polyclonal antibodies, together with accepted methods of sample preparation. Taken together these proposals and ideas constitute a novel approach for diagnosis and population screening for cancers using urine from cancer patients. In addition we believe that our approach may be useful in the diagnosis of other pathological conditions.
    Type: Application
    Filed: October 19, 2011
    Publication date: August 8, 2013
    Applicant: C-TERM DIAGNOSTICS LIMITED
    Inventors: Thomas Mole Herd, Robert Greenfield
  • Patent number: 5019661
    Abstract: Branched olefins of at least 4 carbon atoms are hydroisomerized to a less branched alkane by contact with a hydrogen containing gas and a shape selective zeolite which has at least 1 metal of the Pt group supported primarily within the channels of said zeolite.
    Type: Grant
    Filed: June 1, 1989
    Date of Patent: May 28, 1991
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Broken Hill Proprietary Company Limited
    Inventor: Thomas Mole
  • Patent number: 4554393
    Abstract: A process for the production of aromatic compounds from low-molecular weight predominantly paraffinic feedstock which comprises contacting the feedstock in a first reactor with a dehydrogenation catalyst to produce a first reaction product containing alkenes; contacting said first reaction product in a second reactor with a crystalline aluminosilicate catalyst to produce a second reaction product containing aromatics; and separating an aromatic-rich fraction therefrom. In a preferred embodiment the feedstock consists essentially of propane and/or butane.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: November 19, 1985
    Assignees: The Broken Hill Proprietary Company Limited, Commonwealth Scientific and Industrial Research Organisation
    Inventors: Sandra Liberts, Jack G. Creer, Thomas Mole
  • Patent number: 4499314
    Abstract: A process for producing hydrocarbons comprising contacting, under conversion conditions, an aqueous methanol with a crystalline aluminosilicate zeolite catalyst which is hydrothermally stable in the temperature range of from 250.degree. C. to 500.degree. C. and is capable of converting methanol to hydrocarbons, and with a promoter comprising one or more compounds selected from the group consisting of aromatic hydrocarbons, precursors to aromatic hydrocarbons, olefins, precursors to olefins and aldehydes to form a mixture comprising light olefins, lower alkanes and monocyclic aromatic hydrocarbons and recovering said hydrocarbons.
    Type: Grant
    Filed: April 30, 1984
    Date of Patent: February 12, 1985
    Assignee: Imperial Chemical Industries PLC
    Inventors: Duncan Seddon, Thomas Mole, Judy A. Whiteside
  • Patent number: 4338477
    Abstract: The invention concerns a process for the removal of catalyst residues from a gas by contacting the gas with particulate mineral oxides. The process of the invention may be applied to the removal of coordination catalyst residues from .alpha.-olefins recycled from a polymerization reactor. The process is particularly useful in the removal of alkylaluminium halides and hydrogen halides, such as diethylaluminium chloride and hydrogen chloride, from .alpha.-olefins such as propylene. The process offers the advantages of being able to be operated under anhydrous conditions, and combining high efficiency in the removal of low levels of catalyst residues with a high capacity for the catalyst residues.
    Type: Grant
    Filed: July 22, 1980
    Date of Patent: July 6, 1982
    Assignees: ICI Australia Limited, Commonwealth Scientific and Industrial Research Organization
    Inventors: Keith Moody, Thomas Mole